Helical reconstruction of amyloids in cryoSPARC
We present practical guidelines for helical reconstruction of amyloid filaments in cryoSPARC, benchmarked against publicly available datasets. Our analysis defines current capabilities and limitations, and outlines optimization strategies to enable high‐throughput structural studies and therapeutic discovery.Amyloid‐mediated proteotoxicity underlies ...
Jan-Hannes Schaefer +5 more
wiley +1 more source
An Overview of the Genetic Diversity and Epidemiological Potential of <i>Yersinia pestis</i> Populations in Natural Plague Foci of Kazakhstan. [PDF]
Abdirassilova A +17 more
europepmc +1 more source
Hotter, faster, sicker? Warming shifts the cost of infection from individuals to populations
This study examines how temperature alters disease impacts across biological scales in a host–pathogen system. We found infected hosts appear healthiest at warm temperatures, yet populations suffer most. This suggests climate warming may intensify disease impacts for populations in ways traditional individual‐level virulence metrics fail to predict ...
Nathan J. Butterworth +2 more
wiley +1 more source
ABSTRACT The aim of this study was to synthesize evidence on the influence of Enterococcus faecalis on endodontic treatment failure and strategies for its elimination. This study followed the Preferred Reporting Items for Systematic Reviews and Meta‐Analyses (PRISMA) guidelines and was registered in PROSPERO (CRD420251022741).
Francine Santos Fernandes de Lima +1 more
wiley +1 more source
Performance of FTIR-Based IR Biotyper for Identification and Strain Discrimination of <i>Cryptococcus</i> Species. [PDF]
Won EJ +5 more
europepmc +1 more source
Another Serologic Type of Streptococcic Bacteriophage [PDF]
A C, Evans, E M, Sockrider
openaire +2 more sources
Complete genome sequences of the lytic bacteriophage PBM-3 and the avian pathogenic <i>Escherichia coli</i> strain PE144. [PDF]
Cherbuin JD +4 more
europepmc +1 more source
Staphylococcus aureus, commonly colonising CTCL patients, augments skin barrier dysfunction. Staphylococcal enterotoxins induce T‐cell release of barrier‐repressing cytokines (IL‐4, IL‐13, IL‐22, OSM). Cytokine signalling drives JAK‐dependent downregulation of filaggrin and loricrin in keratinocytes. Antibiotic‐mediated eradication of S. aureus induces
Maria Gluud +23 more
wiley +1 more source
Anthropogenic Disruption Versus Natural Restoration: Enterobacter cloacae-Driven Barnacle Larval Settlement and Its Mitigation via Natural Bacteriophages. [PDF]
Khan A, Saha A, Joshi HM.
europepmc +1 more source
ABSTRACT Allergic diseases arise from aberrant immune recognition of otherwise harmless environmental proteins and are driven by epitope‐specific interactions between allergens and the adaptive immune system. Although component‐resolved diagnostics have improved molecular characterisation of sensitization, they remain limited to whole‐allergen ...
Mark Møiniche +11 more
wiley +1 more source

