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Role of HXXXD-motif/BAHD acyltransferases in the biosynthesis of extracellular lipids
Plant Cell Reports, 2014Terrestrial plants have evolved specific adaptations to preserve water and protect themselves from their environment. Such adaptations range from secondary metabolites and specialized structures that conduct water and nutrients, to cell wall modifications (i.e., cuticle and suberin) that prevent dehydration and provide a physical barrier to pathogens ...
Dylan Kosma, Isabel Molina
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Research progress of plant BAHD acyltransferase family
China Journal of Chinese Materia Medica, 2016Acylation conducted by acyltransferase is a ubiquitous process in structure modification of secondary metabolites. It plays an important role in the structural diversity of natural products and contributes significantly to their improved stabilities, increased solubilities, and enhanced bioavailabilities.
Yu-Yu, Liu +5 more
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A BAHD acyltransferase is expressed in the tapetum of Arabidopsis anthers and is involved in the synthesis of hydroxycinnamoyl spermidines [PDF]
Plant Journal, 2009 SummaryBAHD acyltransferases catalyze the acylation of many plant secondary metabolites. We characterized the function of At2g19070, a member of the BAHD gene family of Arabidopsis thaliana. The acyltransferase gene was shown to be specifically expressed in anther tapetum cells in the early stages of flower development.
Thierry Heitz, Sébastien Besseau
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Plant Molecular Biology, 2009
Plant acyl-CoA dependent acyltransferases constitute a large specific protein superfamily, named BAHD. Using the conserved sequence motifs of BAHD members, we searched the genome sequences of Populus and Arabidopsis, and identified, respectively, 94- and 61-putative genes.
Chang-Jun Liu +2 more
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Plant acyl-CoA dependent acyltransferases constitute a large specific protein superfamily, named BAHD. Using the conserved sequence motifs of BAHD members, we searched the genome sequences of Populus and Arabidopsis, and identified, respectively, 94- and 61-putative genes.
Chang-Jun Liu +2 more
exaly +3 more sources
Plant Cell, 2018 Plant specialized metabolism serves as a rich resource of biologically active molecules for drug discovery. The acylated flavonol glycoside montbretin A (MbA) and its precursor myricetin 3-O-(6'-O-caffeoyl)-glucosyl rhamnoside (mini-MbA) are potent inhibitors of human pancreatic α-amylase and are being developed as drug candidates to treat type-2 ...
Seohyun Jo +2 more
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Planta, 2020
A BAHD terpene alcohol acyltransferase, CaAT20, was identified from Celastrus angulatus Maxim, expressed in E. coli and functionally characterized. S405A mutant of CaAT20 increased the enzyme activity. Acylation is a diversely physiological process in the biosynthesis of plant secondary metabolites. Plant BAHD acyltransferases play an important role in
Xiaoguang Yan +5 more
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A BAHD terpene alcohol acyltransferase, CaAT20, was identified from Celastrus angulatus Maxim, expressed in E. coli and functionally characterized. S405A mutant of CaAT20 increased the enzyme activity. Acylation is a diversely physiological process in the biosynthesis of plant secondary metabolites. Plant BAHD acyltransferases play an important role in
Xiaoguang Yan +5 more
openaire +2 more sources
2000
Enzymatic acylation is a widespread substitution reaction that is notably involved in the diversification of natural substances produced by plant secondary metabolism. Acylation may also trigger nonenzyme-catalyzed reactions in natural product biosynthesis.
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Enzymatic acylation is a widespread substitution reaction that is notably involved in the diversification of natural substances produced by plant secondary metabolism. Acylation may also trigger nonenzyme-catalyzed reactions in natural product biosynthesis.
openaire +1 more source