Results 131 to 140 of about 14,881 (257)

The gut microbiome and drug‐resistant epilepsy: Microbiome–antiseizure medication interactions and implications for pharmacoresistance

Epilepsia Open, EarlyView.
Abstract Drug‐resistant epilepsy (DRE) affects approximately one‐third of patients with epilepsy and represents a major unmet clinical need. While traditional hypotheses of pharmacoresistance have focused on alterations in drug targets, efflux transporter overexpression, and intrinsic disease severity, the gut microbiome has recently emerged as a ...
Khaled Zammar, Majd A. AbuAlrob, Musab Ali, Simona Lattanzi, Boulenouar Mesraoua   +4 more
wiley   +1 more source

The Forgotten History of Bacteriophages in Bulgaria: An Overview and Molecular Perspective on Their Role in Addressing Antibiotic Resistance and Therapy. [PDF]

Viruses
Kalvatchev N, Khanbabapour T, Sakkeer A, Tsekov I, Delchev Y, Strateva T.   +5 more
europepmc   +1 more source

Antibacterial Hydrogel Dressing With Ca2+‐Dependent Hyaluronidase Responsiveness for Accelerating Wound Healing via On‐Demand Release of AIE Photosensitizers

Exploration, EarlyView.
This study innovates a Ca2+‐responsive hydrogel dressing that releases AIE photosensitizers on‐demand. Low Ca2+ enhances bacterial hyaluronidase (HAase) activity, degrading hyaluronic acid dressing to trigger antibacterial ROS release, while high Ca2+ inhibits HAase, preventing overdosing.
Rongwei Cui, Hao Yang, Miaomiao Kang, Zhijun Zhang, Weilin Xu, Yang Jiang, Lizhou Xu, Xiao‐Yong Zhan, Luhan Zhang, Yunsheng Xu, Dong Wang, Ben Zhong Tang, Danyang Li   +12 more
wiley   +1 more source

OBSERVATIONS ON BACTERIOPHAGE TYPING OF PSEUDOMONAS AERUGINOSA [PDF]

Journal of Clinical Investigation, 1961
B, POSTIC, M, FINLAND
openaire   +2 more sources

Engineering Bacteria for Medicine: Delivery, Diagnosis, and Therapy

iMetaMed, EarlyView.
ABSTRACT With rapid advances in synthetic biology and genetic engineering, genetically engineered bacteria (GEB) have emerged as a promising platform for biological therapy, addressing key limitations of conventional drug delivery systems and demonstrating significant clinical potential.
Shiyu Xia, Guiling Fu, Xiaoyue Ding, Wen Yang, Ruijie Bai, Yawei Cai, Jing xuan Zhang, Yanxia Wei, Conghui Han, Yi‐Zhou Gao, Ying Li, Zuobin Zhu   +11 more
wiley   +1 more source

Performance of FTIR-Based IR Biotyper for Identification and Strain Discrimination of <i>Cryptococcus</i> Species. [PDF]

Mycobiology
Won EJ, Jeon Y, Kim TY, Bahn YS, Sung H, Kim MN.   +5 more
europepmc   +1 more source

Microbiome‐mediated plant‐soil feedbacks as a tool for resilient agriculture

iMetaOmics, EarlyView.
Translating plant‐soil feedbacks (PSFs) into reliable agricultural management requires shifting from input‐dependent practices toward endogenous, process‐driven crop resilience. To bridge this gap, we propose a predictive framework centered on three strategic interventions: engineering the crop holobiont, diversifying the soil habitat, and deploying ...
Muhammad Asif, Hazrat Bilal, Min Xiao, Lei Dong, Wen‐Jun Li   +4 more
wiley   +1 more source

An Overview of the Genetic Diversity and Epidemiological Potential of <i>Yersinia pestis</i> Populations in Natural Plague Foci of Kazakhstan. [PDF]

Pathogens
Abdirassilova A, Yessimseit D, Kassenova A, Rysbekova A, Abdeliyev B, Zhumadilova Z, Abdel Z, Mussagaliyeva R, Meka-Mechenko T, Sairambekova G, Begimbayeva E, Nurpeisova A, Sagidulin T, Maksatova A, Agzam S, Nissanova R, Motin V, Reva O.   +17 more
europepmc   +1 more source

Strategies and mechanisms of precision genome engineering: From gene editing to genome writing

iMetaOmics, EarlyView.
In this review, we examined the progression of genome manipulation from stochastic nuclease‐mediated cutting toward precise editing and programmable genome writing. We discussed tools like multi‐kilobase RNA‐guided integrators and Artificial Intelligence (AI)‐designed effectors and showed how these advances enable researchers to treat genomes as ...
Kerui Huang, Jianhong Tian, Wenyan Zhao, Siqin Zhang, Lixuan Xiang, Meiqing Yang, Lu Liu, Yazhou Huang, Ningyun Zhang, Lei Sun, Peng Xie, Nanyu Kuang, Hong Zhou, Chengfeng Qiu, Jun Yan, Xiaocheng Jiang, Qiang Tu, Yun Wang, Haoliang Hu, Youming Zhang   +19 more
wiley   +1 more source

Complete genome sequences of the lytic bacteriophage PBM-3 and the avian pathogenic <i>Escherichia coli</i> strain PE144. [PDF]

Microbiol Resour Announc
Cherbuin JD, Zhang J, Khan M, Niaz H, Adnan F.   +4 more
europepmc   +1 more source