Results 191 to 200 of about 11,830 (227)
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Antiplatelet, anticoagulant, and profibrinolytic activities of baicalin
Archives of Pharmacal Research, 2014Baicalin is a flavonoid compound purified from the medicinal plant Scutellaria baicalensis Georgi and has been reported to possess anti-inflammatory and anti-viral activities. However, antiplatelet, anticoagulant, and profibrinolytic properties of baicalin have not been studied.
Wonhwa, Lee +2 more
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Microbial transformation of baicalin and baicalein
Journal of Molecular Catalysis B: Enzymatic, 2007As a result of microbial transformation of baicalin and baicalein the products of 4′-hydroxylation of the B ring, O-methylation at C-6, and both O-methylation at C-6 and hydroxylation at C-4′ were obtained. Transformations of baicalin were accompanied by the reaction of hydrolysis.
Edyta Kostrzewa-Susłow +2 more
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[A histochemical study on baicalin].
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2001Baicalin in the root of Scutellaria baicalensis was analysed histochemically by means of TLC and HPLC. It was determined that the content of baicalin in phloem was 11.08%, in xylem 7.86%, in phellem 2.19% and in centric decayed part 0.815%. Thus the quality of root of Scutellaria baicalensis is believed to consist in thin phellem, high ratio of phloem ...
X, Du, B, Li, Y, Pan, , Mali
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Radiation Physics and Chemistry, 1996
Abstract The reaction of baicalin (β- d -glucopyranosiduronic acid, 5,6-dihydroxy-oxo-2-phenyl-4H-1-benzopyran-7-yl) scavenging hydroxyethyl peroxyl radicals (RO 2 . ) was studied with the aid of radiolysis of aerated ethanol. Two main stable products were separated by reverse HPLC and their possible molecular structures were derived from their UV ...
null Cai Zhongli +2 more
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Abstract The reaction of baicalin (β- d -glucopyranosiduronic acid, 5,6-dihydroxy-oxo-2-phenyl-4H-1-benzopyran-7-yl) scavenging hydroxyethyl peroxyl radicals (RO 2 . ) was studied with the aid of radiolysis of aerated ethanol. Two main stable products were separated by reverse HPLC and their possible molecular structures were derived from their UV ...
null Cai Zhongli +2 more
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Neuroprotective Mechanisms of Baicalin in Ischemia Stroke
ACS Chemical NeuroscienceIschemic stroke (IS) remains one of the leading global causes of mortality and disability, imposing a substantial socioeconomic burden on families and healthcare systems. Despite recognition as a critical global health challenge, therapeutic interventions for cerebral ischemia remain severely limited.
Peng He +5 more
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A chromatographic method for baicalin quantification in rat thalamus
Biomedical Chromatography, 2005AbstractA rapid reversed‐phase high‐performance liquid chromatographic (rp‐HPLC) assay for the determination of baicalin in rat thalamus was developed. This was carried out on a Hypersil –C18 column using 4‐nitro‐benzoic acid as the internal standard with a mobile phase of methanol–water–H3PO4 (45:55:0.2, v/v/v). Detection was by UV at 277 nm.
Lujun, Zhang +5 more
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[Measurement of baicalin contents by HPLC].
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2003To compare the contents of baicalin in the raw medical material and the different prepared medical materials of Scutellaria baicalensis.The contents of baicalin were determined by HPLC. Chromatographic conditions included Hypersil C18 column and the mobile phase consisting of a mixture of methanol-0.04% phosphoric acid (46:54). Baicalin was detected at
Zhu-ying, He +4 more
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[Advance in studies on pharmacokinetics of baicalin].
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2019Scutellariae baicalensis is one of the most important traditional Chinese medicinal herbs, mainly distributed in Shandong and Hebei provinces. It has significant pharmacological effects such as antimicrobial activity, anti-inflammatory and antioxidation. Baicalin is one of its main effective components.
Hong-Chao, Zhou +6 more
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[Study on anti-endotoxin of baicalin].
Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology, 2015To study the anti-endotoxin of different concentration baicalin.6.250 microg/mL, 3.125 microLg/mL, 1.562 microg/mL and 0.781 microg/mL baicalin solutions were mixed with I EU/mL endotoxin, respectively. The mixtures were put into water of (37+/-1) degrees C for 15 min, 30 min and 60 min.
Yong-Qing, Dou +3 more
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