Results 171 to 180 of about 246,265 (316)

Propagation, DNA Extraction Optimization and Genome Sequencing of Bacteriophage [PDF]

This study conducted bacteriophage propagation of three different strains for eight generations on a stable Stenotrophomonas maltophilia host. Infectivity of the bacteriophage was evaluated. Subsequent upscaling, filtration and DNA extraction was carried
Aronee, Atica Amin
core  

Microbiome—pancreatic cancer crosstalk: From tumor biology to therapeutic intervention

iMetaOmics, EarlyView.
The intratumoral microbiome acts as a critical regulator in pancreatic cancer progression and therapeutic resistance. This comprehensive review delineates the origins of pancreatic microbes, elucidates their multifaceted mechanisms in driving immune suppression, metabolic reprogramming, and stromal desmoplasia, and highlights the clinical potential of ...
Yuqin Xie, Jingyuan Ye, Sheng Wang, Maoyun Liu, Fengsheng Dai, Mingzhen Bai, Yi Wang, Athena Savoji, Yu Wang, Phillip B. Hylemon, Huiping Zhou, Hui Li, Dewei Li   +12 more
wiley   +1 more source

Bacteriophage-derived endolysins restore antibiotic susceptibility in β-lactam- and macrolide-resistant Streptococcus pneumoniae infections [PDF]

Streptococcus pneumoniae, the pneumococcus, is a cause of major illness globally. Invasive pneumococcal disease (IPD) is characterized by pneumococci invading blood (bacteremia), lungs (pneumonia), or brain and cerebrospinal fluid (meningitis ...
Niels Vander Elst (18652594), Lisa Knörr (21248527), Kristine Farmen (21248524), Federico Iovino (421388), Lotte Merlijn (21248530)   +4 more
core  

Microbiome and aging: Trajectories of microbiome age across human ecosystems and their systemic effects

iMeta, EarlyView.
Microbiome age (MA) has emerged as an innovative biomarker of biological aging, reflecting host aging trajectories through dynamic alterations in microbial composition, function, and host–microbe interactions across multiple body ecosystems. Diverse computational strategies—including traditional machine learning, deep learning, and multi‐omics ...
Zhexin Ni, Jiaojiao Xie, Zhichun Zhang, Keming Zhang, Jie Ding, Mingyang Chang, Ying Su, Yunan Zhang, Mingfei Yao, Chengyuan Wang, Yan Yan, Wenjie Fang, Hainv Gao, Xuecong Tian, Yangshuo Li, Xinlin Zhu, Wen Zhang, Wanqing Liao, Gaoyuan Xu, Guojing Chen, Xiaoyi Lv, Chaoqin Yu, Weihua Pan, Vadim Molodtsov, Lanjuan Li, Yue Gao, Wei Zhou   +26 more
wiley   +1 more source

Harnessing cracks in metal films: Design strategies for stretchable conductors

InfoMat, EarlyView.
In stretchable electronics, metal film‐based components function either as strain‐insensitive interconnects/electrodes or as strain‐sensitive sensors, both of which are governed by crack‐induced electromechanical responses, yet these two roles have often been discussed separately in previous reviews.
Ting Zhu, Kai Wu, Gang Liu, Jun Sun
wiley   +1 more source

Bacteriophage encapsulation for gastrointestinal tract delivery [PDF]

, 2017
Neve, Horst, Atamer, Z., Hinrichs, J., Franz, Charles M. A. P., Wagner, Natalia, Samtlebe, M.   +5 more
core  

Genomic and functional characterization of a novel halophilic bacteriophage targeting carbapenem-resistant Klebsiella pneumoniae. [PDF]

PLoS One
Abed S, Beig M, Soltani S, Pahlevani M, Speck P, Shafiei M, Shahraki AH, Ghorbani A.   +7 more
europepmc   +1 more source

Enhanced CRISPR‐cas systems for genome editing and molecular diagnostics

Interdisciplinary Medicine, EarlyView.
This review systematically summarizes the major optimization strategies for CRISPR‐Cas systems, focusing on the engineering of Cas proteins, guide RNAs, reporter probes, and the incorporation of chemical additives. The aim is to enhance editing precision and diagnostic capability, thereby expanding the CRISPR system's potential for broader biomedical ...
Sheng Li, Han Li, Bojie Chen, Ling Jiang, Keyu Long, Jiaqi Lang, Xingxiang Pu, Erhu Xiong   +7 more
wiley   +1 more source

Engineering a T7 bacteriophage to attenuate LPS-driven inflammatory responses during bacteriolysis. [PDF]

Appl Environ Microbiol
Yu T, Pang J, Chen M, Sun Q, Pu J, Wang D, Liu Q, Yang F, Deng H.   +8 more
europepmc   +1 more source

Revisiting Burn Wound Infections: A Comprehensive Review on the Dual Potential of Phages and Probiotics Against Acinetobacter baumannii

Journal of Clinical Laboratory Analysis, EarlyView.
Effect Probiotics on immune system modulation and wound Healing. ABSTRACT Introduction Burn wound infections caused by Acinetobacter baumannii remain a critical clinical challenge due to its extensive multidrug resistance, particularly against carbapenems.
Zeinab Fagheei Aghmiyuni, Shahrzad Aliniay Sharafshadehi, Roghayeh Afifirad, Elnaz Bafandeh, Maryam Mokhtaryan, Roya Ghanavati, Atieh Darbandi   +6 more
wiley   +1 more source