From Dysbiosis to Disease: How Vaginal Microbiota Shape Group B Streptococcus Pathogenesis
Lactobacillus crispatus plays a critical role in the vaginal microbiome. Limiting glucose shifts metabolism toward HMO consumption and amino acid metabolism. These actions enable alkali production and competition. Homeostasis, characterized by dense Lactobacilli colonization and suppression of pathogens, provides resistance to dysbiosis.
Julie A. Talbert, Steven D. Townsend
wiley +1 more source
The Incidence of Co-occurrence of Chlamydial Cervicitis with Bacterial Vaginosis [PDF]
Background and Objectives: Bacterial vaginosis is caused by an imbalance in normal vaginal bacterial flora mainly caused by the introduction of pathogenic bacteria.
Yusefi S +5 more
doaj +2 more sources
ABSTRACT Background and Aims Despite routine prophylactic antibiotics, post‐cesarean infectious morbidity remains a major challenge. Preoperative vaginal preparation can reduce vaginal microbial load, but direct comparisons are scarce. This study compared metronidazole gel versus povidone‐iodine for preventing post‐cesarean infection‑related ...
Fatemeh Davodabadi +4 more
wiley +1 more source
Exploring Cervical Cancer‐Associated Vaginal and Cervical Microbiota via 16S rRNA Sequencing
This 16S sequencing study identified a dysbiotic cervical microbiota (increased diversity, reduced Lactobacillus, enriched Prevotella) specifically linked to high‐risk HPV infection. These microbial alterations, shaped by the HPV‐driven microenvironment, offer novel targets for biomarkers and mechanistic research in cervical carcinogenesis.
Guojiao Wang +5 more
wiley +1 more source
Bacterial vaginosis and probiotics
: Background and aim: Bacterial vaginosis is one of the most common infections of reproductive system ,which results from replacement of the hydrogen peroxide –producing lactobacillus species by various anaerobic bacteria.
amiraliakbari, Sedigheh, Tafazoli, hoda
core +1 more source
Daycare and home dust predominantly harbour commensal and environmental bacteria; however, a significant proportion remains unclassified, indicating routine childhood exposure to novel microorganisms. Both environments contain species with probiotic and immunostimulatory properties that may confer protection against non‐communicable diseases including ...
Jill A. McKay +2 more
wiley +1 more source
Screening for bacterial vaginosis
The IIDSOG-USA has advocated antepartum screening for bacterial vaginosis (BV) in all pregnant women in an attempt to prevent premature delivery. The point is well made that there are a number of screening tests routinely performed during pregnancy that may or may not be beneficial. The question of whether or not routine screening for BV has merit with
openaire +2 more sources
Community-based trial of screening for Chlamydia trachomatis to prevent pelvic inflammatory disease: the POPI (prevention of pelvic infection) trial. [PDF]
BACKGROUND: Pelvic inflammatory disease (PID) is common and can lead to tubal factor infertility, ectopic pregnancy or chronic pelvic pain. Despite major UK government investment in the National Chlamydia Screening Programme, evidence of benefit remains ...
Atherton, H +32 more
core +2 more sources
Genital Tract and Circulating CD8+ T Cell Phenotypes Vary Across the Menstrual Cycle
ABSTRACT Problem The menstrual cycle consists of two main phases: the follicular phase, characterized by rising estradiol and low progesterone, and the luteal phase, marked by elevated progesterone following ovulation. Changes in sex hormones have profound physiological effects, yet their impact on immunity remains poorly understood.
Irene Cruz Talavera +16 more
wiley +1 more source
Comparison between Effectiveness of Lactobacillus Acidophilus Suppository and Metronidazole Vaginal Tablet with Aim of Regulation of Vaginal PH in Patients with Bacterial Vaginosis [PDF]
Background & Objectives: Increase in vaginal pH is an indicator of bacterial vaginosis , changing a healthy acidic environment to a more acidic than 4.5.
محمدپوراصل, اصغر +5 more
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