Results 171 to 180 of about 434,771 (384)
B‐EPIC: A Transformer‐Based Language Model for Decoding B Cell Immunodominance Patterns
B‐Epic: Achieving high‐accuracy B cell epitope prediction through Transformer architecture. Comprehensive validation demonstrates B‐Epic's robust performance across diverse datasets. B‐Epic facilitates vaccine development for H. pylori and EBV, addressing critical public health challenges.
Jun‐Ze Liang +16 more
wiley +1 more source
The Action of Pasteurella pestis Bacteriophage on Strains of Pasteurella, Salmonella , and Shigella [PDF]
A. S. Lazarus, J. B. Gunnison
openalex +1 more source
The Promising Viral Threat to Bacterial Resistance: The Uncertain Patentability of Phage Therapeutics and the Necessity of Alternative Incentives [PDF]
Bacteriophages, or “phages,” are a category of highly adept and adaptable viruses that can infect and kill bacteria. With concerns over the burgeoning antibiotic-resistance crisis looming in recent years, scientists and policymakers have expressed a ...
Todd, Kelly
core +1 more source
An enhanced one‐pot, helicase‐assisted recombinase polymerase amplification (hRPA)‐combined, dual‐CRISPR/uAsCas12a assay is developed and lyophilized on a 3D‐printed microfluidic disc to achieve field‐deployable multiplex bacteria detection. Abstract One‐pot CRISPR‐based detection combining recombinase polymerase amplification (RPA) enables rapid and ...
Yuqing Shen, Bo Lu, Biao Ma, Xiong Ding
wiley +1 more source
A genome‐scale model guided the systematic metabolic engineering of Saccharopolyspora spinosa, enabling a 5.5‐fold boost in the green bioinsecticide spinosad to 1.8 g L−1 and establishing an actinomycete framework for complex natural products overproduction.
Shuliu Wang +9 more
wiley +1 more source
A Quantitative Study of the Respiration of Staphylococcus Cultures Lysed by Bacteriophage [PDF]
Monroe D. Eaton
openalex +1 more source
CRISPR‐DNA Polymerase Assisted Targeted Mutagenesis for Regulable Laboratory Evolution
This study develops an in vivo targeted mutagenesis system based on CRISPR‐guided bacteriophage T5 or T7 DNA polymerases. This system can enable all possible types of substitution mutations within an expanded mutagenesis window in Escherichia coli and exhibit application potential in different microorganisms, thus accelerating the evolution of ...
Shuaili Chen +8 more
wiley +1 more source
A STUDY OF LYSIS IN BACTERIOPHAGE-INFECTEDESCHERICHIA COLI [PDF]
Arthur Brown
openalex +1 more source
Bacterial wilt disease, the one of the major diseases of potatoes, caused by Ralstonia syzygii subsp. indonesiensis (Rsi). Many efforts have been made to control bacterial wilt disease, including physical control, chemicals, and the use of ...
Nur Azizah, Irda Safni
doaj +3 more sources
A Cas12a@MnO2 nanosponge (hMNS) nanoprobe is engineered to overcome the intracellular delivery and kinetic barrier of the conventional CRISPR/Cas12a system via GSH‐responsive release and Mn2⁺‐enhanced trans‐cleavage. It enables preamplification‐free detection of mRNA with single‐cell sensitivity, differentiation of mRNA expression between breast cancer
Wen‐jing Liu +3 more
wiley +1 more source

