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Bacterial bug-out bags: outer membrane vesicles and their proteins and functions

Journal of Microbiology, 2020
Among the major bacterial secretions, outer membrane vesicles (OMVs) are significant and highly functional. The proteins and other biomolecules identified within OMVs provide new insights into the possible functions of OMVs in bacteria. OMVs are rich in proteins, nucleic acids, toxins and virulence factors that play a critical role in bacteria-host ...
Huaxi Xu   +7 more
openaire   +3 more sources

Biogenesis of β-barrel integral proteins of bacterial outer membrane

Biochemistry (Moscow), 2012
Gram-negative bacteria are enveloped by two membranes, the inner (cytoplasmic) (CM) and the outer (OM). The majority of integral outer membrane proteins are arranged in β-barrels of cylindrical shape composed of amphipathic antiparallel β-strands. In bacteria, β-barrel proteins function as water-filled pores, active transporters, enzymes, receptors ...
Tamara F. Solov'eva   +2 more
openaire   +3 more sources

Multiple pathways allow protein secretion across the bacterial outer membrane

Current Opinion in Cell Biology, 2000
Secretion of proteins across the bacterial outer membrane takes place via a variety of mechanisms from simple one-component systems to complex multicomponent pathways. Secretion pathways can be organized into evolutionarily and functionally related groups, which highlight their relationship with organelle biogenesis.
Scott J. Hultgren, David G. Thanassi
openaire   +3 more sources

Outer Membrane Protein OmpB Methylation May Mediate Bacterial Virulence

Trends in Biochemical Sciences, 2017
Methylation of outer membrane proteins (OMPs) has been implicated in bacterial virulence. Lysine methylation in rickettsial OmpB is correlated with rickettsial virulence, and N- and O-methylations are also observed in virulence-relevant OMPs from several pathogenic bacteria that cause typhus, leptospirosis, tuberculosis, and anaplasmosis.
Bok-Eum Choi   +4 more
openaire   +3 more sources

Outer membrane proteins: key players for bacterial adaptation in host niches

Microbes and Infection, 2002
Outer membrane proteins (OMPs) of Gram-negative bacteria have diverse functions and are directly involved in the interaction with various environments encountered by pathogenic organisms. Thus, OMPs represent important virulence factors and play essential roles in bacterial adaptation to host niches, which are usually hostile to invading pathogens ...
Shouxiong Huang, Qijing Zhang, Jun Lin
openaire   +3 more sources

A REVIEW ON THE IMMUNOGENICITY OF FISH PATHOGENIC BACTERIAL OUTER MEMBRANE PROTEINS

Acta Hydrobiologica Sinica, 2011
Songlin Guo   +3 more
openaire   +2 more sources

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