Results 41 to 50 of about 1,206,208 (293)

Treating childhood pneumonia in hard-to-reach areas: a model-based comparison of mobile clinics and community-based care. [PDF]

, 2012
BACKGROUND: Where hard-to-access populations (such as those living in insecure areas) lack access to basic health services, relief agencies, donors, and ministries of health face a dilemma in selecting the most effective intervention strategy. This paper
Francesco Checchi, Roberts Bayard, Roberts, Bayard, Pitt, Catherine, Checchi Francesco, Checchi, Francesco, Pitt Catherine, Catherine Pitt, Bayard Roberts   +8 more
core   +2 more sources

Comparison of Short- versus Long-Course Antimicrobial Therapy of Uncomplicated Bacterial Pneumonia in Dogs: A Double-Blinded, Placebo-Controlled Pilot Study

Animals, 2021
Current treatment for canine bacterial pneumonia relies on protracted courses of antimicrobials (3–6 weeks or more) with recommendations to continue for 1–2 weeks past resolution of all clinical and thoracic radiographic abnormalities. However, in humans,
Aida I. Vientós-Plotts, Isabelle Masseau, Carol R. Reinero   +2 more
doaj   +1 more source

ANTIBIOTIC STEWARDSHIP STRATEGIES TO LIMIT INAPPROPRIATE ANTIBIOTIC USE AND REDUCE MULTI-DRUG RESISTANT PATHOGENS DURING COVID-19 PANDEMIC

International Journal of Infectious Diseases, 2023
Antibiotics have been extensively used in COVID-19 patients without a clear indication. COVID-19 pneumonia is associated with a mortality up to 20% varying by country with the number of global deaths over 5 million. Antibiotics have been extensively used
Anucha Apisarnthanarak
doaj   +1 more source

Comparative Effectiveness and Safety of Inebilizumab Versus Rituximab in AQP4‐IgG‐Positive NMOSD

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Rituximab (anti‐CD20, RTX) and inebilizumab (anti‐CD19, INE) represent B‐cell‐depleting therapies used for aquaporin‐4 antibody‐positive (AQP4‐IgG+) neuromyelitis optica spectrum disorder (NMOSD); however, direct comparative evidence remains limited.
Jie Lin, Binbin Xue, Dewei Xie, Jia Li, Juyuan Pan, Lanbing Zhu, Qiaowen Tong, Jing Lin, Ruofan Zhu, Xu Zhang, Junhui Xia, Xiang Li   +11 more
wiley   +1 more source

Decreasing incidence and determinants of Bacterial Pneumonia in people with HIV: The Swiss HIV Cohort Study [PDF]

, 2022
BACKGROUND Bacterial pneumonia is one of the leading reasons for hospitalization among people with HIV (PWH), yet there is limited evidence regarding its drivers in the era of potent antiretroviral therapy.
Battegay, Manuel, Calmy, A., Hauser, C., Günthard, Huldrych F, Roth, J.A., Cavassini, M., Battegay, M., Balakrishna, S., Calmy, Alexandra, Bernasconi, Enos, Balakrishna, Suraj, Kachalov, Viacheslav, Swiss HIV Cohort Study, Schmid, Patrick, Kouyos, Roger D, Furrer, Hansjakob, Wolfensberger, Aline, Kusejko, K., Schmid, P., Furrer, H., Kouyos, R.D., Kachalov, V., Scherrer, A.U., Günthard, H.F., Roth, Jan A, Cavassini, Matthias; https://orcid.org/, Kusejko, Katharina, Scherrer, Alexandra U, Hauser, Christoph, Wolfensberger, A., Cavassini, Matthias, Bernasconi, E.   +31 more
core   +2 more sources

Incidence, Risk Factors and Management of Adverse Events in Contemporary Real‐World Care of Children with Juvenile Idiopathic Arthritis

Arthritis Care &Research, Accepted Article.
Objective We describe the frequency, risk factors, severity, and management of actionable and serious adverse events (AAE and SAE) in children with newly diagnosed Juvenile Idiopathic Arthritis (JIA) in Canada. Methods We enrolled patients within 3 months of JIA diagnosis in the Canadian Alliance of Pediatric Rheumatology Investigators (CAPRI) Registry,
Bashayer Alnuaimi, Roberta A. Berard, Jean‐Philippe Proulx‐Gauthier, Heinrike Schmeling, Michelle Batthish, Gilles Boire, Adam M. Huber, Dax G. Rumsey, Jaime Guzman, Gaëlle Chédeville, The CAPRI registry Investigators   +10 more
wiley   +1 more source

Accuracy of the diagnosis of pneumonia in Canadian pediatric emergency departments: A prospective cohort study.

PLoS ONE
BackgroundThe diagnosis of pediatric pneumonia and determination of the likely pathogen are complicated as the clinical picture overlaps with other respiratory illnesses, interpretation of radiographs is subjective, and laboratory results are rarely ...
Joan L Robinson, James D Kellner, Jennifer Crotts, Gabino Travassos, Guanmin Chen, Valerie G Kirk, Martin Pusic, Martin Reed, Sarah Reid, Michael Weinstein, Ravi Bhargava, Maala Bhatt, Kathy Boutis, Sarah Curtis, Serge Gouin, Tim Lynch, Richard van Wylick, David W Johnson   +17 more
doaj   +1 more source

Recombinant plants provide a new approach to the production of bacterial polysaccharide for vaccines. [PDF]

, 2014
Bacterial polysaccharides have numerous clinical or industrial uses. Recombinant plants could offer the possibility of producing bacterial polysaccharides on a large scale and free of contaminating bacterial toxins and antigens.
G. C. Whitelam (7665758), Marie Goldrick (324989), Roberts Ian S., Garry C. Whitelam (519301), Andrew, PW, Patel, Alexandra J.F., Whitelam, Garry C, Claire M. Smith (7665743), Peter W. Andrew (153608), Roberts, Ian S, Whitelam, Garry C., Patel Alexandra J. F., Roberts, IS, K. C. Gough (7665749), Glenn, S, Gough Kevin C., Andrew, Peter W, S. C. Fry (7665746), Alexandra J F Patel, Stephen C Fry, Garry C Whitelam, Kevin C Gough, Gough, KC, Sarah Glenn (519300), Fry Stephen C., Andrew Peter W., Gough, Kevin C, Whitelam, GC, Sarah Glenn, Fry, Stephen C., Claire M. Smith (519296), Roberts, Ian S., Ian S. Roberts (159693), Whitelam Garry C., Peter W Andrew, Smith, Claire M, Patel, Alexandra J F, Patel, AJ, Fry, Stephen C, Stephen C. Fry (519297), Andrew, Peter W., Kevin C. Gough (519298), Ian S Roberts, Fry, SC, Goldrick, M, Smith Claire M., Alexandra J. F. Patel (519299), Goldrick Marie, Marie Goldrick, M. Goldrick (7665755), Goldrick, Marie, Alexandra J. F. Patel (7665752), Gough, Kevin C., Glenn, Sarah, Glenn Sarah, Smith, Claire M., Claire M Smith, Smith, CM, I. S. Roberts (6341096)   +58 more
core   +1 more source

Real‐World Effectiveness and Safety of Secukinumab in Giant Cell Arteritis: An Italian Multicenter Cohort Study

Arthritis Care &Research, EarlyView.
Objective The objective of this study was to evaluate the real‐world effectiveness and safety of secukinumab in patients with giant cell arteritis (GCA). Methods This multicenter retrospective study included patients with GCA who received secukinumab at 14 Italian centers with at least six months of follow‐up.
Luca Iorio, Federica Davanzo, Caterina Ricordi, Milena Bond, Ruggiero Mascolo, Jacopo Mora, Alessandro Tomelleri, Angelo Fassio, Francesca Cuzzocrea, Sara Monti, Edoardo Conticini, Fabiola Atzeni, Paolo Delvino, Carlotta Nannini, Augusta Ortolan, Francesco Pollastri, Ester Vivaldelli, Chiara Marvisi, Paola Toniati, Antonio Brucato, Alessandra Milanesi, Francesca Regola, Enrico Tombetti, Lorenzo Dagna, Roberta Ramonda, Christian Dejaco, Luca Quartuccio, Carlo Salvarani, Roberto Padoan   +28 more
wiley   +1 more source

Dynamically Actuated Reconfigurable Topographical Surface Enables Active Control of Implant‐Associated Infections

Advanced Functional Materials, EarlyView.
A dynamically actuated reconfigurable topographical surface (DARTS) integrates contact‐mediated bactericidal nanotopography with programmable mechanical actuation to actively disrupt bacterial biofilms. Dynamic surface reconfiguration enhances bacterial killing and suppresses implant‐associated infections in vivo, providing a new strategy for active ...
Mohammad Asadi Tokmedash, Jihun Lee, J. Scott VanEpps, Sungmin Nam, Jouha Min   +4 more
wiley   +1 more source