Results 81 to 90 of about 1,816,488 (304)

A novel mouse model of chronic Pseudomonas aeruginosa infection inducing bronchiectasis‐like phenotype

Animal Models and Experimental Medicine, EarlyView.
This graphical abstract highlights a bronchiectasis mouse model driven by chronic Pseudomonas aeruginosa (CPA)‐loaded agar beads plus papain, which reproduces significant airway structural damage, inflammation, mucous overproduction, and functional impairment, providing a clinically relevant platform for studying disease mechanisms and evaluating ...
Heng Yang, Yang Liu, Yuqing Wang, Yuhua Wen, Yan Chen, Rui Fan, Jiayan Xu, Shunlian Hu, Hao Qian, Rui Jiang, Weijun Cao, Jinfu Xu   +11 more
wiley   +1 more source

Diagnostic and prognostic value of serum HBP combined with PCT, CRP, and SAA in early-stage pneumonia

Virology Journal
Objective To assess the diagnostic efficacy of serum heparin-binding protein (HBP) as a standalone biomarker and in combination panels for distinguishing early-stage bacterial from viral pneumonia, and to explore its prognostic value in predicting ...
Pengju Cao, Songgao Zhang, Jiangang Huang, Wanru Dai   +3 more
doaj   +1 more source

Immune persistence of a single dose of 23-valent pneumococcal polysaccharide vaccine: A 6-year follow-up

Human Vaccines & Immunotherapeutics
In a previous phase 3 clinical trial, a 23-valent pneumococcal polysaccharide vaccine (PPV23) induced robust immune responses in participants aged 2 years and older.
Lili Huang, Xinyi Yang, Hong Li, Zhiqiang Xie, Taotao Zhu, Wangyang You, Zeng Wang, Jiebing Tan, Guangwei Feng, Qingmin Sun, Bin Wang, Xing Han, Yanxia Wang   +12 more
doaj   +1 more source

Clinical and Etiological Features of Community-acquired Pneumonia in Children in Vladivostok

Детские инфекции (Москва), 2015
A survey of 991 with community-acquired pneumonia. The disease is most proceeded in the average severity (97.2 %). In 99.4 % of cases diagnosed focal, polysegmental pneumonia in 0.6% of cases.
L. G. Erokhina, O. G. Savina, T. O. Svirinkova, M. A. Terpugova   +3 more
doaj   +1 more source

Green Fuel Combustion Synthesis of CeO2 and Ag/CeO2 Nanoparticles for Photocatalytic and Antibacterial Applications

Asia-Pacific Journal of Chemical Engineering, EarlyView.
ABSTRACT Silver‐doped cerium oxide nanoparticles (Ag/CeO2 NPs) were synthesized using Ricinus communis seed extract as a bio‐derived fuel in a solution combustion method. The combustion reaction, carried out at 450°C with AgNO3 and (NH4)2[Ce (NO3)6] as metal precursors, produced CeO2 and Ag/CeO2 NPs.
T. N. Ravishankar, J. R. Adarsha, R. Mohan Reddy, S. Harisha, A. Ananda, B. M. Shilpa   +5 more
wiley   +1 more source

Neutrophil-lymphocyte ratio as a point-of-care marker for predicting bacterial etiology in pediatric community-acquired Pneumonia: A comparative analysis with C -reactive protein

Clinical Epidemiology and Global Health
Objectives: To evaluate the role of NLR in predicting bacterial etiology in pediatric community acquired pneumonia and compare its diagnostic performance with CRP.
Maya Lakshmanan, Sandeep Kumar, Sowmya Shashidhara, Pushpa Kini, Shrikiran Aroor, Suneel Mundkur, Ramesh Bhat Y, Karen Moras   +7 more
doaj   +1 more source

Pneumonia hospitalizations of children aged <2 years in Poland before (2013–2016) and after (2017–2018) universal mass vaccination with 10-valent pneumococcal non-typeable Haemophilus influenzae protein D conjugate vaccine

Human Vaccines & Immunotherapeutics, 2022
As infection with Streptococcus pneumoniae is an important cause of pneumonia in children, the World Health Organization recommends childhood pneumococcal conjugate vaccines (PCVs).
Amit Bhavsar, Janusz Zaryczański, Anna Wasilewska, Delphine Saragoussi, Raghavendra Devadiga, Chris Colby, Enas Bahar, Jacek Wysocki   +7 more
doaj   +1 more source

Bystander Activation of Pulmonary Trm Cells Attenuates the Severity of Bacterial Pneumonia by Enhancing Neutrophil Recruitment.

Cell Reports, 2019
Tissue-resident memory T (Trm) cells are described as having a "sensing and alarming" function, meaning they can rapidly release cytokines in response to local cognate antigen recognition, which in turn, draws circulating immune cells into the tissue ...
Chenghao Ge, I. Monk, A. Pizzolla, Nancy Wang, James G. Bedford, T. Stinear, G. Westall, L. Wakim   +7 more
semanticscholar   +1 more source

Integrating One Health to Mitigate the Emergence and Spread of Antimicrobial Resistance in Livestock and Aquaculture

Animal Research and One Health, EarlyView.
Antimicrobial resistance (AMR) is an escalating global threat driven by antimicrobial use in aquaculture and livestock. Resistant pathogens and genes can spread across humans, animals, and the environment through interconnected ecosystems. Using a One Health approach, this review emphasizes antimicrobial stewardship, regulatory strengthening, enhanced ...
Mir Mohammad Ali, Delower Hossain, Ridwan Olamilekan Adesola, Anum Hanif, Shamsaldeen Ibrahim Saeed, Muhammad Abdul Mannan, Anoar Jamai Masroure, Kazi Estieque Alam, Md Kamal Hossain, Sabiha Zarin Tasnim Bristi, Md Jisan Ahmed   +10 more
wiley   +1 more source

Integrated Clinical and Proteomic Profiling of CD19 Chimeric Antigen Receptor T Cell Therapy in Progressive Systemic Sclerosis

Arthritis &Rheumatology, EarlyView.
Objective To characterize the clinical, immunologic, and proteomic changes associated with CD19 chimeric antigen receptor T cell therapy in patients with progressive systemic sclerosis (SSc). Methods Patients with progressive SSc received CD19 chimeric antigen receptor (CAR)‐T cell therapy and were observed longitudinally for safety, clinical efficacy,
Chenhan Jia, Wanyi Lin, Zhangyi Zhao, Fenglin Wu, Chaoyu Gu, Yuankai Sun, Zhe Ding, Chang Wei, Xinyu Li, Cuiwei Xie, Peng Xia, Zhen Xia, Xuesong Liu, Shaoying Yang, Chunyan Zhang, Hanlin Yin, Liangjing Lu   +16 more
wiley   +1 more source