Results 71 to 80 of about 232,449 (132)

Cyclin A1 expression and associations with disease characteristics in childhood acute lymphoblastic leukemia.

, 2006
A critical cell cycle regulatory protein, cyclin A1, has been implicated in the development of acute myeloid leukemia (AML). Here, we have examined the expression and clinical significance of cyclin A1 in childhood acute lymphoblastic leukemia (ALL ...
Øra, Ingrid, Persson, Jenny L, Persson, Jenny L.,, Brunhoff, Cecilia, Landberg, Göran, Holm, Caroline, Ora, Ingrid, Anagnostaki, Lola, Wigerup, Caroline   +8 more
core   +1 more source

Experiences with health care and health-related quality of life of patients with hematologic malignancies in Mexico. [PDF]

BMC Health Serv Res, 2020
Doubova SV, Terreros-Muñoz E, Delgado-Lòpez N, Montaño-Figueroa EH, Infante-Castañeda C, Pérez-Cuevas R.   +5 more
europepmc   +1 more source

Parthenolide eliminates leukemia-initiating cell populations and improves survival in xenografts of childhood acute lymphoblastic leukemia [PDF]

, 2013
Blair, Allison, Moppett, John P, Diamanti, Paraskevi, Cox, Charlotte V   +3 more
core   +1 more source

Association of race/ethnicity with innate immune tumor microenvironment of children with B-acute lymphoblastic leukemia

Journal for ImmunoTherapy of Cancer, 2022
Kavita Dhodapkar, Julie R Gilbert, Himalee S Sabnis, Roman Radzievski, Deon B Doxie, Deborah DeRyckere, Sharon M Castellino   +6 more
doaj   +1 more source

Studies of FLT3 mutations in paired presentation and relapse samples from patients with acute myeloid leukemia: implications for the role of FLT3 mutations in leukemogenesis, minimal residual disease detection, and possible therapy with FLT3 inhibitors [PDF]

, 2002
FLT3 mutations, either internal tandem duplications (ITDs) or aspartate residue 835 (D835) point mutations, are present in approximately one third of patients with acute myeloid leukemia (AML) and have been associated with an increased relapse rate.
Kottaridis, P.D., Gale, R.E., Bowen, D.T., Langabeer, S.E., Frew, M.E., Linch, D.C.   +5 more
core  

Elucidating the role of the tumor suppressor Protein Phoshatase 2A in Chronic Myeloid Leukemia. [PDF]

, 2010
Protein phosphatase-2A (PP2A) is one of the major cellular serine-threonine phosphatases and is involved in the regulation of cell homeostasis through the negative regulation of signaling pathways initiated by protein kinases.
Neviani, Paolo
core  

Subclassification of B-acute lymphoblastic leukemia according to age, immunophenotype and microenvironment, predicts MRD risk in Mexican children from vulnerable regions

Frontiers in Oncology
IntroductionThe decisive key to disease-free survival in B-cell precursor acute lymphoblastic leukemia in children, is the combination of diagnostic timeliness and treatment efficacy, guided by accurate patient risk stratification.
Rubí Romo-Rodríguez, Gabriela Zamora-Herrera, Gabriela Zamora-Herrera, Jebea A. López-Blanco, Lucero López-García, Arely Rosas-Cruz, Laura Alfaro-Hernández, Laura Alfaro-Hernández, César Omar Trejo-Pichardo, Dulce Rosario Alberto-Aguilar, Dulce Rosario Alberto-Aguilar, Diana Casique-Aguirre, Diana Casique-Aguirre, Armando Vilchis-Ordoñez, Armando Vilchis-Ordoñez, Juan Carlos Solis-Poblano, Lilia Adela García-Stivalet, Vanessa Terán-Cerqueda, Nuria Citlalli Luna-Silva, Miguel Ángel Garrido-Hernández, Lena Sarahí Cano-Cuapio, Karen Ayala-Contreras, Fabiola Domínguez, María de los Ángeles del Campo-Martínez, Gerardo Juárez-Avendaño, Juan Carlos Balandrán, Sonia Mayra Pérez-Tapia, Carlos Fernández-Giménez, Pedro A. Zárate-Rodríguez, Enrique López-Aguilar, Aurora Treviño-García, Célida Duque-Molina, Laura C. Bonifaz, Juan Carlos Núñez-Enríquez, Mariana Cárdenas-González, Elena R. Álvarez-Buylla, Dalia Ramírez-Ramírez, Rosana Pelayo, Rosana Pelayo   +38 more
doaj   +1 more source

Tyrosine Kinase Inhibitor Post-Allogeneic Stem Cell Transplantation in Adult Philadelphia-Positive B-Acute Lymphoblastic Leukemia: State of the Art and Future Directions

Current Issues in Molecular Biology
In a scenario characterized by continuous improvement in outcomes, Philadelphia chromosome-positive (Ph+) ALL, once considered a biologically defined subtype with one of the poorest prognoses, now includes patients achieving long-term survival even ...
Martina Canichella, Paolo de Fabritiis
doaj   +1 more source

Estudo da associação de genes e proteínas de resistência a múltiplos fármacos (abcb1/ABCB1, abcc1/ABCC1 e lrp/LRP) com marcadores moleculares em pacientes portadores de leucemias agudas [PDF]

, 2013
Tese (doutorado) - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde, Programa de Pós-Graduação em Farmácia, Florianópolis, 2013.Menos de 45% dos portadores de leucemias agudas (LAs) sobrevivem cinco anos após o diagnóstico. O insucesso
Moraes, Ana Carolina Rabello de
core  

Case report: A familial B-acute lymphoblastic leukemia associated with a new germline pathogenic variant in PAX5. The first report in Mexico

Frontiers in Oncology
B-cell acute lymphoblastic leukemia (B-ALL) is one of the most common childhood cancers worldwide. Although most cases are sporadic, some familial forms, inherited as autosomal dominant traits with incomplete penetrance, have been described over the last
Joaquín García-Solorio, Octavio Martínez-Villegas, Ulises Rodríguez-Corona, Carolina Molina-Garay, Marco Jiménez-Olivares, Karol Carrillo-Sanchez, Elvia C. Mendoza-Caamal, Anallely Muñoz-Rivas, Beatriz E. Villegas-Torres, Alejandra Cervera, Luis L. Flores-Lagunes, Carmen Alaez-Verson   +11 more
doaj   +1 more source