Results 271 to 280 of about 373,043 (334)

Novel Wide‐Spectrum Virucidal Lipid Nanoparticles

open access: yesSmall, EarlyView.
POSTAN is a novel broad‐spectrum antiviral nanoparticle that combines safety with potent virucidal activity. Composed of biocompatible lipids, it mimics heparan sulfate proteoglycans and lipid rafts exploited by viruses, thereby dismantling viral envelopes and blocking replication.
Yugo Araújo Martins   +10 more
wiley   +1 more source

Plant‐Derived Viral Nanoparticles Enable Simultaneous Guidance of Neuronal Cell Outgrowth and Targeting of Neurodifferentiation Pathways

open access: yesSmall, EarlyView.
A neuronal tissue engineering approach employing plant‐derived viral nanoparticles (VNPs) that have been genetically engineered to display functional peptides is presented. These VNPs simultaneously promote neuronal differentiation and directional growth.
Mira Ritter   +9 more
wiley   +1 more source

Understanding of endo/lysosomal escape of nanomaterials in biomedical application

open access: yesSmart Molecules, EarlyView.
This review summarized mainstream mechanisms of endo/lysosomal escape and design strategies of endo/lysosomal escapable nanoparticles in view of surface charge, polarity & hydrophobicity, particle morphology, and lysosomal escape agents. The utilization of endo/lysosomal escapable nanoparticles for vaccine delivery and genetic engineering are ...
Xin Wang   +3 more
wiley   +1 more source

Exosome‐Based Cartilage‐Targeted Delivery System: Strategies and Applications

open access: yesSmall Science, EarlyView.
Construction strategies and applications of cartilage‐targeting exosomes. With the ageing of the global population, cartilage‐related diseases, such as osteoarthritis (OA) and intervertebral disc degeneration (IVDD), have increasingly become significant social problems threatening human health. Therefore, targeted therapy for cartilage is becoming more
Yao Wang   +3 more
wiley   +1 more source

Beware of host immune responses towards bacteriophages potentially impacting phage therapy. [PDF]

open access: yesVet Res
Démoulins T   +5 more
europepmc   +1 more source

A Facile Platform for One‐Step Generation of Uniform Microdroplets through Dehydration‐Driven Phase Separation in Microfluidics

open access: yesSmall Methods, EarlyView.
This study introduces a novel droplet generation method that exploits the intrinsic water absorption of polydimethylsiloxane (PDMS) microchannels. A homogeneous polyethylene glycol/dextran mixture is gradually dehydrated, leading to phase separation and the formation of uniform DEX‐rich droplets.
Ken Hirano   +3 more
wiley   +1 more source

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