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Baicalin modulates metabolic and inflammatory proteins and attenuates neuronal damage in a rat model of ischemic stroke. [PDF]

J Vet Sci
Son HK, Park DJ, Kim HH, Kang JB, Koh PO.   +4 more
europepmc   +1 more source

Baicalin Mitigates <i>Pasteurella multocida</i>-Induced Pulmonary and Vascular Injury via NLRP3/COX-2 Inhibition in Mice. [PDF]

Animals (Basel)
Zhang D, Zhao C, Xue Y, Lu Q, Liu Y, Xiong J, Ye C, Fu S, Wu Z, Qiu Y, Guo P.   +10 more
europepmc   +1 more source

The Pharmacological Efficacy of Baicalin in Inflammatory Diseases

International Journal of Molecular Sciences, 2023
Baicalin is one of the most abundant flavonoids found in the dried roots of Scutellaria baicalensis Georgi (SBG) belonging to the genus Scutellaria. While baicalin is demonstrated to have anti-inflammatory, antiviral, antitumor, antibacterial, anticonvulsant, antioxidant, hepatoprotective, and neuroprotective effects, its low hydrophilicity and ...
Yazhou Wang, Chenxu Zhao, Baoyu Zhao
exaly   +4 more sources

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Baicalin and lung diseases

Naunyn-Schmiedeberg's Archives of Pharmacology, 2023
Studies focusing on natural products have been conducted worldwide, and the results suggest that their natural ingredients effectively treat a wide range of illnesses. Baicalin (BIA) is a glycoside derived from the flavonoid baicalein present in Scutellaria baicalensis of the Lamiaceae family.
Zeina W, Sharawi, Islam M, Ibrahim, Esraa K, Abd-Alhameed, Hanan S, Althagafy, Fatima A, Jaber, Steve, Harakeh, Emad H M, Hassanein   +6 more
openaire   +2 more sources

Baicalin, a natural LSD1 inhibitor

Bioorganic Chemistry, 2016
Baicalin is one of the active ingredients in the skullcap, with a variety of pharmacological effects, such as blood pressure reduction, sedation, liver-protection, gallbladder-protection, anti-bacteria, and anti-inflammation. In our study, baicalin was first characterized as a LSD1 inhibitor with an IC50 of 3.01μM and showed strong LSD1 inhibitory ...
Yi-Chao Zheng, Dan-Dan Shen, Li-Juan Zhao   +2 more
exaly   +3 more sources

Electrochemical investigations of baicalin and DNA?baicalin interactions

Analytical and Bioanalytical Chemistry, 2004
Baicalin is an anti-HIV drug purified from the traditional Chinese medicinal plant Scutellaria Baicalensis Georgi. Baicalin has proven to be electroactive at pyrolytic graphite (PG) electrodes. We thus studied its interaction with DNA via the electrochemical approach. We observed that the peak currents corresponding to the baicalin reduction-oxidation (
Ziyi, Sun, Zhong, Ma, Wenjun, Zhang, Xiaoyue, Wang, Chunhai, Fan, Genxi, Li   +5 more
openaire   +2 more sources