Results 171 to 180 of about 14,881 (257)

Responsive nitric oxide‐releasing antibacterial materials for biofilm‐associated infections: Mechanisms, design strategies, and applications

open access: yesResponsive Materials, EarlyView.
This review summarizes the recent progress in responsive NO‐releasing materials and their applications in biofilm‐associated infectious diseases. The design principles and response mechanisms are given to provide inspiration toward the future development of multi‐responsive NO‐releasing materials.
Wenyue Sun   +8 more
wiley   +1 more source

Discriminating Between Living and Dead Bacteria With a Field‐Effect Transistor Based on Nano‐Channels

open access: yesSmall, EarlyView.
Bacterial viability is determined in a complex environment with a field‐effect biological transistor with a limit of detection of a single bacterium. Living, antibiotic‐treated, thermally denatured, and inhibited E. coli generate distinct electrical signatures, enabling label‐free single‐cell detection and providing new opportunities for rapid ...
Bar Chen   +17 more
wiley   +1 more source

Targeting the CD47–SIRPα phagocytic checkpoint in cancer: Biology, translational opportunities, and next‐generation therapeutic strategies

open access: yesSmart Molecules, EarlyView.
The CD47–SIRPα axis has emerged as a critical innate immune checkpoint that suppresses macrophage‐mediated phagocytosis through a canonical “don't eat me” signal and enables tumor immune evasion. We comprehensively summarize the structural and biological features of CD47 and the molecular mechanisms underlying CD47‐mediated regulation of phagocytosis ...
Ruimei Zhou   +4 more
wiley   +1 more source

DOM: Dual Optical Mapping Integrating Sequence‐Specific Barcodes and A/T Density Profiles

open access: yesSmall Methods, EarlyView.
Dual Optical Mapping (DOM) combines sequence‐specific barcodes and an A/T profile to generate complementary genomic signatures along single DNA molecules. The integration of sparse and dense mapping information enables accurate and confident genome mapping, facilitating reliable localization of long DNA molecules in complex genomes, including the ...
Jaeyoung Bae   +10 more
wiley   +1 more source

Bee sting-induced hypervirulent <i>Klebsiella pneumoniae</i> infection causing fulminant necrotizing fasciitis: case report and narrative review. [PDF]

open access: yesNew Microbes New Infect
Hu Y   +12 more
europepmc   +1 more source

Peptide‐directed nanovehicles enabling tumor‐selective ROS amplification and antitumor immunity

open access: yesVIEW, EarlyView.
Cancer cells are vulnerable to oxidative stress, yet exploit immune tolerance to escape destruction. In contrast, their metabolic profile is markedly altered to support rapid proliferation, accompanied by elevated production of reactive oxygen species (ROS).
Manuela Calin   +3 more
wiley   +1 more source

Rapid Typing of Extended-Spectrum β-Lactamase (ESBL)- and Metallo-β-Lactamase (MBL)-Producing Enterobacterales Using Fourier Transform Infrared (FT-IR) Spectroscopy. [PDF]

open access: yesMicrobiologyopen
Kawamoto Y   +9 more
europepmc   +1 more source

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