Results 81 to 90 of about 23,608 (192)

Preferential Packing of Acidic Glycosidases and Proteases into Bacteroides Outer Membrane Vesicles

mBio, 2014
Outer membrane vesicles (OMV) are spherical membranous structures released from the outer membrane (OM) of Gram-negative bacteria. OMV have been proposed to play several different roles during both pathogenesis and symbiosis.
Wael Elhenawy, Mykhaylo O. Debelyy, Mario F. Feldman   +2 more
doaj   +1 more source

The Impact of Oral‐Gut Microbiota Structure and Its Manipulation on RA Development and Management

Food Science &Nutrition, Volume 14, Issue 8, August 2026.
(A) Schematic representation of oral–gut microbiota composition in health and rheumatoid arthritis (RA), highlighting the enrichment of beneficial microorganisms (green) under healthy conditions and the expansion of pathogenic microorganisms (orange) in RA‐associated dysbiosis.
Parisa Ahmadi, Mahmoud Mahmoudi, Sina Mozaffari‐Jovin, Ramiar Kamal Kheder, Tola Abdulsattar Faraj, Samaneh Mollazadeh, Jafar Hajavi, Hanieh Kolahdooz, Seyed‐Alireza Esmaeili   +8 more
wiley   +1 more source

The search for conjugative transposon in rumen bacterium Prevotella bryantii B14

Acta Agriculturae Slovenica, 2009
Only few plasmids and bacteriophages have been described to date in ruminal prevotella strains, therefore it appears plausible that the genetic exchange in these organisms must exploit other routes.
Gregor GORENC, Tomaž ACCETTO, Gorazd AVGUŠTIN   +2 more
doaj   +1 more source

Advancing Tumor Treatment Through Artificial Intelligence and Mathematical Modeling: A Comprehensive Review

Health Science Reports, Volume 9, Issue 8, August 2026.
ABSTRACT Background and Aims Solid tumors emerge from uncontrolled cell division and interactions with neighboring cells that influence their growth and resistance to therapy. Anti‐cancer drugs are developed to disrupt these processes, but they often damage healthy cells, making treatment difficult to manage safely and effectively. As the global cancer
Mohsin Kamran, Abdul Majeed, A S M Rafiul Haque, Johari Yap Abdullah   +3 more
wiley   +1 more source

Bacteroidota inhibit microglia clearance of amyloid-beta and promote plaque deposition in Alzheimer’s disease mouse models

Nature Communications
The gut microbiota and microglia play critical roles in Alzheimer’s disease (AD), and elevated Bacteroides is correlated with cerebrospinal fluid amyloid-β (Aβ) and tau levels in AD.
Caroline Wasén, Leah C. Beauchamp, Julia Vincentini, Shuqi Li, Danielle S. LeServe, Christian Gauthier, Juliana R. Lopes, Thais G. Moreira, Millicent N. Ekwudo, Zhuoran Yin, Patrick da Silva, Rajesh K. Krishnan, Oleg Butovsky, Laura M. Cox, Howard L. Weiner   +14 more
doaj   +1 more source

The Dual Role of the Gut Microbiota in Cancer Chemoresistance

MicrobiologyOpen, Volume 15, Issue 4, August 2026.
Comparison between Microbiota and Cancer therapy. ABSTRACT Chemoresistance is one of the primary reasons that cancer chemotherapy fails to deliver successful treatment outcomes and contributes to poor overall survival rates for patients with cancer. New research has begun to shed light on the effects of the gut microbiome (GM).
Hamed Tahmasebi, Aisa Bahar, Meisam Khazaei, Mohammad Reza Arabestani   +3 more
wiley   +1 more source

MYC in Oncogenesis and Therapeutic Implications

MedComm, Volume 7, Issue 8, August 2026.
The MYC oncogene family (c‐MYC, N‐MYC, L‐MYC) functions as a central transcriptional hub orchestrating cancer progression through multiple interconnected pathways. This graphical abstract illustrates MYC's role as a multidimensional regulator positioned at the nexus of tumor microenvironment remodeling, metabolic reprogramming, and therapeutic ...
Na Zhang, Li Wei, Cuiping Tang, Peilong Lai, Wenbin Zhong, Hua You   +5 more
wiley   +1 more source

Crystal structure of endo‐β‐1,6‐galactanase from Streptomyces avermitilis

Acta Crystallographica Section D, Volume 82, Issue 8, Page 962-971, August 2026.
The crystal structure of S. avermitilis endo‐β‐1,6‐galactanase belonging to GH30 subfamily 5 reveals the first structural framework for endo‐β‐1,6‐galactanase. The β‐1,6‐galactobiose‐bound complex identifies the catalytic subsites and a distal secondary sugar‐binding site, providing insight into β‐1,6‐galactan recognition.Endo‐β‐1,6‐galactanases ...
Zui Fujimoto, Naomi Kishine, Toshihisa Kotake, Satoshi Kaneko   +3 more
wiley   +1 more source

CLINICAL SIGNIFICANCE OF PARIETAL MICROFLORA IN CHILDREN WITH NON-SPECIFIC ULCERATIVE COLITIS

Педиатрическая фармакология, 2010
One of the key factors driving the development of non-specific ulcerative colitis (NSUC) is the intestinal microflora. The dominant composition of the parietal microflora was studied (Clostridium coccoides, Clostridium leptum, Bacteroides fragilis ...
P.V. Shumilov, M.G. Ipatova, L.I. Kafarskaya, A.N. Shkoporov, A.S. Potapov   +4 more
doaj   +2 more sources

Gasdermin‐Mediated Pyroptosis: Novel Strategies Against Colorectal Cancer

Cancer Science, Volume 117, Issue 8, Page 2064-2084, August 2026.
Pyroptosis is a double‐edged sword in colorectal cancer (CRC): chronic low‐grade pyroptosis promotes tumor progression, whereas acute induction of pyroptosis in cancer cells triggers antitumor immunity and enhances therapeutic response. Targeting gasdermin‐mediated pyroptosis represents a promising strategy for CRC treatment.
Kaibo Guo, Yuqian Feng, Jiamin Lu, Nuerbiye Abudurexiti, Xinlei Zhou, Mengfan Wei, Song Zheng   +6 more
wiley   +1 more source