Results 11 to 20 of about 169,412 (160)
Bacterial hemolysins as virulence factors [PDF]
Antonie van Leeuwenhoek, 1988 No abstract ...
Goebel, Werner +2 more
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Antibiotics, 2023 This narrative review paper provides an up-to-date overview of the potential of novel synthetic and semisynthetic compounds as antibacterials that target virulence traits in resistant strains.
Dejan Stojković +4 more
doaj +1 more source
Phosphorylation of CFP10 modulates Mycobacterium tuberculosis virulence
mBio, 2023 Virulence effectors secreted by Mycobacterium tuberculosis (Mtb) help subvert host immune mechanisms and, therefore, are critical for establishing infection and pathogenesis. However, knowledge in terms of signaling mechanisms that modulate the secretion
Basanti Malakar +9 more
doaj +1 more source
Transposon mutagenesis reveals Pseudomonas cannabina pv. alisalensis optimizes its virulence factors for pathogenicity on different hosts [PDF]
PeerJ, 2019 Pseudomonas cannabina pv. alisalensis (Pcal), which causes bacterial blight disease of Brassicaceae, is an economically important pathogen worldwide. To identify Pcal genes involved in pathogenesis, we conducted a screen for 1,040 individual Pcal KB211 ...
Nanami Sakata +4 more
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Bacterial Sphingomyelinases and Phospholipases as Virulence Factors [PDF]
Microbiology and Molecular Biology Reviews, 2016 SUMMARYBacterial sphingomyelinases and phospholipases are a heterogeneous group of esterases which are usually surface associated or secreted by a wide variety of Gram-positive and Gram-negative bacteria. These enzymes hydrolyze sphingomyelin and glycerophospholipids, respectively, generating products identical to the ones produced by eukaryotic ...
Flores Díaz, Marietta +4 more
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Bacterial phospholipases C with dual activity: phosphatidylcholinesterase and sphingomyelinase
FEBS Open Bio, 2021 Bacterial phospholipases and sphingomyelinases are lipolytic esterases that are structurally and evolutionarily heterogeneous. These enzymes play crucial roles as virulence factors in several human and animal infectious diseases.
Laura Monturiol‐Gross +3 more
doaj +1 more source
Virulence factors impair epithelial junctions during bacterial infection [PDF]
Journal of Clinical Laboratory Analysis, 2020 AbstractEpithelial cells are typically connected through different types of cell junctions that are localized from the apical membrane to the basal surface. In this way, epithelium cells form the first barrier against pathogenic microorganisms and prevent their entry into internal organs and the circulatory system.
Manxi Zheng +3 more
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Citrobacter amalonaticus Inhibits the Growth of Citrobacter rodentium in the Gut Lumen
mBio, 2021 Gut bacterial infections involve three-way interactions between virulence factors, the host immune responses, and the microbiome. While the microbiome erects colonization resistance barriers, pathogens employ virulence factors to overcome them.
Caroline Mullineaux-Sanders +7 more
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When is a bacterial “virulence factor” really virulent? [PDF]
, 2016 ABSTRACTBacterial traits that contribute to disease are termed ‘virulence factors’ and there is much interest in therapeutic approaches that disrupt such traits. However, ecological theory predicts disease severity to be multifactorial and context dependent, which might complicate our efforts to identify the most generally important virulence factors ...
Granato, Elisa T. +3 more
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Sodium Citrate Alleviates Virulence in Pseudomonas aeruginosa
Microorganisms, 2022 The development of bacterial resistance is an insistent global health care issue, especially in light of the dwindled supply of new antimicrobial agents.
Maan T. Khayat +9 more
doaj +1 more source