Results 161 to 170 of about 55,271 (286)

Host–Pathogen Dual Targeting With Repurposed Drugs Identifies a Synergistic Therapy for Intracellular Staphylococcus aureus

MicrobiologyOpen, Volume 15, Issue 3, June 2026.
A large intracellular drug‐repurposing screen identifies a potent synergy between 5‐fluoro‐2′‐deoxycytidine and rifapentine, acting through dual host–pathogen targeting to reduce Staphylococcus aureus burdens across strains, cell types, and infection models (created with BioRender).
Blanca Lorente‐Torres, Helena Á. Ferrero, Pablo Castañera, Jesús Llano‐Verdeja, Sergio Fernández‐Martínez, Amanda Herrero‐González, Farzaneh Javadimarand, Roberto López, Jesús F. Aparicio, Andrew M. Edwards, Volker Behrends, Luis M. Mateos, Álvaro Mourenza, Michal Letek   +13 more
wiley   +1 more source

[Study of the bacteriological quality of water used in the agro-food industry in the North of Morocco]. [PDF]

Pan Afr Med J, 2017
Haijoubi EH, Benyahya F, Bendahou A, Essadqui FZ, Behhari ME, El Mamoune AF, Ghailani NN, Mechita MB, Barakat A.   +8 more
europepmc   +1 more source

Inoculation With Azospirillum brasilense and Bacillus amyloliquefaciens Enhances Tomato Resilience to Severe Water Deficit: A Comprehensive Morpho‐Physiological and Biochemical Analysis

Environmental Microbiology Reports, Volume 18, Issue 3, June 2026.
Inoculation with Azospirillum brasilense and Bacillus amyloliquefaciens significantly enhances tomato tolerance to severe water deficit. This strategy boosts agronomic performance, strengthens antioxidant defences and regulates secondary metabolites, providing a sustainable agricultural approach to combat water scarcity and climate change impacts ...
Camila Garcia de Freitas, Mádilo Lages Vieira Passos, Mariana de Vasconcelos Dias, Leandro Israel da Silva, Lilian Ferreira de Sousa, Filipe Almendagna Rodrigues, Caroline Dambroz, Vytória Piscitelli Cavalcanti, Joyce Dória   +8 more
wiley   +1 more source

Transcriptomic analysis reveals the hepatic response mechanisms of the Chinese spiny frog (Quasipaa spinosa) to Citrobacter freundii infection

Journal of the World Aquaculture Society, Volume 57, Issue 3, June 2026.
Abstract To elucidate the pathogen and host response mechanisms underlying mass mortality in Quasipaa spinosa, dominant bacteria were isolated from diseased individuals and identified as Citrobacter freundii by morphological, physiological, and biochemical characterization, 16S rRNA sequencing, and phylogenetic analysis.
Yanhong Li, Baohong Zhou, Yiran Lu, Yi Zang, Minghao Hu, Qiaochen Jin, Wenbin Fang, Shanjian Zheng   +7 more
wiley   +1 more source

Infectious Diseases Management in Small‐Scale Freshwater Aquaculture in West Africa: Lessons for Low‐ and Middle‐Income Countries

Reviews in Aquaculture, Volume 18, Issue 3, June 2026.
ABSTRACT Infectious diseases are an increasing threat to food security, small‐scale livelihoods and the sustainability of aquaculture in low‐ and middle‐income countries (LMICs). In sub‐Saharan Africa, aquaculture is expanding rapidly but production systems often remain fragile.
Mame Boucar Diouf, Robane Faye, Ahou Rachel Koumi, Nounagnon Darius Tossavi, Enoutchy Fabrice Bouah, Ephigénie Ndew Dione, El Hadji Malick Sy Camara, Kadjo Henri Joel Niamien, Ué Clavier Zéa Bi, Atto Delphin Kouadio, El Hadji Papa Abdourahim Sy, Thérèse Adeline Fatou Gomis, Paul Mamadou Ndour, Konan Jean Baptiste Djanhan, Samba Diouf, Jean‐Christophe Avarre, Jean Fall, Elie Montchowui, Koffi Charles Boussou   +18 more
wiley   +1 more source

Detection of Leptospira in cane toads (Rhinella jimi) from urban and rural Paraíba, Brazil

Veterinary Record, Volume 198, Issue 10, Page e461-e470, 16/23 May 2026.
Abstract Background Leptospirosis is a significant zoonosis in tropical regions, where poor sanitation and favourable climate aid its spread. Synanthropic animals such as the cane toad (Rhinella jimi), which share environments with both people and wild and domestic animals, may harbour Leptospira and contribute to urban and rural transmission cycles ...
Karla N. de Souza Rocha, Aline de Lima Peixoto, Lucila S. de Medeiros Pereira, Debora Ferreira Cardoso, Maria L. C. Rodrigues Silva, Sérgio S. de Azevedo, Juliana P. F. de Oliveira, Clebert J. Alves, Mozar Alves Fonseca, Severino S. dos Santos Higino   +9 more
wiley   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, Volume 600, Issue 9, Page 1373-1385, May 2026.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

Pharmaceutical research in Wilhelmine Germany: The case of E. Merck [PDF]

In this paper, we describe the emergence and evolution of pharmaceutical research at the German company E. Merck during the late 19th and early 20th century.
Carsten Burhop
core  

Bacteriological quality, antimicrobial resistance profile of Escherichia coli, and associated risk factors in tap water, Addis Ababa, Ethiopia. [PDF]

Sci Rep
Kassa DF, Bedada TL, Abera D, Getaneh A, Andaga KD, Tesema TF, Legese MH.   +6 more
europepmc   +1 more source

AAA+ protein unfoldases—the Moirai of the proteome

FEBS Letters, Volume 600, Issue 10, Page 1444-1474, May 2026.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source