Results 51 to 60 of about 328,822 (337)

Doxorubicin-loaded bacterial outer-membrane vesicles exert enhanced anti-tumor efficacy in non-small-cell lung cancer

Acta Pharmaceutica Sinica B, 2020
More efficient drug delivery system and formulation with less adverse effects are needed for the clinical application of broad-spectrum antineoplastic agent doxorubicin (DOX).
Kudelaidi Kuerban, Xiwen Gao, Hui Zhang, Jiayang Liu, Mengxue Dong, Lina Wu, Ruihong Ye, Meiqing Feng, Li Ye   +8 more
semanticscholar   +1 more source

The Proteome of Biologically Active Membrane Vesicles from Piscirickettsia salmonis LF-89 Type Strain Identifies Plasmid-Encoded Putative Toxins [PDF]

, 2017
Indexación: Scopus.Piscirickettsia salmonis is the predominant bacterial pathogen affecting the Chilean salmonid industry. This bacterium is the etiological agent of piscirickettsiosis, a significant fish disease.
Artigues, A., Avendaño-Herrera, R., Cortés, M.A., Haro, R.E., Hernández, M.A., Lagos, L.X., Oliver, C., Ruiz, P.A., Sanhueza-Oyarzún, C., Sánchez, P., Tandberg, J.I., Valenzuela, K.N., Villar, M.T., Winther-Larsen, H.C., Yáñez, A.J.   +14 more
core   +1 more source

Bacterial Outer Membrane Vesicles Presenting Programmed Death 1 for Improved Cancer Immunotherapy via Immune Activation and Checkpoint Inhibition.

ACS Nano, 2020
Natural, extracellular membrane vesicles secreted by Gram-negative bacteria, outer membrane vesicles (OMVs), contain numerous pathogen-associated molecular patterns which can activate systemic immune responses.
Yao Li, Ruifang Zhao, Keman Cheng, Kaiyue Zhang, Yazhou Wang, Yinlong Zhang, Yujing Li, Guangna Liu, Junchao Xu, Jiaqi Xu, G. Anderson, Jian Shi, L. Ren, Xiao Zhao, Guangjun Nie   +14 more
semanticscholar   +1 more source

Knockout of mlaA increases Escherichia coli virulence in a silkworm infection model.

PLoS ONE, 2022
The mlaA gene encodes a lipoprotein to maintain an outer membrane lipid asymmetry in gram-negative bacteria. Although the role of mlaA in bacterial virulence has been studied in several bacterial species, there are no reports of its role in E.
Haruka Nasu, Riko Shirakawa, Kazuyuki Furuta, Chikara Kaito   +3 more
doaj   +2 more sources

The role of bacterial secretion systems in the virulence of Gram-negative airway pathogens associated with cystic fibrosis [PDF]

, 2016
Cystic fibrosis (CF) is the most common lethal inherited disorder in Caucasians. It is caused by mutation of the CF transmembrane conductance regulator (CFTR) gene.
Depluverez, Sofie, Devos, Simon, Devreese, Bart   +2 more
core   +5 more sources

Oxidative protein biogenesis and redox regulation in the mitochondrial intermembrane space [PDF]

, 2016
Mitochondria are organelles that play a central role in cellular metabolism, as they are responsible for processes such as iron/sulfur cluster biogenesis, respiration and apoptosis.
MacPherson, Lisa, Manganas, Phanee, Tokatlidis, Kostas   +2 more
core   +1 more source

Bacterial outer membrane vesicle-cancer cell hybrid membrane-coated nanoparticles for sonodynamic therapy in the treatment of breast cancer bone metastasis

Journal of Nanobiotechnology
Breast cancer bone metastasis is a terminal-stage disease and is typically treated with radiotherapy and chemotherapy, which causes severe side effects and limited effectiveness.
Jiahao Wang, Shuailong Liang, Sijie Chen, Tianliang Ma, Mingyu Chen, Chengcheng Niu, Yi Leng, Long Wang   +7 more
semanticscholar   +1 more source

Surface Polysaccharide Extraction and Quantification

Bio-Protocol, 2013
Gram-negative bacterial cells possess two membranes - the inner cytoplasmic membrane and the outer membrane. The two membranes are distinct in their composition; the inner membrane is composed of a phospholipid bilayer, whereas the outer membrane (OM) is
Cedric Brimacombe, John Beatty
doaj   +1 more source

Molecular imaging of bacterial outer membrane vesicles based on bacterial surface display

Scientific Reports, 2023
The important roles of bacterial outer membrane vesicles (OMVs) in various diseases and their emergence as a promising platform for vaccine development and targeted drug delivery necessitates the development of imaging techniques suitable for quantifying
Dávid Szöllősi, Polett Hajdrik, Hedvig Tordai, Ildikó Horváth, Dániel S. Veres, Bernadett Gillich, Kanni Das Shailaja, László Smeller, Ralf Bergmann, Michael Bachmann, Judith Mihály, Anikó Gaál, Bálint Jezsó, Balázs Barátki, Dorottya Kövesdi, Szilvia Bősze, Ildikó Szabó, Tamás Felföldi, Erzsébet Oszwald, Parasuraman Padmanabhan, Balázs Zoltán Gulyás, Nazha Hamdani, Domokos Máthé, Zoltán Varga, Krisztián Szigeti   +24 more
doaj   +1 more source

Self-assembling dipeptide antibacterial nanostructures with membrane disrupting activity. [PDF]

, 2017
Peptide-based supramolecular assemblies are a promising class of nanomaterials with important biomedical applications, specifically in drug delivery and tissue regeneration.
Adler-Abramovich, Lihi, Brahmachari, Sayanti, Bychenko, Darya, DeGrado, William F, Gazit, Ehud, Kolusheva, Sofiya, Mensa, Bruk, Schmidt, Nathan W, Schnaider, Lee, Shaham-Niv, Shira, Shimon, Linda JW   +10 more
core   +3 more sources