Results 51 to 60 of about 1,432,377 (335)
Mechanism of Gene Regulation by a
The virulence of many bacterial pathogens, including the important human pathogen Staphylococcus aureus, depends on the secretion of frequently large amounts of toxins. Toxin production involves the need for the bacteria to make physiological adjustments
Hwang-Soo Joo+8 more
doaj +1 more source
This 26th edition of the annual Meeting on Toxinology (RT26) of the SFET (http://sfet.asso.fr/international) was held at the Institut Pasteur of Paris on 4−5 December 2019 [...]
Pascale Marchot+3 more
doaj +1 more source
Pneumonia is a leading cause of death in children and the elderly worldwide, accounting for 15% of all deaths of children under 5 years old. Streptococcus pneumoniae is a common and aggressive cause of pneumonia and can also contribute to meningitis and ...
Xueyi Li+14 more
semanticscholar +1 more source
A widespread family of polymorphic toxins encoded by temperate phages
Background Polymorphic toxins (PTs) are multi-domain bacterial exotoxins belonging to distinct families that share common features in terms of domain organization.
Anne Jamet+7 more
doaj +1 more source
Gut-Derived Metabolites and Their Role in Immune Dysfunction in Chronic Kidney Disease
Several of the uremic toxins, which are difficult to remove by dialysis, originate from the gut bacterial metabolism. This opens opportunities for novel targets trying to decrease circulating levels of these toxins and their pathophysiological effects ...
Griet Glorieux+2 more
doaj +1 more source
Toxin-antitoxins and bacterial virulence [PDF]
Bacterial virulence relies on a delicate balance of signals interchanged between the invading microbe and the host. This communication has been extensively perceived as a battle involving harmful molecules produced by the pathogen and host defenses. In this review, we focus on a largely unexplored element of this dialogue, as are toxin-antitoxin (TA ...
Lobato-Márquez, D+2 more
openaire +5 more sources
The Biological Properties of Bacterial Toxins
Knowledge of the biological properties of bacterial toxins is constantly being updated. Over the past two decades, the research interest has shifted from natural toxins to their genetically modified derivatives.
M. V. Supotnitskiy
doaj +1 more source
Functional Consequences of Calcium Influx Promoted by Bacterial Pore-Forming Toxins
Bacterial pore-forming toxins induce a rapid and massive increase in cytosolic Ca2+ concentration due to the formation of pores in the plasma membrane and/or activation of Ca2+-channels.
S. Bouillot, E. Reboud, P. Huber
semanticscholar +1 more source
Metabolic dysfunction‐associated steatotic liver disease (MASLD) affects nearly one‐third of the global population and poses a significant risk of progression to cirrhosis or liver cancer. Here, we discuss the roles of hepatic dendritic cell subtypes in MASLD, highlighting their distinct contributions to disease initiation and progression, and their ...
Camilla Klaimi+3 more
wiley +1 more source