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VFDB: a reference database for bacterial virulence factors [PDF]
Bacterial pathogens continue to impose a major threat to public health worldwide in the 21st century. Intensified studies on bacterial pathogenesis have greatly expanded our knowledge about the mechanisms of the disease processes at the molecular level over the last decades.
Chen, Lihong +6 more
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Inhibition of bacterial virulence factors as a method of treating bacterial pneumonia
Incremental increase in the number of antibiotic-resistant bacterial strains in the etiologic structure of pneumonia and reduced potential of antibiotic therapy increase the importance of drugs in the treatment of pneumonia, which are aimed at ...
А.Е. Abaturov, Т.А. Kryuchko
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Virulence reduction in Bacteriophage resistant bacteria
Bacteriophages can influence the abundance, diversity and evolution of bacterial communities. Several bacteriophages have been reported to add virulence factors to their host and to increase bacterial virulence.
Marcela eLeón, Roberto eBastías
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Background Pathogenic microorganisms cause disease by invading, colonizing, and damaging their host. Virulence factors including bacterial toxins contribute to pathogenicity. Additionally, antimicrobial resistance genes allow pathogens to evade otherwise
Laura de Nies +7 more
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Helicobacter pylori Virulence Factors Exploiting Gastric Colonization and its Pathogenicity
Helicobacter pylori colonizes the gastric epithelial cells of at least half of the world’s population, and it is the strongest risk factor for developing gastric complications like chronic gastritis, ulcer diseases, and gastric cancer.
Shamshul Ansari, Yoshio Yamaoka
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Type-III effectors: Sophisticated bacterial virulence factors
Bacterial pathogens cause a wide spectrum of diseases in human and other animals. Some virulence factors, which are referred to as effectors, are directly translocated into the host cell via an injection apparatus, i.e., the type-III secretion system.
Akio, Abe +2 more
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Laboratory Plasticware Induces Expression of a Bacterial Virulence Factor
Millions of tons small plastic pieces (microplastic) find their way into the environment every year. They pose digestive and toxicity problems to various life forms in soil, freshwater, and seawater.
Philipp Hansen +3 more
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Periodontitis is an inflammatory condition caused by bacteria and represents a serious health problem worldwide as the inflammation damages the supporting tissues of the teeth and may predispose to systemic diseases.
Helene R. Haugsten +7 more
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Bacteria use a variety of secreted virulence factors to manipulate host cells, thereby causing significant morbidity and mortality. We report a mechanism for the long-distance delivery of multiple bacterial virulence factors, simultaneously and directly ...
Jennifer M Bomberger +5 more
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Electrical Evaluation of Bacterial Virulence Factors Using Nanopores
In this work, we propose a novel methodology for electrical monitoring using nanoporous alumina membranes of virulence factors secreted by bacterial pathogens. Bacterial hyaluronidase (HYAL), which is produced by a number of invasive Gram-positive bacteria, is selected as a model compound to prove the concept.
Escosura Muñiz, Alfredo de la +2 more
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