Results 251 to 260 of about 25,843 (353)

AllergoOncology in Review: Harnessing Allergy in the Field of Oncology to Improve Patient Outcomes

open access: yesClinical &Experimental Allergy, EarlyView.
ABSTRACT The AllergoOncology field brings together the study of allergic and cancer immune responses, having evolved from early epidemiological studies that reported inverse associations between allergies, IgE and cancer risk. Insights from studying allergic inflammation are revealing previously unappreciated immune mechanisms that confer protective ...
Jakub Zydron   +13 more
wiley   +1 more source

Phosphatase PPP1CC Regulates the First Lineage Segregation by GAS5 in Mouse Preimplantation Embryos

open access: yesCell Proliferation, EarlyView.
Subcortical GAS5 directs PPP1CC phosphatase spatiotemporal positioning during mouse morula‐blastocyst transition, controlling YAP dephosphorylation to drive first embryonic lineage specification. ABSTRACT The transcriptional effector of the Hippo signalling pathway, YAP, regulates the first lineage specification in mouse preimplantation embryos ...
Jianwu Wang   +10 more
wiley   +1 more source

Use of IR Biotyper as a feasible methodology to type <i>Klebsiella pneumoniae</i>. [PDF]

open access: yesMicrobiol Spectr
Orlandi Barth P   +5 more
europepmc   +1 more source

Cost of parasite exposure depends on host ontogeny 寄生接觸的代價依賴於宿主發育階段

open access: yesEcological Entomology, EarlyView.
The cost of parasite exposure varies across host developmental stages, demonstrating that ontogeny influences the expression of non‐consumptive effects (NCEs). Mite exposure resulted in consumptive effects in fly eggs and NCEs in early‐stage pupae; mite longevity was comparable when provisioned with pupae or water but increased when provisioned with ...
Lisa R. MacLeod   +2 more
wiley   +1 more source

A widespread bacteriophage abortive infection system functions through a Type IV toxin–antitoxin mechanism

open access: gold, 2014
Ron L. Dy   +4 more
openalex   +1 more source

Investigating the molecular mechanisms underlying the anti‐CRISPR function of AcrIIA13b protein

open access: yesThe FEBS Journal, EarlyView.
Anti‐CRISPR protein AcrIIA13b inhibits CRISPR–Cas9 function by preventing target DNA engagement. The Cas9–sgRNA ribonucleoprotein (RNP) normally recognizes the protospacer adjacent motif (PAM) duplex to initiate DNA cleavage. AcrIIA13b binding to the PAM‐interacting WED–PI domain blocks this recognition, leaving the target DNA intact.
So Yeon Lee, Hyun Ho Park
wiley   +1 more source

Plant‐produced encapsulin displays non‐typhoidal Salmonella enterica antigens and assembles into mosaic nanoparticles

open access: yesThe FEBS Journal, EarlyView.
This study investigates the potential of encapsulin as an antigen display platform for the development of a candidate Salmonella vaccine for poultry. Encapsulin constructs were transiently expressed in Nicotiana benthamiana where they accumulated to high levels.
Carly A. Charron   +6 more
wiley   +1 more source

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