This study develops a cartilage‐targeted DNA origami system (OCS) that protects and delivers si‐Stat3 to chondrocytes. OCS reduces MMP13 expression, enhances extracellular matrix stability, and lowers oxidative stress while improving cell survival. In vivo, OCS decreases cartilage degradation biomarkers and promotes tissue repair factors, demonstrating
Qi Lv+8 more
wiley +1 more source
Physiological Aspects of Genetics [PDF]
A considerable amount of evidence indicates that desoxyribonucleic acid is capable of duplicating itself, a property also possessed by genes. (By a self-duplicating material, we mean one which plays some essential role in its own production.) Watson ...
Horowitz, N. H., Owen, Ray D.
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Bacteriophage Typing of Listeria monocytogenes Cultures Isolated From Seafoods.
Listeria monocytogenes cultures isolated from a variety of seafoods were subjected to phage typing procedures utilizing the French International set of L. monocytogenes bacteriophages.
L. A. Estela, J. Sofos, Barbara Flores
semanticscholar +1 more source
Bacteriophage Types and Antibiotic Sensitivity of Staphylococci from Bovine Milk and Human Nares [PDF]
Robert H. Jones, F.W. Bennett
openalex +2 more sources
Phenotype-genotype relationships of Escherichia coli O157 and O26 isolates from New Zealand : a thesis presented in partial fulfilment of the requirements for the degree of Master of Science in Microbiology at Massey University, Manawatū, New Zealand [PDF]
Shiga toxin-producing Escherichia coli (STEC) is a zoonotic pathogen responsible for causing severe manifestations of gastroenteritis in humans worldwide.
George, Tessy Thankachen
core
Phages Preying on Bacillus anthracis, Bacillus cereus, and Bacillus thuringiensis: Past, Present and Future [PDF]
Many bacteriophages (phages) have been widely studied due to their major role in virulence evolution of bacterial pathogens. However, less attention has been paid to phages preying on bacteria from the Bacillus cereus group and their contribution to the ...
Ackermann+108 more
core +1 more source
The bacterial Type VI secretion system (T6SS) emerges as a sophisticated virulence mechanism, leveraging the dual‐function effector TkeA from Yersinia pseudotuberculosis. TkeA concurrently damages rival bacteria and host cell DNA, triggering the host's cGAS‐STING‐TNF pathway and inducing apoptosis.
Li Song+13 more
wiley +1 more source
Phenotypic and Genetic Predictors of Pathogenicity and Virulence in Flavobacterium psychrophilum
Flavobacterium psychrophilum causes bacterial cold-water disease (BCWD) in farmed rainbow trout (Oncorhynchus mykiss), with the multilocus sequence typing (MLST) clonal complex (CC) CC-ST10 accounting for the majority of outbreaks globally.
Krister Sundell+9 more
doaj +1 more source
Application of bacteriophages for detection and control of foodborne pathogens [PDF]
The incidence of foodborne infectious diseases is stable or has even increased in many countries. Consequently, our awareness regarding hygiene measures in food production has also increased dramatically over the last decades.
Hagens, Steven, Loessner, Martin
core
Mobile genetic elements in Clostridium difficile and their role in genome function. [PDF]
Approximately 11% the Clostridium difficile genome is made up of mobile genetic elements which have a profound effect on the biology of the organism. This includes transfer of antibiotic resistance and other factors that allow the organism to survive ...
Allan, E, Mullany, P, Roberts, AP
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