Results 141 to 150 of about 85,232 (242)

Microbiome‐Based Modeling of CAR‐T Therapy Response in Lymphoma: Insights From Shotgun Metagenomics Sequencing

European Journal of Haematology, EarlyView.
ABSTRACT The interplay between the commensal microbiota and the mammalian immune system may influence the outcomes of T cell‐driven cancer immunotherapies. However, clinical studies supporting microbiota‐based interventions in chimeric antigen receptor T‐cell (CAR‐T) therapy remain scarce.
Rafael Hernani, Eliseo Albert, Carlos Hernani‐Morales, Sheila Zúñiga, Ana Benzaquén, Laura González‐Castillo, Ester Colomer, Júlia Morell, José Francisco Català‐Senent, José Luis Piñana, Estela Giménez, Ariadna Pérez, Juan Carlos Hernández‐Boluda, Ignacio Arroyo, Marcos Rivada, Teresa Barber, Teresa Alemany, Enric Santacatalina, Pilar Rentero‐Garrido, María José Terol, Rafael Díaz, David Navarro, Carlos Solano   +22 more
wiley   +1 more source

Effects of tacrolimus treatment on the gut microbiota and metabolites in liver transplant recipients. [PDF]

PLoS One
Wang G, Liu L, Zhang H, Mao P, Lu S, Zhang X, Li X, Song C.   +7 more
europepmc   +1 more source

Targeting the microbiota‐miRNA‐protease axis: A new therapeutic avenue in melanoma

The FEBS Journal, EarlyView.
Modulation of extracellular matrix (ECM) turnover is central to melanoma progression and metastasis, driven largely by ECM proteases. This review highlights the epigenetic regulation of ECM proteases by microRNAs and their roles in melanoma growth, invasion, and immune modulation.
Elias N. Katsoulieris, Paraskevi Ioannou, Nikolaos A. Afratis   +2 more
wiley   +1 more source

Polymicrobial retroperitoneal abscess by Salmonella enteritidis and Bacteroides fragilis unmasking cecal cancer. [PDF]

Rev Soc Bras Med Trop
Chang CY.
europepmc   +1 more source

Microbiome of Apical Intracanal and Extraradicular Biofilms From the Same Roots of Teeth With Persistent Apical Periodontitis: An Observational Study

International Endodontic Journal, EarlyView.
ABSTRACT Aim Bacterial biofilms around the apex are crucial in disease progression and persistence of apical periodontitis. While intracanal biofilms initiate infection, extraradicular biofilms contribute to treatment resistance and persistence. Thus, a comprehensive understanding of these biofilms may help elucidate mechanisms underlying persistent ...
Yoko Asahi, Nanako Kuriki, Motoki Okamoto, Daisuke Motooka, Shota Nakamura, Hazuki Maezono, Kittipit Klanliang, Tsuyoshi Shimaoka, Tetsuya Iida, Shigeyuki Ebisu, Yuichiro Noiri, Mikako Hayashi   +11 more
wiley   +1 more source

Microbiome and metabolite biomarkers of CAR T-cell therapy outcomes in relapsed/refractory diffuse large B-cell lymphoma. [PDF]

Blood Adv
Yoon SE, Kang W, Cho J, Cho HJ, Chalita M, Oh HS, Hyun DW, Han S, Kim H, Sung H, Lee JY, Park B, Ryu KJ, Kim HY, Cho D, Kim WS, Kim SJ.   +16 more
europepmc   +1 more source

Periodontitis and Periodontal Conditions in Systemically Healthy Children and Adolescents

Journal of Clinical Periodontology, EarlyView.
ABSTRACT Objective To answer the PICoS question ‘in systemically healthy children and adolescents (Population), what are the main features of periodontitis, necrotising periodontal diseases (NPD) and other periodontal conditions (periodontal abscesses, endo‐periodontal lesions, traumatic occlusal forces, prosthesis‐ and tooth‐related factors ...
Inbar Eshkol‐Yogev, Nagore Ambrosio, Cheryl Somani, Elena Figuero, Lior Shapira, Janet Davies   +5 more
wiley   +1 more source

Impact of Diet and Drugs on Fecal Lachnoclostridium Gene Marker (m3) in Non‐Invasive Diagnosis of Colorectal Neoplasia

Journal of Gastroenterology and Hepatology, EarlyView.
ABSTRACT Background A novel bacterial gene marker, Lachnoclostridium (m3), has potential for non‐invasive diagnosis of colorectal cancer (CRC) and adenoma. Aim This study aims to determine the diagnostic performance of m3 in a multi‐center cohort and to examine the effect of diet and drugs on fecal m3 in subjects with colorectal neoplasia. Methods In a
Min Dai, Louis H. S. Lau, Haiyun Shi, Yang Sun, Xiaobo Li, Mengbin Li, Hui Wang, Raphaela I. Lau, Jessie Q. Y. Liang, Francis K. L. Chan, Siew C. Ng   +10 more
wiley   +1 more source

Modulating <i>Bacteroides</i> to boost anti-PD-1 immunotherapy in HCC. [PDF]

J Immunother Cancer
Qi X, Yang M, Liu X, Ma L, Kaifi JT, Ericsson AC, Kimchi ET, Staveley-O'Carroll KF, Li G.   +8 more
europepmc   +1 more source

Microbiota and clinical outcomes of implant‐supported full‐mandible dentures on patients with a history of periodontitis: A 5‐year prospective cohort study

Journal of Prosthodontics, EarlyView.
Abstract Purpose To characterize the microbiota of implant‐supported full‐mandible dentures and its correlation to clinical outcomes for up to 5 years after implant loading in patients with a history of periodontal disease. Materials and Methods Twelve individuals with a history of periodontitis (Stage IV and Grade B) received five immediate implants ...
Jefferson Antônio Gomes, Yumi Chokyu Del‐Rey, Alice Ramos de Freitas, Ivete Aparecida de Mattias Sartori, Cássio do Nascimento   +4 more
wiley   +1 more source