Advanced modification of drug nanocrystals by using novel fabrication and downstream approaches for tailor-made drug delivery [PDF]
Drug nanosuspensions/nanocrystals have been recognized as one useful and successful approach for drug delivery. Drug nanocrystals could be further decorated to possess extended functions (such as controlled release) and designed for special in vivo ...
Haipeng, Yin +3 more
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In Vitro effects of Plantago major extract, aucubin and baicalein on Candida albicans biofilm formation, metabolic activity and cell surface hydrophobicity [PDF]
Purpose To determine the in vitro effectiveness of Plantago major extract, along with two of its active components, aucubin and baicalein, on the inhibition of Candida albicans growth, biofilm formation, metabolic activity, and cell surface ...
Eckert, George J. +3 more
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Baicalin reduces inflammation to inhibit lung cancer via targeting SOCS1/NF-κB/STAT3 axis
Inflammation affects several aspects of lung cancer progression including cell proliferation, metastasis, apoptosis, angiogenesis, and drug resistance.
Lijuan Guo +5 more
doaj +1 more source
Neuroprotective effect of baicalin on focal cerebral ischemia in rats
Baicalin, a flavonoid compound from the root of the herb Scutellaria baicalensis Georgi, has been widely used to treat patients with inflammatory disease.
Jiong Dai +8 more
doaj +1 more source
Effects of camptothecin derivatives and topoisomerase dual inhibitors on Trypanosoma cruzi growth and ultrastructure [PDF]
BACKGROUND: Trypanosoma cruzi is the etiological agent of Chagas’ disease that is an endemic disease in Latin America and affects about 8 million people.
Aline Araujo Zuma +4 more
core +1 more source
Baicalin alleviates lead-induced cognitive dysfunction by modulating apoptosis and autophagy in mice
Lead exposure is a well-documented environmental neurotoxin that poses a persistent threat to brain development. Excessive lead accumulation in this region impairs cognitive function and induces neuronal damage, yet effective therapeutic interventions ...
Jia Yu +6 more
doaj +1 more source
Wild mushroom extracts potentiate the action of standard antibiotics against multiresistant bacteria [PDF]
Aims: The main objective of the present work was to evaluate the capacity of wild mushroom extracts to potentiate the action of standard antibiotics, through synergisms that allow a decrease in their therapeutic doses and ultimately contribute to the ...
Alves, Maria José +6 more
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Transcriptome Sequencing Explores the Mechanism of Baicalin on Bone Cancer Pain
Aitao Wang,1 Dongmei Guo,1 Hongyu Cheng,2 Hui Jiang,3 Xiaojuan Liu,1 Zhizhong Yun4 1Department of Anesthesiology, Inner Mongolia People’s Hospital, Hohhot, Inner Mongolia, 010017, People’s Republic of China; 2Department of Anesthesiology, Inner Mongolia ...
Wang A +5 more
doaj
Preparation, characterisation and in vitro anti-inflammatory activity of Baicalin microsponges
Baicalin, a flavonoid extracted from traditional Chinese medicine, Scutellaria baicalensis has significant anti-inflammatory effects. Microsponges are drug delivery systems that improve drug stability and slow the release rate.
Miao Li +6 more
doaj +1 more source

