Results 51 to 60 of about 1,206,208 (293)

Fungal pneumonia concealing bacterial pneumonia: a diagnostic dilemma

Monaldi Archives for Chest Disease, 2023
We describe the case of a 61-year-old diabetic man affected by Achromobacter denitrificans. He was immunocompetent and did not have any past history of chronic lung disease.
Christie George Joseph, Madhusmita Mohanty Mohapatra, Manju Rajaram, Jayabharathi Palanivel, Balasubramanian Velappan   +4 more
doaj   +1 more source

Target product profile for a diagnostic assay to differentiate between bacterial and non-bacterial infections and reduce antimicrobial overuse in resource-limited settings: an expert consensus [PDF]

, 2016
Acute fever is one of the most common presenting symptoms globally. In order to reduce the empiric use of antimicrobial drugs and improve outcomes, it is essential to improve diagnostic capabilities.
Zorzet, A., Tadesse, BT, Paul N Newton, Newton, P.N., Quique Bassat (89288), Lubell, Yoel,, Zorzet, Anna, D'Acremont, Valerie,, Bassat, Quique,, Norbert Heinrich, Crump, John A.,, Paul N. Newton (132889), Yoel Lubell, Zorzet, A, Valerie D’Acremont (3079494), Dolinger, D.L., Anna Zorzet, Anna Zorzet (3079506), Newton, PN, Iveth J. González (137011), Chua, Arlene,, Rodwell, T.J., D'Acremont, V., González, Iveth J, David L Dolinger, Heinrich, Norbert,, Dittrich, Sabine, Dittrich, S, Gonzalez, Iveth J.,, Rodwell, Timothy J.,, González, I.J., Norbert Heinrich (175590), Tängdén, Thomas,, Page, A.L., Chua, A., Dolinger, David L., Dolinger, David L, John A. Crump (231237), Tilahun, Birkneh Tilahun, Thomas Tängdén, Newton, Paul, Birkneh Tilahun Tadesse, Lubell, Y, Francis Moussy, Timothy J Rodwell, Bassat, Quique, Newton, Paul N.,, Tängdén, T., Tadesse, Birkneh Tilahun,, Thomas Tängdén (3079503), Arlene Chua, Moussy, F, Moussy, F., Rodwell, Timothy J., Page, Anne-Laure, Lubell, Yoel, Tadesse, B.T., Bassat Orellana, Quique, Valerie D'Acremont, Birkneh Tilahun Tadesse (769116), Crump, John A., Bassat, Q, John A Crump, Chua, A, Newton, Paul N., Bassat, Q., Acremont, Valerie D’, González, Iveth J., Sabine Dittrich (85996), Tängdén, Thomas, Newton, Paul N, David L. Dolinger (3079500), Page, Anne-Laure, Moussy, Francis, Anne-Laure Page, Crump, J.A., Rodwell, Timothy J, Crump, JA, Tadesse, Birkneh Tilahun, Timothy J. Rodwell (3079497), Iveth J González, González, IJ, Chua, Arlene, Zorzet, Anna,, Heinrich, N, Dittrich, S., Yoel Lubell (88683), Page, Anne-Laure,, Page, AL, D'Acremont, Valerie, Dolinger, David L.,, Heinrich, N., Tängdén, T, Crump, John A, Heinrich, Norbert, Dittrich, Sabine,, Arlene Chua (134856), Sabine Dittrich, Dolinger, DL, Anne-Laure Page (247439), D'Acremont, V, Rodwell, TJ, Moussy, Francis,, Quique Bassat, Lubell, Y., Francis Moussy (127840)   +105 more
core   +1 more source

Hydrogels Augmented With Artificial Sweeteners can Inhibit Multidrug‐Resistant Acinetobacter baumannii Growth and Biofilm Formation While Demonstrating Safety in Pre‐Clinical Pilot Human Trials

Advanced Healthcare Materials, EarlyView.
Using PVA–borax hydrogels as carriers for off‐the‐shelf artificial sweeteners to fight multidrug‐resistant A. baumannii. These soft, biocompatible hydrogels rapidly reduce bacterial viability within multidrug‐resistant A. baumannii biofilms by more than 99% within one hour and sustain antimicrobial activity over time, while demonstrating safety in both
Jie Han, Mohamed Soliman, Bin Zhang, Dominika Krawiel, Ronan R. McCarthy   +4 more
wiley   +1 more source

Immune persistence of a single dose of 23-valent pneumococcal polysaccharide vaccine: A 6-year follow-up

Human Vaccines & Immunotherapeutics
In a previous phase 3 clinical trial, a 23-valent pneumococcal polysaccharide vaccine (PPV23) induced robust immune responses in participants aged 2 years and older.
Lili Huang, Xinyi Yang, Hong Li, Zhiqiang Xie, Taotao Zhu, Wangyang You, Zeng Wang, Jiebing Tan, Guangwei Feng, Qingmin Sun, Bin Wang, Xing Han, Yanxia Wang   +12 more
doaj   +1 more source

Electrospun Core–Shell Bioadhesive Nanofiber Sheets Enable Durable Pulmonary Air Leak Sealing Under Wet and Dynamic Conditions

Advanced Healthcare Materials, EarlyView.
A core–shell electrospun nanofiber sheet provides strong adhesion and durable sealing on the wet and dynamic lung surface. The engineered fibrous architecture maintains airtight integrity and offers a potential alternative to fibrin sealants for pulmonary air leak management in thoracic surgery.
Tomohito Okubo, Kouji Hara, Naoyuki Hatayama, Kota Takahashi, Eriko Yamazoe, Takaaki Ito, Takao Takeuchi, Yoko Koide, Mayumi Yamada, Munekazu Naito, Kohei Tahara   +10 more
wiley   +1 more source

A comparison of demographic, epidemiological and clinical characteristics of hospital influenza-related viral pneumonia patients

BMC Infectious Diseases, 2021
Background Through the comparison of the demographic, epidemiological, and clinical characteristics of hospital human influenza (influenza A (H1N1) pdm09, H3N2, and B)-related and hospitalized avian-origin influenza A (H7N9)-related viral pneumonia ...
Bin Fu, Zhengjie Wu, Lingtong Huang, Zhaohui Chai, Peidong Zheng, Qinmiao Sun, Silan Gu, Qiaomai Xu, Haiting Feng, Lingling Tang   +9 more
doaj   +1 more source

Lactiplantibacillus Plantarum GUANKE Alleviates Allergic Asthma by Restricting Monocyte‐to‐DC Differentiation Via Microbiota‐Associated IAA

Advanced Science, EarlyView.
Lactiplantibacillus plantarum GUANKE remodels the indigenous gut microbiota and is associated with microbiota‐dependent restoration of circulating IAA. IAA treatment attenuates JAK3‐STAT3 and Jag1‐Notch4‐Hey1 signaling and reduces CX3CR1+Ly6C− monocytic precursor generation and pulmonary CD11b+ DC accumulation, together with reduced Th2 inflammation ...
Yujia He, Jielan Mi, Zhiping Zhao, Xiao Zhang, Zhihan Yang, Kun Yue, Yuanming Huang, Liqiong Song, Xiaoting Wen, Jianguo Xu, Zhihong Ren   +10 more
wiley   +1 more source

Potential use of serum based quantitative real-time PCR for the detection of pneumonia pathogens in a densely colonised population [PDF]

, 2012
Molecular methods offer improvement in the detection of causative pneumonia pathogens, but there are concerns of false positive results. Here we validate quantitative real-time PCR (qPCR) assays for the detection of Streptococcus pneumoniae and ...
Binks, Michael J, Smith-Vaughan, Heidi C, Leach, Amanda J, Kaestli, Mirjam, Lai, Jana YR   +4 more
core   +1 more source

Engineering Microbial Particles for Next‐Generation Biomedical Platforms

Advanced Science, EarlyView.
Microbe‐derived particles (MDPs), which include extracellular vesicles, outer membrane vesicles, inclusion bodies, polysaccharide particles, and virus‐like particles, represent a rapidly expanding category of bioinspired nanomaterials. With their natural origin, intrinsic biocompatibility, and highly programmable functionality, MDPs serve as a ...
Yuting Li, Yunjie Lu, Ziyan Huang, Jianjiang Chen, Yanbin Liu, Lei Qin, Chao Wang, Yumin Wu   +7 more
wiley   +1 more source

Assessment of nasopharyngeal Streptococcus pneumoniae colonization does not permit discrimination between Canadian children with viral and bacterial respiratory infection: a matched-cohort cross-sectional study

BMC Infectious Diseases, 2021
Background Readily-available diagnostics do not reliably discriminate between viral and bacterial pediatric uncomplicated pneumonia, both of which are common.
Jeffrey M. Pernica, Kristin Inch, Haifa Alfaraidi, Ania Van Meer, Redjana Carciumaru, Kathy Luinstra, Marek Smieja   +6 more
doaj   +1 more source