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Lipopolysaccharide and the Permeability of the Bacterial Outer Membrane
2020Lipopolysaccharide (LPS) is not only a potent toxin (endotoxin), but also the major constituent of the unique cell surface structure, the outer membrane (OM), of gram-negative bacteria. The characteristic features of the OM of gram-negative enteric bacteria include that the LPS molecules are located exclusively in the outer leaflet and the ...
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Porins and specific channels of bacterial outer membranes
Molecular Microbiology, 1992SummaryPorins and specific channels both produce water‐filled pores that allow the transmembrane diffusion of small solutes, but the latter contain specific ligandbinding sites within the channels. Recent structural studies show that many or most of these proteins exist as βbarrels with the βstrands traversing the thickness of the outer membrane.
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Porin from Bacterial and Mitochondrial Outer Membrane
Critical Reviews in Biochemistry, 1985The outer membrane of gram-negative bacteria acts as a molecular filter with defined exclusion limit for hydrophilic substances. The exclusion limit is dependent on the type of bacteria and has for enteric bacteria like Escherichia coli and Salmonella typhimurium a value between 600 and 800 Daltons, whereas molecules with molecular weights up to 6000 ...
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Modeling and simulation of bacterial outer membranes and interactions with membrane proteins
Current Opinion in Structural Biology, 2017The outer membrane (OM) of Gram-negative bacteria is composed of phospholipids in the periplasmic leaflet and lipopolysaccharides (LPS) in the external leaflet, along with β-barrel OM proteins (OMPs) and lipidated periplasmic lipoproteins. As a defensive barrier to toxic compounds, an LPS molecule has high antigenic diversity and unique combination of ...
Dhilon S Patel, Yifei Qi, Wonpil Im
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Biochemical Society Transactions, 1981 Lipoproteins from the Bacterial Outer Membranes
1982The envelope of gram-negative bacteria consists of two distinct membranes, the cytoplasmic membrane and the outer membrane. In contrast to the cytoplasmic membrane, the outer membrane contains a small number of major proteins, accounting for more than 90% of the total outer-membrane protein (see reviews by Inouye, 1979a; DiRienzo et al., 1978).
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Bacterial Outer Membranes Bacterial Outer Membranes: Biogenesis and Functions Masayori Inouye
BioScience, 1981G. D. Shockman, W. Wong
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Host immunity and cellular responses to bacterial outer membrane vesicles.
Trends in immunology, 2021Varnesh Tiku, M. Tan
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Bacterial Outer Membrane Protein Vaccines
1996With respect to bacterial vaccines, a number of approaches were found successful by way of empirical research, trial and error.
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Bacterial outer membrane vesicles and host cell death signaling.
Trends in Microbiology, 2021Subhash Dhital +3 more
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