Results 131 to 140 of about 15,223 (299)

Living Microbial Drugs

Chemistry – A European Journal, EarlyView.
The introduction outlines the review scope. Microbial cell factories as living drugs cover host–gut microbiota, bacteria, yeast, and other microbial systems, with comparative host advantages. Engineering strategies include synthetic circuits, quorum sensing, and memory.
Cemile Elif Özçelik, Nazlıcan Tunç, Senem Şen, Urartu Özgür Şafak Şeker   +3 more
wiley   +1 more source

Cholera Bacteriophages: History of Discovery, Structure and Application

Проблемы особо опасных инфекций
Viruses that affect cholera vibrio, or cholera bacteriophages, were discovered in early twentieth century, when the sixth cholera pandemic was raging in Southeast Asia, the Far and Middle East and Europe.
N. B. Cheldyshova, S. P. Zadnova, E. G. Abramova, A. K. Nikiforov, Z. L. Devdariani   +4 more
doaj   +1 more source

A comparison of three molecular typing methods for the discrimination of Salmonella enterica serovar Infantis

, 2008
Seventy-six epidemiologically unrelated Salmonella enterica serovar Infantis (S. Infantis) isolates were typed by pulsed-field gel electrophoresis (PFGE), multiple amplification of phage loci typing (MAPLT) and multiple-locus variable-number tandem ...
Heuzenroeder, M., Ross, I.
core   +1 more source

De Novo Design of Multivalent α/β‐Peptides Mimicking Transcription Factors Targeting the CBP KIX Domain

Chemistry – A European Journal, EarlyView.
A modular, de novo α/β‐peptide design strategy allows fine‐tuning of ligand properties, resulting in multivalent ligands that simultaneously target separate binding sites on the protein surface. ABSTRACT Protein‐protein interactions that regulate gene expression in the nucleus are increasingly recognized as potential therapeutic targets but present ...
Márk V. Tresztián, Vencel L. Petrovicz, Edit Wéber, Tamás A. Martinek, Zsófia Hegedüs   +4 more
wiley   +1 more source

Antibacterial Hydrogel Dressing With Ca2+‐Dependent Hyaluronidase Responsiveness for Accelerating Wound Healing via On‐Demand Release of AIE Photosensitizers

Exploration, EarlyView.
This study innovates a Ca2+‐responsive hydrogel dressing that releases AIE photosensitizers on‐demand. Low Ca2+ enhances bacterial hyaluronidase (HAase) activity, degrading hyaluronic acid dressing to trigger antibacterial ROS release, while high Ca2+ inhibits HAase, preventing overdosing.
Rongwei Cui, Hao Yang, Miaomiao Kang, Zhijun Zhang, Weilin Xu, Yang Jiang, Lizhou Xu, Xiao‐Yong Zhan, Luhan Zhang, Yunsheng Xu, Dong Wang, Ben Zhong Tang, Danyang Li   +12 more
wiley   +1 more source

Bacteriophage strain typing by rapid single molecule analysis.

, 2015
Rapid characterization of unknown biological samples is under the focus of many current studies. Here we report a method for screening of biological samples by optical mapping of their DNA.
Weinhold, E., Dahan, Moran,, Nilsson, A.,, Weinhold, Elmar,, Ebenstein, Y., Grunwald, A.,, Ebenstein, Yuval, Giesbertz, Anna, Nilsson, Adam, Weinhold, Elmar, Weinhold, E.,, Nyberg, Lena, Westerlund, Fredrik, Giesbertz, A., Ebenstein, Y.,, Ebenstein, Yuval,, Nilsson, Adam,, Ambjornsson, T., Nyberg, Lena K, Dahan, M.,, Dahan, Moran, Nyberg, Lena,, Grunwald, Assaf, Ambjörnsson, Tobias,, Giesbertz, A.,, Giesbertz, Anna,, Grunwald, Assaf,, Grunwald, A., Nyberg, Lena K,, Ambjornsson, T.,, Lund University., Dahan, M., Nilsson, A., Westerlund, Fredrik,, Ambjörnsson, Tobias   +34 more
core   +1 more source

Engineering Bacteria for Medicine: Delivery, Diagnosis, and Therapy

iMetaMed, EarlyView.
ABSTRACT With rapid advances in synthetic biology and genetic engineering, genetically engineered bacteria (GEB) have emerged as a promising platform for biological therapy, addressing key limitations of conventional drug delivery systems and demonstrating significant clinical potential.
Shiyu Xia, Guiling Fu, Xiaoyue Ding, Wen Yang, Ruijie Bai, Yawei Cai, Jing xuan Zhang, Yanxia Wei, Conghui Han, Yi‐Zhou Gao, Ying Li, Zuobin Zhu   +11 more
wiley   +1 more source

Bacteriophage typing of Saprophytic Mycobacteria

Nippon Saikingaku Zasshi, 1961
TOKUNAGA, Tohru, SEKI, Matazo, MARUYAMA, Yoneo, MUROHASHI, Toyoho   +3 more
openaire   +3 more sources

Integrative host–microbiome modeling uncovers the implication of oral–gut translocation in advanced cirrhosis

iMeta, EarlyView.
Liver cirrhosis is associated with profound disruption of host–microbiome metabolic interactions. Using paired oral and fecal metagenomics combined with genome‐scale metabolic modeling, we investigated how microbial translocation along the oral–gut axis influences microbial metabolism at different cirrhosis severities.
Yi Jin, Frederick Clasen, Fernando Garcia‐Guevara, Sania Arif, Robert Schierwagen, Gholamreza Bidkhori, Michael Praktiknjo, Maximilian J. Brol, Frank E. Uschner, Florence A. Castelli, Nicolas Pons, Benoit Quinquis, Nathalie Galleron, Kevin Da Silva, Christophe Junot, Debbie L. Shawcross, David L. Moyes, Rajiv Jalan, S. Dusko Ehrlich, Vishal C. Patel, Jonel Trebicka, Saeed Shoaie   +21 more
wiley   +1 more source

The forgotten typers: The rise and fall of Weimar bacteriophage-typing (1921–1935)

, 2019
International audienceUsing bacteriophages to type (identify) bacteria was one of the most important tools of twentieth-century epidemiology. Challenging existing accounts’ focus on Anglophone research, this paper shows that modern phage-typing arose in ...
Kirchhelle, Claas, Kirchhelle, C
core   +1 more source