Results 191 to 200 of about 67,208 (298)

Characterization of the Human Blood Group Glycosyltransferases GTA and GTB for the Synthesis of Blood Group Antigens

open access: yesAdvanced Synthesis &Catalysis, Volume 368, Issue 8, 15 April 2026.
This study presents the highly efficient heterologous production of the human blood group glycosyltransferases GTA/R176A and GTB, along with their comprehensive biochemical and kinetic characterization. Tailored enzyme cascades, involving the bacterial fucosyltransferase FutC and GTA or GTB, generate milligram quantities of various blood group ABH ...
Katja Pöstges   +8 more
wiley   +1 more source

Factors influencing gut microbial colonization: A host-microbe-environment interaction perspective. [PDF]

open access: yesCurr Res Food Sci
Zhao Y   +7 more
europepmc   +1 more source

Intratumoral fungal burden of Candida tropicalis as a novel prognostic biomarker for recurrence and mortality in colorectal cancer

open access: yesCancer, Volume 132, Issue 8, 15 April 2026.
ABSTRACT Background The crucial role of gut fungus dysbiosis in the carcinogenesis and progression of colorectal cancer (CRC) has recently garnered increasing attention. In this study, the potential role of Candida tropicalis, commensal gut fungi, in predicting CRC prognosis was investigated.
Sakiko Oba   +10 more
wiley   +1 more source

Inulin‐Based Oral Chemotherapy Modulates Gut Microbiota and Immune Microenvironment through Inhibition of Neutrophil Extracellular Trap Formation for Improving Cancer Therapy

open access: yesAdvanced Science, Volume 13, Issue 20, 9 April 2026.
Schematic representation of ZIF‐8@OXA@inulin for cancer immunotherapy. Synthesis of ZIF‐8@OXA@inulin. Augmentation of pyroptosis, regulation of gut microbiota, and inhibition of NETs formation by ZIF‐8@OXA@inulin‐mediated comprehensive strategy for antitumor immune response. ABSTRACT Despite the potential of chemoimmunotherapy against colorectal cancer
Zhenhao Li   +8 more
wiley   +1 more source

Effects of NaHCO3 Alkalinity Stress on Micropterus salmoides

open access: yesAquaculture, Fish and Fisheries, Volume 6, Issue 2, April 2026.
ABSTRACT To provide guidance for the actual cultivation of Micropterus salmoides in saline alkali environment, the effects of NaHCO3 alkalinity stress on enzymatic activity, tissue structure and gut microbiota were investigated. The experimental groups consisted of Group 1 (no NaHCO3 added), Group 2 (10 mmol/L NaHCO3 alkalinity) and Group 3 (30 mmol/L ...
Wen‐ping Jiang   +7 more
wiley   +1 more source

Decoding the Pathophysiology of Autoimmune Diseases—Mechanism, Triggers, and Nanotherapeutics: A Review

open access: yesAdvanced NanoBiomed Research, Volume 6, Issue 4, April 2026.
This review highlights how autoimmune diseases arise from intertwined immunological, genetic, and environmental factors, emphasizing gut microbiota dysbiosis as a pivotal driver. It outlines emerging nanotechnology‐based strategies—such as liposomes, hydrogels, and polymeric nanoparticles—that enhance targeted drug delivery, minimize systemic toxicity,
Md. Meraj Ansari   +5 more
wiley   +1 more source

Polyphenol‐Based Biomaterials Against Cancer Radio/Chemotherapy‐Induced Intestinal Toxicity

open access: yesAdvanced NanoBiomed Research, Volume 6, Issue 4, April 2026.
Radiotherapy/chemotherapy often causes intestinal toxicity, impairing cancer patients’ quality of life and treatment efficacy. Polyphenols protect against this injury via multiple mechanisms, but face oral use limitations. This review outlines their protective mechanisms and delivery challenges, highlighting recent oral delivery advances and future ...
Jixu Lu   +4 more
wiley   +1 more source

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