Advancing Therapies for Mycobacterial Diseases: From Small Molecules to Host‐Directed Strategies
ABSTRACT The global burden of multidrug‐resistant tuberculosis (MDR‐TB) and the rising incidence of nontuberculous mycobacterial (NTM) infections highlight the urgent need for innovative therapeutic strategies. Current treatments are prolonged, toxic, and increasingly compromised by resistance and limited diagnostic capacity.
Tânia Silva +23 more
wiley +1 more source
Genomic Characterization of Antimicrobial Resistance and Virulence in ST11 Carbapenem-Resistant <i>Klebsiella Pneumoniae</i> Colonizing the Intestinal Tract of Elderly Inpatients. [PDF]
Chen J, Liu L, Zhang Y, Ling D, Wang F.
europepmc +1 more source
Diverse Uses of Lantibiotics: Exploring New Approaches to Combat Antibiotic Resistance
This review illustrates lantibiotics as an alternative therapeutic approach to combat antibiotic resistance, highlighting their diverse sources, including plants, insects, animals, and microorganisms. It further emphasizes their broad therapeutic potential, including antibacterial, antifungal, antiparasitic, antiviral, and anticancer activities (GA ...
Gopalarethinam Janani +5 more
wiley +1 more source
Recurrent Urinary Tract Infection Caused by Multidrug-Resistant <i>Klebsiella pneumoniae</i>: A Case Report. [PDF]
Monteiro ASS +4 more
europepmc +1 more source
Biosurfactant was produced by Pseudomonas aeruginosa using andiroba waste from Amazonia. A biosurfactant–alginate composite (Alg/BioS) was successfully synthesized via ionotropic gelation, and achieved up to 70% Cr6+ removal from water. Abstract Environmental contamination by heavy metals represents a significant challenge due to their persistence in ...
Paulo Diniz Austriaco +11 more
wiley +1 more source
Genomic epidemiology and antimicrobial resistance of non-typhoidal Salmonella from retail meats in Beijing, China: implications for foodborne transmission and phage susceptibility. [PDF]
Chen A +12 more
europepmc +1 more source
ABSTRACT Cold atmospheric plasma (CAP) is effective against a variety of microorganisms. Here, we described effects on an Escherichia coli strain isolated from hospital wastewater caused by treatment with physical plasma. E. coli GW‐AmxH19 was incubated in artificial wastewater and treated for 15 min with CAP.
Jörg Bernhardt +11 more
wiley +1 more source
Genetic Characteristics and Preservative Tolerance of Spoilage Microorganisms in Daily Chemical Products. [PDF]
Wen X +8 more
europepmc +1 more source
ABSTRACT Predicted protein structures now enable fold discovery beyond the reach of sequence homology, but scalable and interpretable methods remain limited. We present Cooper‐Beta, a resource‐efficient, chain‐resolved framework for detecting β‐barrel‐like folds from strand connectivity.
Shuyu Zhong, Yuying Jiang
wiley +1 more source

