Results 341 to 350 of about 465,571 (364)

Construction of nanoantennas on the bacterial outer membrane

Chem. Commun., 2014
A simple and highly sensitive detection of pathogenic bacteria is achieved by utilizing gold nanoparticles as an optical antenna.
Kaori Takada, Yojiro Yamamoto, Takatoshi Tono, Tsutomu Nagaoka, Tomoaki Nishino, Tomoyuki Okada, Takamasa Kinoshita, Hiroshi Shiigi, Le Quynh Dung, Maho Fukuda, Yu Hatsuoka, Hidenobu Nakao, Masahiro Takai, Shiho Tokonami   +13 more
openaire   +3 more sources

Clinically Relevant Bacterial Outer Membrane Models for Antibiotic Screening Applications.

ACS Infectious Diseases, 2021
Antibiotic resistance is a growing global health concern that has been increasing in prevalence over the past few decades. In Gram-negative bacteria, the outer membrane is an additional barrier through which antibiotics must traverse to kill the ...
Zeinab Mohamed, Jung-Ho Shin, Surajit Ghosh, A. Sharma, Ferra Pinnock, Samavi Bint E Naser Farnush, Tobias Dörr, S. Daniel   +7 more
semanticscholar   +1 more source

Assembly of Bacterial Outer Membrane Proteins

2012
Various methods that are routinely used to study the subcellular localization of membrane proteins in wild-type Gram-negative bacteria fall short in genetic studies addressing the biogenesis of outer membrane proteins (OMPs). Here, we describe three biochemical methods that can be used in such studies to evaluate the proper assembly of OMPs into the ...
Martine P. Bos, Jan Tommassen, Jan Grijpstra   +2 more
openaire   +4 more sources

Modified Bacterial Outer Membrane Vesicles Induce Autoantibodies for Tumor Therapy

Acta Biomaterialia, 2020
Using monoclonal antibodies to block tumor angiogenesis has yielded effective antitumor effects. However, this treatment method has long cycles and is very expensive; therefore, its long-term and extensive application is limited.
Weiwei Huang, Congyan Shu, Liangqun Hua, Yilin Zhao, Hanghang Xie, Jia-long Qi, Fulan Gao, Ruiyu Gao, Yongjun Chen, Qishu Zhang, Weiran Li, Mingcui Yuan, Chao Ye, Yanbing Ma   +13 more
semanticscholar   +1 more source

Secretion across the bacterial outer membrane

Trends in Genetics, 1992
Many bacteria secrete extracellular proteins such as hydrolytic enzymes or toxins. In Gram-negative bacteria, secreted proteins must cross the two membranes that constitute the cell envelope. Recent studies have identified several specific secretion systems that can be classified in three distinct pathways, and related systems have been discovered in a
openaire   +3 more sources

The bacterial outer membrane as a drug barrier

Trends in Microbiology, 1997
The outer membranes of Gram-negative bacteria constitute a semi-permeable barrier, as indicated by the corresponding alterations in outer membrane permeability and in antibiotic susceptibility resulting from mutation or polycation action. Restricted outer membrane permeability works in synergy with co-determinant resistance mechanisms, such as the ...
openaire   +3 more sources

Salmonella cytotoxin: a component of the bacterial outer membrane

Microbial Pathogenesis, 1986
Salmonella cytotoxin present in cell-free sonic lysates causes rounding and detachment of Chinese hamster ovary (CHO) cells. Although the precise role of this toxin in the pathogenesis of salmonellosis is unclear, cytotoxin production by Salmonella could account for tissue damage or possibly, facilitate invasion.
Johnny W. Peterson, James C. Reitmeyer, Katharine J. Wilson   +2 more
openaire   +3 more sources

Transport across the bacterial outer membrane

Journal of Bioenergetics and Biomembranes, 1993
Diffusion of small molecules across the outer membrane of gram-negative bacteria may occur through protein channels and through lipid bilayer domains. Among protein channels, many examples of trimeric porins, which produce water-filled diffusion channels, are known.
openaire   +3 more sources

Bacterial outer membrane evolution via sporulation?

Nature Chemical Biology, 2011
The distinction between different cell-envelope architectures has defined much of our thinking about bacterial systematics, but the evolution of different envelope layers has been harder to understand. A recent publication focused on the non-model organism Acetonema longum provides important clues to the possible origin of the second membrane typical ...
openaire   +4 more sources

Advances in understanding bacterial outer-membrane biogenesis

Nature Reviews Microbiology, 2006
The outer membrane of gram-negative bacteria such as Escherichia coli serves as a protective barrier that controls the influx and efflux of solutes. This allows the bacteria to inhabit several different, and often hostile, environments. The assembly of the E.
Thomas J. Silhavy, Daniel Kahne, Natividad Ruiz   +2 more
openaire   +3 more sources