Results 221 to 230 of about 1,338,778 (300)

Bacterial proteins pinpoint a single eukaryotic root. [PDF]

Proc Natl Acad Sci U S A, 2015
Derelle R, Torruella G, Klimeš V, Brinkmann H, Kim E, Vlček Č, Lang BF, Eliáš M.   +7 more
europepmc   +1 more source

Efficacy and Safety Assessment of 5‐Fluorouracil, Irinotecan and Oxaliplatin‐Loaded Implants in Mouse and Pig Models for Pancreatic Cancer Therapy

Advanced Materials, EarlyView.
A novel FIRINOX‐loaded implant demonstrates controlled drug release, and potent therapeutic efficacy in pancreatic ductal adenocarcinoma mouse models with safety confirmed in a large‐animal pre‐clinical model. This innovative drug delivery platform offers a promising new treatment approach for non‐resectable, treatment‐resistant pancreatic cancer ...
Samantha J. Wade, Ashna A. Kumar, Samuel O. Nitschke, Paul Joyce, Elahe Minaei, Stephanie E. Reuter, Chelsea Penney, Holly Warren, Ruby Shepherd, Jeremy N. Dinoro, Gordon G. Wallace, Anthony Dosseto, Sameera Ansar, Naila Islam, Alistair Lochhead, George Sharbeen, Phoebe A. Phillips, Morteza Aghmesheh, Wayne J. Hawthorne, Kara L. Vine‐Perrow   +19 more
wiley   +1 more source

Bacterial proteins and peptides in cancer therapy: today and tomorrow. [PDF]

Bioengineered, 2014
Chakrabarty AM, Bernardes N, Fialho AM.
europepmc   +1 more source

Hierarchically Engineered Multi‐Enzyme Nanoreactors for in vitro Drug Biosynthesis and Pathway Transplantation Into Cells

Advanced Materials, EarlyView.
A hierarchically structured metal–organic framework (eMIL) is shown to host the complete six‐enzyme biosynthesis pathway for the anti‐cancer pigment violacein, reshaping reaction dynamics and multiplying in vitro yields. eMIL nanoreactors deliver this reconstituted bacterial multi‐protein system into mammalian cells, where cell‐derived substrates and ...
Ainur Sharip, Somayah S. Qutub, Manar M. Farooqui, Walaa Baslyman, Nida Khalfay, Lukman O. Alimi, Patricia Lopez Sanchez, Lingyun Zhao, Milena Chernyshevskaia, Giovanni Colombo, Niveen M. Khashab, Stefan T. Arold, Raik Grünberg   +12 more
wiley   +1 more source

Azithromycin Attenuates Pseudomonas-Induced Lung Inflammation by Targeting Bacterial Proteins Secreted in the Cultured Medium. [PDF]

Front Immunol, 2016
Leal T, Bergamini G, Huaux F, Panin N, Noel S, Dhooghe B, Haaf JB, Mauri P, Motta S, Di Silvestre D, Melotti P, Sorio C.   +11 more
europepmc   +1 more source

Leaftronics: Bio‐Fractal Scaffolds From Leaf Venation for Low‐Waste Electronics

Advanced Materials, EarlyView.
“Leaftronics” transforms naturally evolved leaf venation into quasi‐fractal scaffolds for sustainable electronics. Polymer‐infiltrated leaf skeletons can be used to fabricate ultra‐smooth, reflow‐ and thin‐film‐compatible decomposable substrates, while making the same lignocellulose networks conducting results in flexible transparent electrodes.
Rakesh Rajendran Nair, Hrisheekesh Thachoth Chandran, Karl Leo, Hans Kleemann   +3 more
wiley   +1 more source

AI–Guided 4D Printing of Carnivorous Plants–Inspired Microneedles for Accelerated Wound Healing

Advanced Materials, EarlyView.
This work presents an artificial intelligence (AI)‐guided 4D‐printed microneedle platform inspired by carnivorous plants for wound healing. A thermo‐responsive shape memory polymer enables body temperature–triggered self‐coiling for autonomous wound closure.
Hyun Lee, Moon‐Jo Kim, DongEung Kim, Chan Ho Moon, Seojoon Bang, Hyeong Seok Kang, Ju Yeong Gwon, Jong Hwa Seo, Junhyub Jeon, Junhyuk Son, Munwon Lim, Minho Kang, Dong Yun Lee, Donghyun Lim, Jung‐Hoon Park, Gi Doo Cha, Soo‐Hong Lee, Tae‐Sik Jang, Kisuk Yang, Yunho Jeong, Youngho Eom, Hyun‐Do Jung   +21 more
wiley   +1 more source

Autonomous Cargo Transport with Biohybrid Microswimmers Enabled by Light‐Mediated Bacteria‐Cargo Communication

Advanced Materials, EarlyView.
ABSTRACT Biohybrid microswimmers, which integrate the unique mobility and taxis of living cells with the versatility of synthetic cargo, offer exciting opportunities for targeted delivery. However, current biohybrids lack autonomous decision‐making capabilities due to the absence of communication between living and synthetic components. Here, we report
Xiaoran Zheng, Yanjun Zheng, Ali Heidari, Seraphine V. Wegner   +3 more
wiley   +1 more source

Characterization and Antimicrobial Activity of Hafnium Nanostructures Fabricated by Physical Vapor Deposition Through a Colloidal Mask

Advanced Materials Interfaces, EarlyView.
We generate hafnium nanostructures by first depositing polystyrene particles of varying diameter followed by physical vapour deposition of hafnium thin films. The resultant structure shows a kill‐on‐contact effect against both Gram‐negative Escherichia coli and Gram‐positive Staphylococcus aureus.
Andrew Boden, Tzu‐Ying Liao, Tomas Katkus, Helmut Thissen, De Ming Zhu, Mrinal Bhave, Peter Kingshott   +6 more
wiley   +1 more source

Formyl-methionine as a degradation signal at the N-termini of bacterial proteins. [PDF]

Microb Cell, 2015
Piatkov KI, Vu TT, Hwang CS, Varshavsky A.   +3 more
europepmc   +1 more source