Results 91 to 100 of about 1,616,748 (350)

Can clinical findings at admission allow withholding of antibiotics in patients hospitalized for community acquired pneumonia when a test for a respiratory virus is positive?

Pneumonia
Background Current guidelines recommend empiric antibiotic therapy for patients who require hospitalization for community-acquired pneumonia (CAP). We sought to determine whether clinical, imaging or laboratory features in patients hospitalized for CAP ...
Ryan Ward, Alejandro J. Gonzalez, Justin A. Kahla, Daniel M. Musher   +3 more
doaj   +1 more source

Case‐Based Immunology: B Cells and Systemic Sclerosis Interstitial Lung Disease

Arthritis &Rheumatology, EarlyView.
Interstitial lung disease (ILD) is an important complication of systemic sclerosis (SSc), with high mortality and morbidity. Recent clinical studies in SSc‐ILD have led to US Food and Drug Administration–approved therapies in SSc‐ILD. Importantly, evidence from these studies has been extrapolated to guide management of ILDs of other systemic autoimmune
Nina Goldman, Voon Ong, Christopher P. Denton   +2 more
wiley   +1 more source

CRP/Neopterin Ratio and Neuropsychiatric Symptoms in Patients with Different Forms of Pneumonia: Results of a Pilot Study

Microorganisms
Background: Pneumonia is one of the most common infectious diseases, mostly caused by viruses or bacteria. In response to bacteria or viruses which are different but which also are partly overlapping, innate and adaptive immune responses are induced ...
Katharina Konstanze Lilly Wagner, Daniele Corda, Andreas Steinmayr, Francesco Burkert, Dietmar Fuchs, Johanna Gostner, Stefanie Hofer, Lucia Parrakova, Irina Gasslitter, Günter Weiss, Christian Irsara, Sarah Maier, Andrea Griesmacher, Rosa Bellmann-Weiler, Katharina Kurz   +14 more
doaj   +1 more source

Long‐Term Outcomes of Reduced Intensity Conditioning Hematopoietic Stem Cell Transplantation for Systemic Sclerosis Patients with Impaired Cardiac Function

Arthritis &Rheumatology, Accepted Article.
Objective High intensity conditioning autologous hematopoietic stem cell transplantation (AHSCT) is standard of care for patients with advanced SSc. The role of reduced intensity conditioning (RIC) prior to AHSCT in this population remains unclear. We conducted this study to determine the long‐term outcomes of RIC AHSCT in SSc patients with cardiac ...
Yonatan Lean, Carrie Richardson, Anthony Esposito, Katy Bedjeti, George E. Georges   +4 more
wiley   +1 more source

The mito-DAMP cardiolipin blocks IL-10 production causing persistent inflammation during bacterial pneumonia

Nature Communications, 2017
Bacterial pneumonia is a significant healthcare burden worldwide. Failure to resolve inflammation after infection precipitates lung injury and an increase in morbidity and mortality.
Krishnendu Chakraborty, Mahesh Raundhal, Bill B. Chen, C. Morse, Y. Tyurina, Anupriya Khare, T. Oriss, Rachael Huff, Janet S. Lee, C. S. St Croix, Simon C Watkins, R. Mallampalli, V. Kagan, A. Ray, P. Ray   +14 more
semanticscholar   +1 more source

A systematic scoping review of metrics utilized to measure antibiotic consumption in hospital settings

British Journal of Clinical Pharmacology, EarlyView.
Abstract Antimicrobial stewardship (AMS) programs were introduced to promote the judicious use of antimicrobials and to combat antimicrobial resistance. Quantifying antibiotic consumption is an important part of AMS initiatives to achieve these objectives.
Marjan Kandimahforoujaki, Kiplin A. Patanwala, Jan‐Willem C. Alffenaar, Asad E. Patanwala   +3 more
wiley   +1 more source

Risk of Parkinson’s Disease after a Diagnosis of Bacterial Pneumonia: A Nationwide Longitudinal Follow-up Study

Journal of Medical Sciences
Background: Parkinson’s disease (PD) is receiving increasing attention owing to the possibility of its immense burden on society in the future. The inconsistent findings of previous studies highlight that different pathogens and infection sites may have ...
Chih-Sung Liang, Fu-Chi Yang, Shih-Jen Tsai, Ya-Mei Bai, Chia-Kuang Tsai, Mu-Hong Chen   +5 more
doaj   +1 more source

Measurement of complement receptor 1 on neutrophils in bacterial and viral pneumonia

BMC Infectious Diseases, 2006
Background A reliable prediction of the causative agent of community-acquired pneumonia (CAP) is not possible based on clinical features. Our aim was to test, whether the measurement of the expression of complement receptors or Fcγ receptors on ...
Nikoskelainen Jukka, Laitinen Iina, Lilius Esa-Matti, Nuutila Jari, Hohenthal Ulla, Kotilainen Pirkko   +5 more
doaj   +1 more source

The integration of the British Pharmacological Society's prescription safety assessment into the WHO 6‐step model of rational pharmacotherapy in a Turkish medical school

British Journal of Clinical Pharmacology, EarlyView.
Aims At Koç University School of Medicine, a one‐week rational pharmacotherapy (RPHM) programme, modelled after WHO 6‐step, has been introduced in the fourth‐year curriculum to improve prescription skills. For efficient problem‐based learning (PBL) sessions on a prespecified topic, students need to brush up on basic pharmacology knowledge, so we ...
Sinem Ezgi Gülmez, Gülnihal Özcan, Hakan S. Orer   +2 more
wiley   +1 more source

Effect of vaccination on morbidity and mortality from community-acquired pneumonia

Acta Biomedica Scientifica
Background. Community-acquired pneumonia remains one of the most common and life-threatening forms of pathology among respiratory diseases.The aim of the study. To identify the features of the epidemiology of communityacquired pneumonia in the conditions
T. A. Bayanova, E. S. Stukova, N. A. Kravchenko   +2 more
doaj   +1 more source