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Absorption and enterohepatic circulation of baicalin in rats

Life Sciences, 2005
Pharmacokinetics of baicalin, in form of its parent drug (BG) and conjugated metabolites (BGM), were studied following intravenous and oral administration of baicalin to intact rats. The enterohepatic circulation of BG and BGM was also assessed in a linked-rat model.
Jie, Xing, Xiaoyan, Chen, Dafang, Zhong
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Study of baicalin scavenging hydroxyethyl peroxyl radicals by radiolysis of aerated ethanol-baicalin system

Radiation Physics and Chemistry, 1996
Abstract The reaction of baicalin (β- d -glucopyranosiduronic acid, 5,6-dihydroxy-oxo-2-phenyl-4H-1-benzopyran-7-yl) scavenging hydroxyethyl peroxyl radicals (RO 2 . ) was studied with the aid of radiolysis of aerated ethanol. Two main stable products were separated by reverse HPLC and their possible molecular structures were derived from their UV ...
null Cai Zhongli   +2 more
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[A histochemical study on baicalin].

Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2001
Baicalin in the root of Scutellaria baicalensis was analysed histochemically by means of TLC and HPLC. It was determined that the content of baicalin in phloem was 11.08%, in xylem 7.86%, in phellem 2.19% and in centric decayed part 0.815%. Thus the quality of root of Scutellaria baicalensis is believed to consist in thin phellem, high ratio of phloem ...
X, Du, B, Li, Y, Pan, , Mali
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Microbial transformation of baicalin and baicalein

Journal of Molecular Catalysis B: Enzymatic, 2007
Abstract As a result of microbial transformation of baicalin and baicalein the products of 4 -hydroxylation of the B ring, O -methylation at C-6, and both O -methylation at C-6 and hydroxylation at C-4 were obtained. Transformations of baicalin were accompanied by the reaction of hydrolysis.© 2007 Elsevier B.V. All rights reserved.
Edyta Kostrzewa-Susłow   +2 more
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Neuroprotective Mechanisms of Baicalin in Ischemia Stroke

ACS Chemical Neuroscience
Ischemic stroke (IS) remains one of the leading global causes of mortality and disability, imposing a substantial socioeconomic burden on families and healthcare systems. Despite recognition as a critical global health challenge, therapeutic interventions for cerebral ischemia remain severely limited.
Peng He   +5 more
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[Measurement of baicalin contents by HPLC].

Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2003
To compare the contents of baicalin in the raw medical material and the different prepared medical materials of Scutellaria baicalensis.The contents of baicalin were determined by HPLC. Chromatographic conditions included Hypersil C18 column and the mobile phase consisting of a mixture of methanol-0.04% phosphoric acid (46:54). Baicalin was detected at
Zhu-ying, He   +4 more
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[Study on anti-endotoxin of baicalin].

Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology, 2015
To study the anti-endotoxin of different concentration baicalin.6.250 microg/mL, 3.125 microLg/mL, 1.562 microg/mL and 0.781 microg/mL baicalin solutions were mixed with I EU/mL endotoxin, respectively. The mixtures were put into water of (37+/-1) degrees C for 15 min, 30 min and 60 min.
Yong-Qing, Dou   +3 more
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[Advance in studies on pharmacokinetics of baicalin].

Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2019
Scutellariae baicalensis is one of the most important traditional Chinese medicinal herbs, mainly distributed in Shandong and Hebei provinces. It has significant pharmacological effects such as antimicrobial activity, anti-inflammatory and antioxidation. Baicalin is one of its main effective components.
Hong-Chao, Zhou   +6 more
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Baicalin

2018
Li Li, Li Zhang, Guan-Hua Du
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Baicalin

Inpharma Weekly, 1992
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