Results 261 to 270 of about 25,843 (353)
Draft genome sequences of New Delhi metallo-beta-lactamase-producing <i>Klebsiella pneumoniae</i> strains isolated from water and wastewater sources. [PDF]
Samadi ZF +10 more
europepmc +1 more source
Quinolones are valuable scaffolds for drug discovery but are rare in nature. Here, we show that two fungal enzymes, AthePKS and FerePKS, can generate 2‐quinolones and two additional heteroaromatic scaffolds. Using AthePKS, we designed an artificial enzymatic cascade towards an antimicrobial quinolone from a simple precursor and implemented it in E ...
Nika Sokolova +5 more
wiley +1 more source
Determination of Genome Size of Selected Typing Bacteriophages of Staphylococcus aureus
Michael W. Pariza, J J Iandolo
openalex +1 more source
Identification of colorectal cancer using enteroviral and bacterial subtypes. [PDF]
Han S +6 more
europepmc +1 more source
Insights into the catalytic mechanism of formate dehydrogenases from different microbial sources
This integrated study combines experimental enzyme kinetics with QM/MM simulations to map the catalytic mechanisms of four formate dehydrogenases at the atomic level. This approach reveals the key determinants of catalytic efficiency and guides the rational design of biocatalysts for effective CO2 reduction—a crucial step towards sustainable ...
Laura Legnani +8 more
wiley +1 more source
Challenges and considerations for whole-genome-based antimicrobial resistance plasmid investigations. [PDF]
Beh JQ +4 more
europepmc +1 more source
ABSTRACT Aim Bacterial biofilms around the apex are crucial in disease progression and persistence of apical periodontitis. While intracanal biofilms initiate infection, extraradicular biofilms contribute to treatment resistance and persistence. Thus, a comprehensive understanding of these biofilms may help elucidate mechanisms underlying persistent ...
Yoko Asahi +11 more
wiley +1 more source

