Results 191 to 200 of about 355,018 (412)

A bacteriophage T7 RNA polymerase/promoter system for controlled exclusive expression of specific genes.

open access: yesProceedings of the National Academy of Sciences of the United States of America, 1985
S. Tabor, C. Richardson
semanticscholar   +1 more source

Safety of bacteriophage therapy in severe Staphylococcus aureus infection

open access: yesNature Microbiology, 2020
Aleksandra Petrović Fabijan   +12 more
semanticscholar   +1 more source

Integrating One Health to Mitigate the Emergence and Spread of Antimicrobial Resistance in Livestock and Aquaculture

open access: yesAnimal Research and One Health, EarlyView.
Antimicrobial resistance (AMR) is an escalating global threat driven by antimicrobial use in aquaculture and livestock. Resistant pathogens and genes can spread across humans, animals, and the environment through interconnected ecosystems. Using a One Health approach, this review emphasizes antimicrobial stewardship, regulatory strengthening, enhanced ...
Mir Mohammad Ali   +10 more
wiley   +1 more source

Flow characterization of river to locate bacteriophage isolation sites

open access: yes, 2014
The objective of this book is to validate the experimental work conducted for the characterization of flow by considering environmental aspects. The focus of this book is to characterize flow dynamics of natural river basin to locate potentially diverse ...
Paunikar, Waman   +2 more
core  

Inferring bacteriophage infection strategies from genome sequence: analysis of bacteriophage 7-11 and related phages

open access: yes, 2015
© 2015 Guzina and Djordjevic. Background: Analyzing regulation of bacteriophage gene expression historically lead to establishing major paradigms of molecular biology, and may provide important medical applications in the future.
Guzina, Jelena   +3 more
core   +1 more source

S. aureus colonization and clinical symptoms remain stable upon topical XZ.700 treatment: Results of a double‐blind randomized clinical trial in patients with mild to moderate atopic dermatitis

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aim Recovering dysbiosis may improve atopic dermatitis (AD) symptoms. XZ.700 is a recombinant chimeric endolysin that specifically targets Staphylococcus aureus and could be a new treatment option for patients with AD. The aim of this first‐in‐human study was to evaluate the safety, tolerability and efficacy of topical XZ.700 and explore the ...
Laura W. J. van der Meulen   +13 more
wiley   +1 more source

Engineering Murine Cross‐Reactivity Into an Affibody to Human Death Receptor 5

open access: yesBiotechnology and Bioengineering, EarlyView.
ABSTRACT Interspecies cross‐reactive protein therapeutics that target conserved epitopes across species are critical for translational research. The present study showcases the engineering of an affibody molecule, originally discovered for binding to human death receptor 5 (hDR5) with 94 nM affinity, to simultaneously acquire cross‐reactivity to murine
Tse‐Han Kuo   +3 more
wiley   +1 more source

Engineered B7‐H3 Binding in Modular Gp2 Miniproteins

open access: yesBiotechnology and Bioengineering, EarlyView.
ABSTRACT B7‐H3, an important immune checkpoint modulator of T‐cell function, is a tumor vasculature biomarker and is overexpressed in a variety of cancers. Its expression is associated with tumor growth, metastasis, and poor clinical prognosis, which makes B7‐H3 an appealing target for diagnostics and therapeutics.
Abbigael Harthorn   +5 more
wiley   +1 more source

Home - About - Disclaimer - Privacy