Results 191 to 200 of about 213,855 (329)

Molecular Characterization of Bacterial Virulence Factors and the Consequences for Vaccine Design The 1988 Fleming Lecture [PDF]

, 1989
David Gordon
openalex   +1 more source

Synthetic Cathepsin B Sensitive Adjuvant‐Peptide Conjugates to Target Intracellular Toll‐Like Receptors 7 and 8

ChemistryEurope, EarlyView.
Cathepsin B‐sensitive peptide–adjuvant conjugates are designed, synthesized, and evaluated to deliver an antigenic peptid and an adjuvant targeting Toll‐like receptors 7 and 8 (TLR7/8) to antigen presenting cells. The adjuvant is released by cathepsin B resulting in antigen presentation and TLR mediated T cell activation.
Marjolein M. E. Isendoorn, Giulia Castello, Nico J. Meeuwenoord, Martijn Verdoes, Jeroen D. C. Codée, Ferry Ossendorp, Dmitri V. Filippov   +6 more
wiley   +1 more source

Current challenges and improvements in assessing the immunogenicity of bacterial vaccines. [PDF]

Front Microbiol
Fantoni G, Boccadifuoco G, Verdirosa F, Molesti E, Manenti A, Montomoli E.   +5 more
europepmc   +1 more source

Design of live attenuated bacterial vaccines based on D-glutamate auxotrophy. [PDF]

Nat Commun, 2017
Cabral MP, García P, Beceiro A, Rumbo C, Pérez A, Moscoso M, Bou G.   +6 more
europepmc   +1 more source

Development of aChlamydia trachomatisbacterial ghost vaccine to fight human blindness

, 2008
Francis O. Eko, Talin Barisani‐Asenbauer   +1 more
openalex   +2 more sources

Catalytic Amyloids: Turning Fibrils Into Biocatalysts

Chemistry – A European Journal, EarlyView.
Amyloids, traditionally associated with diseases, have emerged as versatile catalytic scaffolds. From natural amyloid sequences to bioinspired and de novo designs, we highlight strategies to construct catalytic active sites and anchor enzymes onto fibrils, creating versatile nanomaterials with tunable activities. ABSTRACT Amyloids have been regarded as
Alessandra Esposito, Linda Leone, Flavia Nastri, Angela Lombardi   +3 more
wiley   +1 more source

Immunological Insights and Therapeutic Advances in COPD: Exploring Oral Bacterial Vaccines for Immune Modulation and Clinical Improvement. [PDF]

Vaccines (Basel)
Lewicki S, Bałan BJ, Stelmasiak M, Radomska-Leśniewska DM, Szymański Ł, Rios-Turek N, Bień-Kalinowska J, Szarpak Ł, Hajduk B.   +8 more
europepmc   +1 more source

Construction of a full-length infectious bacterial artificial chromosome clone of duck enteritis virus vaccine strain [PDF]

, 2013
Liu Chen, Bin Yu, Jionggang Hua, Weicheng Ye, Zheng Ni, Tao Yun, Xiaohui Deng, Cun Zhang   +7 more
openalex   +1 more source

Porous Organic Frameworks‐Based Nanomaterials in Colorectal Cancer Therapy: From Drug Delivery to Personalized Nano‐Vaccine

Cancer Nexus, EarlyView.
ABSTRACT Colorectal cancer (CRC), as the second most common cause of cancer death worldwide, has seen a significant increase in its incidence rate in recent years. However, the current major clinical treatment methods, such as surgery, chemotherapy and radiotherapy, still have certain limitations and are difficult to achieve a complete cure.
Xiaoyu Song, Hao Zhang, Yinghui Wang, Chao Luo   +3 more
wiley   +1 more source

Mechanisms of Resistance to Cancer Immunotherapy: A Host–Tumor Interaction Perspective; A Review Article

Cancer Nexus, EarlyView.
Mechanisms of resistance to cancer immunotherapy from a host–tumor interaction perspective. The central tumor cell is protected by multiple resistance mechanisms, including genetic mutations, epigenetic modifications, and metabolic alterations. The immunosuppressive tumor microenvironment features myeloid‐derived suppressor cells (MDSCs), regulatory T ...
Mohammed Elmujtba Adam Essa, Hamid Noori, Abdelkareem A. Ahmed   +2 more
wiley   +1 more source