Results 181 to 190 of about 10,947 (224)
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Synthesis of baicalin-copper and baicalin-aluminium complex and its bioactivity
China Journal of Chinese Materia Medica, 2012Objective To study synthesis of baicalin-copper and baicalin-aluminium complex and its antimicrobial, anti-tumor activity and anti-tumor effect against macrophages. Method Baicalin was reacted with metallic salt under a weak base condition to produce baicalin-copper and baicalin-aluminium complex.
Yanji, Liu +7 more
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Hydroxylethylation of baicalin by γ-ray irradiation of baicalin in ethanol
Radiation Physics and Chemistry, 1996Via γ-irradiation of baicalin in ethanol, hydroxylethyl groups were introduced into B and C rings of baicalin. Eight hydroxylethylation products were separated by reverse HPLC and their molecular structures were postulated through their UV, IR, MS and fluorescence spectra. The primary binding constants of baicalin and its hydroxylethylation products in
Cai Zhongli, He Yongke, Wu Jilan
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Baicalin is a substrate of OATP2B1 and OATP1B3
Phytotherapy Research, 2018The use and significance of baicalin, the main bioactive component found in Radix Scutellaria, have been on the rise due to its interesting pharmacological properties. Baicalin, a low passive permeability compound, is directly absorbed from the upper intestine and its hepatic elimination is dominant.
Bernadett Kalapos‐Kovács +7 more
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Chrysin and baicalin in diabetic nephropathy
Environmental Toxicology and Pharmacology, 2017[no abstract available]
Chirumbolo, Salvatore, Bjørklund, Geir
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Theoretical investigation of the conformational space of baicalin
Journal of Molecular Graphics and Modelling, 2017Flavonoids are a large group of polyphenolic compounds ubiquitously present in plants. They are important components of human diet. They are recognized as potential drug candidates to be used in the treatment and prevention of a lot of pathological disorders, due to their protective effects.
Martínez Medina, Juan José +3 more
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Antiplatelet, anticoagulant, and profibrinolytic activities of baicalin
Archives of Pharmacal Research, 2014Baicalin is a flavonoid compound purified from the medicinal plant Scutellaria baicalensis Georgi and has been reported to possess anti-inflammatory and anti-viral activities. However, antiplatelet, anticoagulant, and profibrinolytic properties of baicalin have not been studied.
Wonhwa, Lee +2 more
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Baicalein and baicalin as Zika virus inhibitors
Archives of Virology, 2018At present, there is no effective antiviral agent for Zika virus (ZIKV), an arbovirus that is known for its teratogenic effects on newborns. Baicalein and baicalin were found to be capable of downregulating ZIKV replication up to 10 hours postinfection, while prophylactic effects were evident in pre-treated cells.
Oo, Adrian +4 more
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Efffect of baicalin on antipyresis and influence on cytokine
China Journal of Chinese Matera Medica, 2010To study the antipyretic effect of baicalin in inhibiting yeast-induced fever in rats and the influence on inflammatory cytokine, then explore the possible mechanism of baicalin in inhibiting yeast-induced fever in rats.Rat modles of pyrexia were established by subcutaneous injection of yeast (2 g x kg(-1)); the rats of were divided into the normal ...
Qiannan, Li, Xiaoqun, Ge
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Pharmacokinetics and Bioavailability Enhancement of Baicalin: A Review
European Journal of Drug Metabolism and Pharmacokinetics, 2018Baicalin is one of the major bioactive components of Scutellaria radix, a Chinese herb that has been used since ancient times. Baicalin has various pharmacological activities, including antitumor, antimicrobial, and antioxidant, and has wide clinical applications.
Ting, Huang +2 more
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Stability of baicalin in biological fluids in vitro
Journal of Pharmaceutical and Biomedical Analysis, 2005The stability of baicalin in buffered aqueous solutions at different pHs and in biological fluids, including plasma, urine and tissue homogenates, were investigated in vitro. Structures of the degradation products of baicalin were elucidated by liquid chromatography-electrospray ion trap mass spectrometry and the degradation mechanism was proposed with
Jie, Xing, Xiaoyan, Chen, Dafang, Zhong
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