Results 81 to 90 of about 160,303 (300)

Genome and pan-genome analysis to classify emerging bacteria

open access: yesBiology Direct, 2019
Background In the recent years, genomic and pan-genomic studies have become increasingly important. Culturomics allows to study human microbiota through the use of different culture conditions, coupled with a method of rapid identification by MALDI-TOF ...
Aurélia Caputo   +2 more
doaj   +1 more source

Molecular Characterisation of Bacteriophage K Towards Applications for the Biocontrol of Pathogenic Staphylococci [PDF]

open access: yes, 2006
End of project reportThe aim of this work was to characterise staphylococcal bacteriophage (a bacterial virus) and to assess their potential as therapeutic agents against pathogenic strains of Staphylococcus aureus, particularly mastitis-causing strains.
Coffey, Aidan   +5 more
core  

Inulin‐Based Oral Chemotherapy Modulates Gut Microbiota and Immune Microenvironment through Inhibition of Neutrophil Extracellular Trap Formation for Improving Cancer Therapy

open access: yesAdvanced Science, EarlyView.
Schematic representation of ZIF‐8@OXA@inulin for cancer immunotherapy. Synthesis of ZIF‐8@OXA@inulin. Augmentation of pyroptosis, regulation of gut microbiota, and inhibition of NETs formation by ZIF‐8@OXA@inulin‐mediated comprehensive strategy for antitumor immune response. ABSTRACT Despite the potential of chemoimmunotherapy against colorectal cancer
Zhenhao Li   +8 more
wiley   +1 more source

Pseudomonas Isolation and Identification: An Introduction to the Challenges of Polyphasic Taxonomy

open access: yesJournal of Microbiology & Biology Education, 2014
The ability to isolate an organism in pure culture from the environment is a manageable task for undergraduate students; the identification of that organism requires integration of both genotypic and phenotypic data and illustrates the challenges ...
Kathleen Sandman, Christopher Ecker
doaj   +1 more source

Discordant transmission of bacteria and viruses from mothers to babies at birth [PDF]

open access: yes, 2019
BACKGROUND: The earliest microbial colonizers of the human gut can have life-long consequences for their hosts. Precisely how the neonatal gut bacterial microbiome and virome are initially populated is not well understood.
Handley, Scott A   +8 more
core   +2 more sources

Programmable Klebsiella pneumoniae Phage Tropism Enabled by Scalable Receptor‐Binding Protein Mining and Modular Assembly

open access: yesAdvanced Science, EarlyView.
This work introduces a scalable, data‐driven strategy that turns the vast sequence diversity of phage receptor‐binding proteins into modular tools for engineering customizable phages. By clustering and experimentally validating diverse RBPs, the authors build an accurate map linking sequence to host specificity and create plug‐and‐play modules that ...
Shisong Jing   +10 more
wiley   +1 more source

The Human Oral Microbiome Database: a web accessible resource for investigating oral microbe taxonomic and genomic information [PDF]

open access: yes, 2010
The human oral microbiome is the most studied human microflora, but 53% of the species have not yet been validly named and 35% remain uncultivated. The uncultivated taxa are known primarily from 16S rRNA sequence information.
Baranova, Oxana V.   +5 more
core   +1 more source

Time‐Controlled Refrigerated Stem Cell Therapy Mitigates Scleroderma Fibrosis via Modulation of Mitochondrial Autophagy and Gut Metabolism

open access: yesAdvanced Science, EarlyView.
This study established an RT‐MSCs‐based therapeutic approach for scleroderma in mice. RT‐MSCs attenuated fibrosis by regulating mitochondrial autophagy and restored gut microbiota homeostasis. Metabolomic analyses confirmed recovery of key metabolites, and RT‐MSCs demonstrated favorable lesion targeting and safety profiles.
Xue Xia   +5 more
wiley   +1 more source

Actinopolyspora saharensis sp. nov., a novel halophilic actinomycete isolated from a Saharan soil of Algeria [PDF]

open access: yes, 2012
A novel halophilic actinomycete, strain H32T,was isolated froma Saharan soil sample collected in El-Oued province, south Algeria. The isolate was characterized by means of polyphasic taxonomy. Optimal growth was determined to occur at 28–32°C, pH 6.0–7.0
Bouras, Noureddine   +8 more
core   +3 more sources

Principles and Practice of Bacterial Taxonomy--a Forward Look [PDF]

open access: yesJournal of General Microbiology, 1965
Taxonomy is divisible into three parts: (1) classification, (2) nomenclature, (3) identification. There are rules of nomenclature but none for classification or identification. Six principles are postulated for classification of bacteria and three ways of making identifications are discussed.
openaire   +2 more sources

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