Biomaterial Strategies for Targeted Intracellular Delivery to Phagocytes
Phagocytes are essential to a functional immune system, and their behavior defines disease outcomes. Engineered particles offer a strategic opportunity to target phagocytes, harnessing inflammatory modulation in disease. By tuning features like size, shape, and surface, these systems can modulate immune responses and improve targeted treatment for a ...
Kaitlyn E. Woodworth+2 more
wiley +1 more source
Proteome-wide protein interaction measurements of bacterial proteins of unknown function
Matthias Meier, R. Sit, S. Quake
semanticscholar +1 more source
This study presents an injectable hydrogel that responds to Pseudomonas aeruginosa infection by releasing a dual‐phage cocktail on demand. The system degrades selectively in infected wounds, enhances phage localization and stability, and shows potent antibiofilm activity and biocompatibility in an ex vivo human skin model—offering a promising strategy ...
Siyuan Tao+9 more
wiley +1 more source
The bacterial-type taxis and protein methylation in diatoms [PDF]
E.Kh. Dibrova+3 more
openalex +2 more sources
The "DDVF" motif used by viral and bacterial proteins to hijack RSK kinases mimics a short linear motif (SLiM) found in proteins related to the RAS-ERK MAP kinase pathway. [PDF]
Veinstein M+4 more
europepmc +1 more source
C 55 -Isoprenoid Alcohol Phosphokinase: An Extremely Hydrophobic Protein from the Bacterial Membrane
Heinrich Sandermann, Jack L. Strominger
openalex +1 more source
Demodex‐associated bacterial proteins induce neutrophil activation
N. O’Reilly+4 more
semanticscholar +1 more source
Lanthanide ytterbium ions are introduced into Bi2WO6 nanosheets to boost ROS generation under US stimulation. These ytterbium‐doped Bi2WO6 nanosheets serve as efficient sonosensitizers, enabling broad‐spectrum bacterial eradication. To improve biocompatibility for in vivo sonodynamic therapy, the sonosensitizers are integrated into hydrogel matrix ...
Xinyue Lao+6 more
wiley +1 more source
Interaction between two essential, conserved bacterial proteins YeaZ and glycoprotease as a potential antibacterial target in multi-drug-resistant Staphylococcus aureus. [PDF]
Britton TA, Guo H, Ji Y.
europepmc +1 more source