Results 171 to 180 of about 1,432,377 (335)

Rod‐shaped Polymerized Salicylic Acid Particles Modulate Neutrophil Transendothelial Migration in Acute Inflammation

Advanced Healthcare Materials, EarlyView.
Rod‐shaped particles outperform spherical particles of the same volume in preventing neutrophil infiltration to inflamed areas, both in vitro and in vivo. This therapeutic effectiveness is attributed to better cell targeting and decreased cell motility, resulting from the geometry‐driven phagocytosis and inhibited actin polymerization.
M. Valentina Guevara, Emma R. Brannon, Daniel Kupor, Mariana R.N. Lima, Logan D. Piegols, Michael L. Felder, Kathryn E. Uhrich, Omolola Eniola‐Adefeso   +7 more
wiley   +1 more source

Quantitative Analysis of Bacterial Toxin Affinity and Specificity for Glycolipid Receptors by Surface Plasmon Resonance [PDF]

, 1997
Catherine Mackenzie, Tomoko Hirama, Kok K. Lee, Eleonora Altman, N. Martin Young   +4 more
openalex   +1 more source

Organoid‐Like Neurovascular Spheroids Promote the Recovery of Hypoxic‐Ischemic Skin Flaps Through the Activation of Autophagy

Advanced Healthcare Materials, EarlyView.
Highly sprouting organoid‐like neurovascular spheroids (NVUs) are developed, featuring cell‐loaded poly‐3‐hydroxybutyrate 4‐hydroxybutyrate(P34HB) porous microsphere cores embedded within Gelatin Methacryloyl. NVUs formed complex vascular plexuses and secreted extracellular matrix in vitro, simulating autologous nerves and blood interaction.
Junjin Jie, Jingyi Ju, Zhenxing Wang, Jun Chen, Lin‐Ping Wu, Jiaming Sun   +5 more
wiley   +1 more source

Encapsulation of Small Extracellular Vesicles into Selectively Disassemblable Shells of PEGylated Metal‐Phenolic Networks

Advanced Healthcare Materials, EarlyView.
Small extracellular vesicles (sEVs) are encapsulated into protective shells composed of metal‐phenolic networks (MPNs) and secondary poly(ethylene glycol) layers. This surface modification approach enhances the storage stability of sEVs while maintaining their integrity and functionality. The shells can be selectively disassembled under mild conditions.
Chenyu Wang, Ailifeire Fulati, Kenta Kimura, Xianglan Li, Joseph J. Richardson, Mitsuru Naito, Kanjiro Miyata, Takanori Ichiki, Hirotaka Ejima   +8 more
wiley   +1 more source

Protocol to measure the impact of Clostridioides difficile toxins on antibody responses using ELISA, ELISPOT, and toxin-neutralization assays

STAR Protocols
Summary: To determine the effects of bacterial toxins on the humoral immune response, accurate measurement of antibody quantity, specificity, and function is critical. Here, we present a murine injection protocol for bacterial toxins and vaccine antigens
Kaylee M. Norman, Gillian A. Lang, Jimmy D. Ballard, Mark L. Lang   +3 more
doaj  

Gut-derived bacterial toxins impair memory CD4+ T cell mitochondrial function in HIV-1 infection. [PDF]

J Clin Invest, 2022
Ferrari B, Da Silva AC, Liu KH, Saidakova EV, Korolevskaya LB, Shmagel KV, Shive C, Pacheco Sanchez G, Retuerto M, Sharma AA, Ghneim K, Noel-Romas L, Rodriguez B, Ghannoum MA, Hunt PP, Deeks SG, Burgener AD, Jones DP, Dobre MA, Marconi VC, Sekaly RP, Younes SA.   +21 more
europepmc   +1 more source

Mucosal immunization with a bacterial protein antigen genetically coupled to cholera toxin A2/B subunits. [PDF]

, 1995
George Hajishengallis, Susan K. Hollingshead, Toshiya Koga, Michael W. Russell   +3 more
openalex   +1 more source

Fabrication of a Lipopolysaccharide‐Targeting Peptide‐Based Colloid for Alleviating Carbapenem‐Resistant Enterobacteriaceae‐Induced Cutaneous Infection

Advanced Healthcare Materials, EarlyView.
In this study, a novel cationic peptide, IW is designed and synthesized, with a tandem‐repeat sequence demonstrating potent activities against a broad spectrum of clinically relevant Carbapenem‐resistant Enterobacteriaceae in both the planktonic and biofilm states. IW is then formulated with P407 to form IW‐P407 colloids.
Ping Zeng, Xinyi Ding, Chenyu Liu, Sheng Chen, Kin‐Fai Chan, Sharon Shui Yee Leung   +5 more
wiley   +1 more source

Bacterial Toxins Are a Never-Ending Source of Surprises: From Natural Born Killers to Negotiators. [PDF]

Toxins (Basel), 2021
Lopez Chiloeches M, Bergonzini A, Frisan T.   +2 more
europepmc   +1 more source

Bacterial Toxins Block Endothelial Wound Repair [PDF]

, 1997
Martin Aepfelbacher, Markus Essler, Elisabeth Huber, Motoyuki Sugai, Christian Weber   +4 more
openalex   +1 more source