Results 81 to 90 of about 42,594 (252)

Gene-microbiota interactions contribute to the pathogenesis of inflammatory bowel disease [PDF]

, 2016
Inflammatory bowel disease (IBD) is associated with risk variants in the human genome and dysbiosis of the gut microbiome, though unifying principles for these findings remain largely undescribed.
Chu, Huitung, Cunha, Larissa D., Ernest, Peter B., Green, Douglas R., Kambal, Amal, Khosravi, Arya, Kusumawardhani, Indah P., Kwon, Alice H. K., Mayer, Anne E., Mazmanian, Sarkis K., McGovern, Dermot P. B., Shen, Yue, Targan, Stephan R., Vasconcelos, Anitilton C., Virgin, Herbt W., Wu, Wei-Li, Xavier, Ramnik J.   +16 more
core   +1 more source

Bacterial Involvement in Oral Squamous Cell Carcinoma and Potentially Malignant Oral Disorders

Oral Diseases, EarlyView.
ABSTRACT Objective To clarify the relationship between oral squamous cell carcinoma (OSCC), potentially malignant oral disease (OPMD), and bacterial flora using metagenomic analysis. Methods This cross‐sectional observational study included 50 patients in the control group and 77 patients with OPMDs, 41 with early OSCCs, and 20 with advanced OSCCs ...
Atsumu Koketsu, Satoshi Fukase, Toru Tamahara, Tatsuru Saito, Akiko Ito, Yutaro Higashi, Tomonari Kajita, Tsuyoshi Kurobane, Masaaki Miyakoshi, Masahiro Iikubo, Kazuki Kumada, Bin Li, Muneaki Shimada, Ritsuko Shimizu, Tetsu Takahashi, Kensuke Yamauchi, Tsuyoshi Sugiura   +16 more
wiley   +1 more source

Early intestinal Bacteroides fragilis colonisation and development of asthma

BMC Pulmonary Medicine, 2008
Background The 'hygiene hypothesis' suggests that early exposure to microbes can be protective against atopic disease. The intestinal microbial flora could operate as an important postnatal regulator of the Th1/Th2 balance.
Goossens Herman, Verhulst Stijn L, Nelen Vera, Vael Carl, Desager Kristine N   +4 more
doaj   +1 more source

Exploring the nexus: Clinical and physiological correlation between cardiovascular disease and colorectal cancer

Experimental Physiology, EarlyView.
Abstract Colorectal cancer (CRC) and cardiovascular disease (CVD) are leading causes of morbidity and mortality worldwide, traditionally studied as distinct pathologies. However, emerging evidence suggests a significant physiological and molecular overlap between these conditions, indicating that they might share common pathophysiological pathways. The
Mohamad Bashir, Ali Murtada, Matti Jubouri, Wael Awad, Ian Williams, Damian M. Bailey   +5 more
wiley   +1 more source

Intestinal microflora and body mass index during the first three years of life: an observational study

Gut Pathogens, 2011
Background Recent research on obesity has demonstrated that the intestinal microflora can have an important influence on host energy balance. The aim of the study was to investigate the relationship between the intestinal microflora and the body mass ...
Vael Carl, Verhulst Stijn L, Nelen Vera, Goossens Herman, Desager Kristine N   +4 more
doaj   +1 more source

Cephalosporinase Activity in Bacteroides fragilis [PDF]

Antimicrobial Agents and Chemotherapy, 1973
Cephalosporinase activity was demonstrated in all of 10 strains of Bacteroides fragilis investigated. Low rates of hydrolysis of cephalosporins (0.25 to 3.5 μmol of cephaloridine per h per 10 9 cells) were found, but no activity against penicillin substrates was detected.
V E, Del Bene, W E, Farrar
openaire   +2 more sources

Gut biogeography of the bacterial microbiota [PDF]

, 2016
Animals assemble and maintain a diverse but host-specific gut microbial community. In addition to characteristic microbial compositions along the longitudinal axis of the intestines, discrete bacterial communities form in microhabitats, such as the gut ...
Donaldson, Gregory P., Lee, S. Melanie, Mazmanian, Sarkis K.   +2 more
core   +1 more source

Exploring the Key Role of Nanotechnology on Intratumoral Microbiome Modulation for Cancer Immunotherapy

MedComm – Biomaterials and Applications, Volume 5, Issue 1, March 2026.
The review provides a comprehensive analysis of microbiome‐mediated oncogenic mechanisms in various cancers, emphasizing the unique therapeutic strategies facilitated by nanotechnology. It aims to fill this gap by systematically reviewing nanotechnology‐driven strategies for microbiome elimination, with a focus on their ability to improve the cold TME ...
Yumei Gan, Yan Zhang, Xia Dong, Feng Lv
wiley   +1 more source

Gut microbiota utilize immunoglobulin A for mucosal colonization [PDF]

, 2018
The immune system responds vigorously to microbial infection while permitting lifelong colonization by the microbiome. Mechanisms that facilitate the establishment and stability of the gut microbiota remain poorly described.
Bjorkman, P. J., Chou, W.-C., Conner, M. E., Donaldson, G. P., Earl, A. M., Knight, R., Ladinsky, M. S., Mazmanian, S. K., Sanders, J. G., Yoo, B. B., Yu, K. B.   +10 more
core   +1 more source

Crosstalk Between Intratumoral Microbes and Tumor Immunity: Implications for Tumor Therapy

Cancer Medicine, Volume 15, Issue 2, February 2026.
ABSTRACT Background Emerging studies indicate that microbes are present in tumor cells and immune cells. Intratumoral microbiota (ITM) constitute an important component of the tumor immune microenvironment (TIME) and have an important impact on tumor progression and treatment. Objective Through the general elaboration of ITM represented by bacteria and
Fengxue Li, Lili Qiao, Xinquan Liang, Yingying Zhang, Ning Liang, Jian Xie, Guodong Deng, Yuying Hao, Pingping Hu, Xue Wu, Fangjie Ding, Can Feng, Yiming Mu, Jiandong Zhang   +13 more
wiley   +1 more source