Results 81 to 90 of about 63,521 (249)
Medicinal Research Reviews, EarlyView.ABSTRACT CRISPR‐Cas9 genome‐wide screening has been instrumental towards identifying novel targets for drug discovery in cancer research. However, much of this research has centred specifically on adult cancers, with paediatric cancers being underserviced by current research and screening.
Steven He +2 more
wiley +1 more source
Cryo-EM structures of the BAF-Lamin A/C complex bound to nucleosomes
Nature CommunicationsBarrier-to-autointegration factor (BAF) associates with mitotic chromosomes and promotes nuclear envelope assembly by recruiting proteins, such as Lamins, required for the reconstruction of the nuclear envelope and lamina.
Naoki Horikoshi +5 more
doaj +1 more source
A Bodai Agyagkő Formáció (BAF) ásvány-kőzettani jellemzése és diagenezisének előzetes vázlata [PDF]
, 2013 Az eddigi kutatások alapján a Bodai Agyagkő Formációt perspektivikus közegként tekintik a magyarországi nagyaktivitású radioaktív hulladék geológiai tárolójának a befogadására.
Máthé, Zoltán, Varga, Andrea
core
Impacts of reindeer grazing on phosphorus sorption and nutrient availability in a tundra site
Oikos, EarlyView.Reindeer Rangifer tarandus, a large circumpolar herbivore, can influence whether nitrogen (N) or phosphorus (P) is the primary limiting nutrient in tundra plant communities. Specifically, findings from a site in northern Scandinavia suggest that under conditions where reindeer grazing stimulates inorganic N availability, grazing may drive ecosystems ...
Jerzy Szejgis +5 more
wiley +1 more source
International Review of Law, 2017 يتناول هذا البحث موضوعًا غاية في الأهمية هو الإعلان القضائي ودور طرفي الخصومة، المدعي والمدعى عليه، في عملية الإعلان. حيث استحدث المشرع الإماراتي، بموجب القانون الاتحادي رقم 10 لسنة 2014 ، دورًا إيجابيًّا - لم يكن مقررًا في السابق - لطرفي الخصومة في ...
BAF Serhan
doaj
The EMBO JournalAlterations in the nuclear envelope are linked to a variety of rare diseases termed laminopathies. A single amino acid substitution at position 12 (A12T) of the human nuclear envelope protein BAF (Barrier to Autointegration Factor) causes Néstor ...
Raquel Romero-Bueno +7 more
doaj +1 more source
Cell Reports, 2015 BAF (Brg/Brm-associated factors) complexes play important roles in development and are linked to chromatin plasticity at selected genomic loci. Nevertheless, a full understanding of their role in development and chromatin remodeling has been hindered by ...
Ramanathan Narayanan +12 more
doaj +1 more source
Genetic analysis of primary lung interdigitating dendritic cell sarcomas
The Journal of Pathology, EarlyView.Abstract Interdigitating dendritic cell sarcomas (IDCSs) are rare tumors that commonly arise in the hematopoietic system and rarely outside. The genetic drivers of IDCS carcinogenesis are unknown; therefore, therapeutic options are limited. We investigated somatic gene mutations and copy‐number alterations (CNAs) in nine IDCSs arising in the lung by ...
Mikhail S Ermakov +6 more
wiley +1 more source
Thin Fluoride Insulators for Improved 2D Transistors: From Deposition Methods to Recent Applications
physica status solidi (RRL) – Rapid Research Letters, EarlyView.2D materials hold significant promise for next‐generation electronic and optoelectronic devices, but suitable gate dielectrics are still a challenge. Fluoride insulators, offering inert, dangling‐bond‐free surfaces, have recently emerged as strong candidates. This review covers recent publications on high‐quality fluoride thin‐film deposition and their
Behzad Dadashnia +3 more
wiley +1 more source
The Journal of Cell Biology, 2002 ![][1] BAF bridges DNA (binding at either end) and nuclear envelope proteins (binding in the middle). Barrier-to-autointegration factor (BAF) was first described as a cellular activity that prevents retroviral DNA from undergoing suicidal autointegration, but its function ...
openaire +2 more sources