Results 71 to 80 of about 158,347 (278)
Bioengineering bacterial outer membrane vesicles as vaccine platform [PDF]
Biotechnology Advances, 2017 Outer membrane vesicles (OMVs) are naturally non-replicating, highly immunogenic spherical nanoparticles derived from Gram-negative bacteria. OMVs from pathogenic bacteria have been successfully used as vaccines against bacterial meningitis and sepsis among others and the composition of the vesicles can easily be engineered.
Gerritzen, Thijs +4 more
openaire +4 more sources
Advanced Functional Materials, EarlyView.A battery‐free, wireless device for real‐time monitoring of pressure injury and hygiene integrates pressure (≈10 kPa), temperature (≈40 °C), and NH3 gas sensing with antibacterial functionality. Enabled by near‐field communication, it ensures simultaneous, interference‐free mechanical and chemical monitoring, offering a practical solution for pressure ...
Myungwoo Choi +19 more
wiley +1 more source
Biomaterial Strategies for Targeted Intracellular Delivery to Phagocytes
Advanced Functional Materials, EarlyView.Phagocytes are essential to a functional immune system, and their behavior defines disease outcomes. Engineered particles offer a strategic opportunity to target phagocytes, harnessing inflammatory modulation in disease. By tuning features like size, shape, and surface, these systems can modulate immune responses and improve targeted treatment for a ...
Kaitlyn E. Woodworth +2 more
wiley +1 more source
Advanced Functional Materials, EarlyView.Lanthanide ytterbium ions are introduced into Bi2WO6 nanosheets to boost ROS generation under US stimulation. These ytterbium‐doped Bi2WO6 nanosheets serve as efficient sonosensitizers, enabling broad‐spectrum bacterial eradication. To improve biocompatibility for in vivo sonodynamic therapy, the sonosensitizers are integrated into hydrogel matrix ...
Xinyue Lao +6 more
wiley +1 more source
Advanced Functional Materials, EarlyView.Bio‐based and (semi‐)synthetic zwitterion‐modified novel materials and fully synthetic next‐generation alternatives show the importance of material design for different biomedical applications. The zwitterionic character affects the physiochemical behavior of the material and deepens the understanding of chemical interaction mechanisms within the ...
Theresa M. Lutz +3 more
wiley +1 more source
Assembly and targeting of secretins in the bacterial outer membrane
International Journal of Medical Microbiology, 2019 In Gram-negative bacteria, secretion of toxins ensure the survival of the bacterium. Such toxins are secreted by sophisticated multiprotein systems. The most conserved part in some of these secretion systems are components, called secretins, which form the outer membrane ring in these systems. Recent structural studies shed some light on the oligomeric
Doron Rapaport +2 more
openaire +3 more sources
Advanced Functional Materials, EarlyView.A slippery coating with exceptional anti‐biofouling performance is developed using biocompatible materials for oesophagus stents. Host‐guest inclusion complex formation capabilities of FDA‐approved supramolecules, cyclodextrins are exploited, which significantly enhances the stability of the surface.
Jianhui Zhang +7 more
wiley +1 more source
Analyzing the molecular mechanism of lipoprotein localization in Brucella
Frontiers in Microbiology, 2015 Bacterial lipoproteins possess comprehensive structure and functionality, ranging from bacterial physiology to pathogenic processes. As such many lipoproteins, originating from Brucella are exploited as potential vaccines to countermeasure brucellosis ...
Shivani eGoolab +4 more
doaj +1 more source
Advanced Functional Materials, EarlyView.This review discusses cellulose‐based hydrogels technology, analyzes their application progress in physiological signal monitoring, and explores the effects of pretreatment, crosslinking, and molding methods on gel performance, to provide valuable insights into the efficient utilization of plant fibers and the environmentally friendly development of ...
Zhiming Wang +8 more
wiley +1 more source
Advanced Healthcare Materials, EarlyView.A 3D‐printed PCL scaffold coated with Arginine was laminated with electrospun polyvinyl alcohol (PVA) nanofibers containing cationic cellulose nanocrystals (PVA@cCNC). This created nanoisland‐like regions of aligned and random cCNC‐rich fibers. The composite scaffold, under fluid shear stimulation, modulated macrophage polarization from M1 to M2 ...
Keya Ganguly +8 more
wiley +1 more source