Results 241 to 250 of about 78,893 (337)

An archaeal virus capable of hydrolyzing the surface glycan of the host cell

mLife, EarlyView.
Wanjuan Yuan, Caixia Pei, Junkai Huang, Hongyu Chen, Juanying Fan, Cheng Jin, Li Huang   +6 more
wiley   +1 more source

Nature Inspired Delivery Vehicles for CRISPR‐Based Genome Editing

Small, EarlyView.
The review highlights nature‐inspired nanocarriers for CRISPR delivery, emphasizing viral vectors, extracellular vesicles, liposomes, and lipid nanoparticles. It discusses their roles in improving specificity, minimizing immunogenicity, and overcoming barriers in genome editing. Recent advancements, challenges, and therapeutic applications are explored,
Elizabeth Maria Clarissa, Mamata Karmacharya, Hyunmin Choi, Sumit Kumar, Yoon‐Kyoung Cho   +4 more
wiley   +1 more source

High activity and specificity of bacteriophage cocktails against carbapenem-resistant Klebsiella pneumoniae belonging to the high-risk clones CG258 and ST307. [PDF]

Front Microbiol
Tellez-Carrasquilla S, Salazar-Ospina L, Jiménez JN.   +2 more
europepmc   +1 more source

Liposome‐Based Interventions in Knee Osteoarthritis

Small, EarlyView.
Liposomes offer new opportunities for the management of knee osteoarthritis (OA). This review examines the last decade's advances, focusing on intra‐articularly (IA) administered liposomes and liposome‐based systems as pharmaceutical carriers and lubricants, while discussing their in vivo efficacy. Functionalized liposomes (with polymers, peptides etc.)
Evgenia Mitsou, Jacob Klein
wiley   +1 more source

Genome sequences of <i>Klebsiella pneumoniae</i> bacteriophages SF_KL2 and SF_KL25. [PDF]

Microbiol Resour Announc
Lorenz S, Abreu G, Oliveira H.
europepmc   +1 more source

Understanding of endo/lysosomal escape of nanomaterials in biomedical application

Smart Molecules, EarlyView.
This review summarized mainstream mechanisms of endo/lysosomal escape and design strategies of endo/lysosomal escapable nanoparticles in view of surface charge, polarity & hydrophobicity, particle morphology, and lysosomal escape agents. The utilization of endo/lysosomal escapable nanoparticles for vaccine delivery and genetic engineering are ...
Xin Wang, Haoyu Li, Chen Chen, Zhihui Liang   +3 more
wiley   +1 more source

Isolation and characterization of bacteriophage against clinical isolates of AmpC beta lactamase-Producing Klebsiella pneumoniae from hospital wastewater. [PDF]

PLoS One
Abusalah MAHA, Abusalah MAHA, Yean Yean C, Aziah I, Zaidah AR.   +4 more
europepmc   +1 more source

Machine Learning‐Assisted Prediction and Generation of Antimicrobial Peptides

Small Science, EarlyView.
A machine learning‐based in silico predictive and generative model is developed to engineer highly effective antimicrobial peptides (AMPs) for combating multidrug‐resistant pathogens. An iterative algorithm involving peptide generation, scoring, and motif identification produces AMPs with high theoretical scores.
Sukhvir Kaur Bhangu, Nicholas Welch, Morgan Lewis, Fanyi Li, Brint Gardner, Helmut Thissen, Wioleta Kowalczyk   +6 more
wiley   +1 more source

Complete genome sequences of 14 lytic bacteriophages against <i>Acinetobacter baumannii</i> from Kenya belonging to the genera <i>Obolenskvirus</i> and <i>Friunavirus</i>. [PDF]

Microbiol Resour Announc
Mwai F, Kigen C, Makobe C, Mutai I, Georges M, Odoyo E, Gachoya M, Musila L.   +7 more
europepmc   +1 more source

Redesign of Translocon EXP2 Nanopore for Detecting Peptide Fragments

Small Methods, EarlyView.
Nanopore sensing using the EXP2 nanopore from Plasmodium falciparum is enhanced by engineering mutants to reduce electrical noise and improve peptide detection. The EXP2ΔD231 mutant showed over 50% noise reduction and successfully discriminated diverse peptides, highlighting its potential for protein sequencing.
Mitsuki Miyagi, Misa Yamaji, Nina Kurokawa, Masafumi Yohda, Ryuji Kawano   +4 more
wiley   +1 more source