Results 91 to 100 of about 29,478 (285)

Stabilized Ion Selectivity Corrects Activation Drift in Kalium Channelrhodopsins

open access: yesAdvanced Science, Volume 13, Issue 6, 30 January 2026.
As newly emerged optogenetic tools, potassium channelrhodopsins (KCRs) can drift from inhibition to activation during illumination as K⁺ selectivity declines. It is shown that both the absolute K⁺/Na⁺ permeability ratio and its stability over time govern this drift, identify KCR1‐C29D as a reliably inhibitory variant, and outline design principles for ...
Xiao Duan   +14 more
wiley   +1 more source

Lipid composition of integral purple membrane by 1H and 31P NMR

open access: yesJournal of Lipid Research, 2005
In the purple membrane (PM) of halobacteria, lipids stabilize the trimeric arrangement of bacteriorhodopsin (BR) molecules and mediate the packing of the trimers in a regular crystalline arrangement.
Christian Renner   +2 more
doaj   +1 more source

Strategies for mitigating radiation damage and improving data completeness in 3D electron diffraction of protein crystals

open access: yesActa Crystallographica Section D, Volume 82, Issue 1, Page 11-22, January 2026.
This work demonstrates that multi‐position data acquisition mitigates radiation damage in electron diffraction of three‐dimensional protein crystals and that merging data from selected crystals in distinct orientations enhances completeness. Application of the two approaches enables high‐quality structural models to be obtained from limited or ...
Alaa Shaikhqasem   +8 more
wiley   +1 more source

Ionic Polymer Microactuator Activated by Photoresponsive Organic Proton Pumps

open access: yesActuators, 2015
An ionic polymer microactuator driven by an organic photoelectric proton pump transducer is described in this paper. The light responsive transducer is fabricated by using molecular self-assembly to immobilize oriented bacteriorhodopsin purple membrane ...
Khaled M. Al-Aribe   +2 more
doaj   +1 more source

Structural studies of bacteriorhodopsin in BC era

open access: yesBiophysics and Physicobiology, 2023
It marked half a century since the discovery of bacteriorhodopsin two years ago. On this occasion, I have revisited historically important diffraction studies of this membrane protein, based on my recollections. X-ray diffraction and electron diffraction,
Mikio Kataoka
doaj   +1 more source

The Bacterial Photosynthetic Reaction Center as a Model for Membrane Proteins [PDF]

open access: yes, 1989
Membrane proteins participate in many fundamental cellular processes. Until recently, an understanding of the function and properties of membrane proteins was hampered by an absence of structural information at the atomic level.
Allen, J. P.   +4 more
core   +1 more source

Hard‐Wired Solid‐State Bioelectronic Micropore Devices: Permanent Metal‐Protein‐Metal Junction Proof‐of‐Concept

open access: yesSmall, Volume 21, Issue 49, December 10, 2025.
A bottom‐up way to fabricate precisely engineered micropore solid‐state metal substrate/protein film / evaporated metal structures is shown to be a versatile platform for systematic electron transport measurements. As protein function is preserved and the junctions are thermally stable, down to 10K, such junctions can be useful for bioelectronic ...
Sudipta Bera   +12 more
wiley   +1 more source

Entwicklung künstlicher Mitochondrien mit selbstverstärkender Protonenerzeugung für die autonome Energieversorgung und metabolische Kopplung in künstlichen Zellen

open access: yesAngewandte Chemie, Volume 137, Issue 48, November 24, 2025.
Ein ATP‐Generator, der Mitochondrien nachahmt, verbessert die Enzyminstabilität von enzymbasierten künstlichen Mitochondrien und beseitigt die Toxizität von H2O2 durch quantitative Enzym‐Co‐Kompartimentierung. Die resultierenden künstlichen Mitochondrien können einen nachhaltigen Protonengradienten für die ATP‐Synthese aufbauen.
Fangqin Fu   +7 more
wiley   +1 more source

Charge transport in bacteriorhodopsin monolayers: The contribution of conformational change to current-voltage characteristics

open access: yes, 2009
When moving from native to light activated bacteriorhodopsin, modification of charge transport consisting of an increase of conductance is correlated to the protein conformational change.
Alfinito, Eleonora, Reggiani, Lino
core   +1 more source

Atomistic Insight into the Role of Threonine 127 in the Functional Mechanism of Channelrhodopsin-2 [PDF]

open access: yes, 2019
Channelrhodopsins (ChRs) belong to the unique class of light-gated ion channels. The structure of channelrhodopsin-2 from Chlamydomonas reinhardtii (CrChR2) has been resolved, but the mechanistic link between light-induced isomerization of the ...
Bamann, Christian   +9 more
core   +1 more source

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