Results 31 to 40 of about 18,272 (219)

Multifunctional BAF-1 [PDF]

open access: yesThe Journal of Cell Biology, 2007
![][1] Failure to form a nice neat seam (arrow, left) is just one of the many late-in-life defects of worms that lack BAF (right). Nuclear assembly happens every cell division.
openaire   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

open access: yesMolecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla   +4 more
wiley   +1 more source

FGF13 Deficiency Ameliorates Paclitaxel‐Induced Neuropathic Pain by Inhibiting VASH1‐Mediated Microtubule Detyrosination to Promote Mitophagy

open access: yesAdvanced Science, EarlyView.
FGF13 is upregulated in DRG neurons of PIPNP model mice. DRG neuron‐specific knockout of FGF13 ameliorates PIPNP symptoms. Mechanistically, FGF13 potentiates microtubule detyrosination by promoting VASH1 binding to microtubules. FGF13 knockout suppresses VASH1‐mediated microtubule detyrosination and promotes α‐tubulin tyrosination.
Yiming Dong   +10 more
wiley   +1 more source

Performance–Complexity Trade‐Offs in Battery Lifetime Prediction with Task‐Aware Transformers

open access: yesAdvanced Science, EarlyView.
FAST‐BatPro integrates convolutional feature extraction, flash Attention, and sparse attention for efficient battery lifetime prediction. Using limited early‐cycle data across multiple chemistries and operating conditions, it achieves robust accuracy while reducing inference latency, computational cost, and energy consumption.
Jingyuan Zhao   +9 more
wiley   +1 more source

Materials‐Guided Gene‐Ionizable Lipid Nanoparticles to Reverse Iron‐Associated Immune Resistance in Renal Cancer

open access: yesAdvanced Science, EarlyView.
ABSTRACT Iron overload is a common metabolic disturbance in cancer and contributes to poor outcomes in renal cell carcinoma (RCC), yet its effects on the tumour immune microenvironment remain unclear. Here we identify a previously unrecognized immunosuppressive axis in which iron overload downregulates the palmitoyltransferase ZDHHC12 in CD8+ T cells ...
Xin Jin   +16 more
wiley   +1 more source

A New Approach to Quantifying Bioaccumulation of Elements in Biological Processes

open access: yesBiology, 2021
Bioaccumulation, expressed as the bioaccumulation factor (BAF), is a phenomenon widely investigated in the natural environment and at laboratory scale.
Kinga Proc   +3 more
doaj   +1 more source

Extra Climate Benefits From Afforestation Due to Reduced Forest Fragmentation in China

open access: yesAdvanced Science, EarlyView.
Afforestation in China reduced forest fragmentation in 2015, transforming 51.8 M ha of edge forests into interior forests. This enhanced carbon sequestration (1.4±0.2 Pg CO2e, a cooling biogeochemical effect), while reduced albedo (−0.9 Pg CO2e, a warming biophysical effect) partially offset the gain, yielding a net extra climate benefit of ...
Nan Meng   +19 more
wiley   +1 more source

Research on System Optimizing of AAO-BAF Wastewater Treatment Process

open access: yesE3S Web of Conferences, 2018
To meet the more strict discharging standard, some combined processes have emerged to realize denitrification and phosphorus removal of wastewater more efficiently. Among them, AAO-BAF combined process was an efficient one.
Zhang Shoubin   +5 more
doaj   +1 more source

Application of big BAF sampling for estimating carbon on small woodlots

open access: yesForest Ecosystems, 2019
Background To accurately and efficiently quantify forest carbon stocks, a good forest inventory using appropriate sampling that minimizes costs and human effort is needed for landowners who want to enter carbon offset markets.
Yingbing Chen   +4 more
doaj   +1 more source

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