Results 21 to 30 of about 974 (159)
Journal of Water and Health, 2021 The occurrence of potentially pathogenic free-living amoebae (FLA) in natural hot springs is considered a public health concern. FLAs are known to cause serious health outcomes to a wide spectrum of mammalian hosts. The present study aimed to provide the
Mary Rachael Leigh Fabros +6 more
doaj +1 more source
JMM Case Reports, 2016 Introduction: This case report describes a human survivor of Balamuthia mandrillaris infection. This is a free-living amoeba that can cause infection with the devastating consequence of near universally fatal encephalitis. We report this case to demonstrate the possibility of recovery.
Vollmer, Michael Eric, Glaser, Carol
openaire +2 more sources
BMC Infectious Diseases, 2023 Background Balamuthia granulomatous amoebic encephalitis (GAE) is a peculiar parasitic infectious disease of the central nervous system, about 39% of the infected Balamuthia GAE patients were found to be immunocompromised and is extremely rare clinically.
Jun Liu +6 more
doaj +1 more source
Successful Treatment of Balamuthia mandrillaris Granulomatous Amebic Encephalitis with Nitroxoline
Emerging Infectious Diseases, 2023 A patient in California, USA, with rare and usually fatal Balamuthia mandrillaris granulomatous amebic encephalitis survived after receiving treatment with a regimen that included the repurposed drug nitroxoline.
Natasha Spottiswoode +17 more
doaj +1 more source
Disseminated acanthamoebiasis in a horse
Brazilian Journal of Veterinary Pathology, 2020 Amoebic infections have been described in humans and animals, causing lesions in specific organs or as systemic infections. In both animals and humans, immunocompromised patients are predisposed to the infection.
Maria F. Gonzalez +2 more
doaj +1 more source
In Vitro Activity of Nitroxoline (5-Nitro-8-Hydroxyquinoline) Against Aspergillus Species. [PDF]
MycosesABSTRACT Background Nitroxoline is an old antibiotic currently approved for the treatment of uncomplicated urinary tract infections. Its mode of action is based on the chelation of bivalent cations, such as zinc. Objectives As zinc plays a central role in the metabolism of Aspergillus spp., we performed antifungal susceptibility testing against ...
Hoffmann A +7 more
europepmc +2 more sources
The transcriptome of Balamuthia mandrillaris trophozoites for structure-guided drug design
Scientific Reports, 2021 Balamuthia mandrillaris, a pathogenic free-living amoeba, causes cutaneous skin lesions as well as granulomatous amoebic encephalitis, a ‘brain-eating’ disease.
Isabelle Q. Phan +12 more
doaj +1 more source
Guidelines for the purification and characterization of extracellular vesicles of parasites
Journal of Extracellular Biology, Volume 2, Issue 10, October 2023., 2023 Abstract Parasites are responsible for the most neglected tropical diseases, affecting over a billion people worldwide (WHO, 2015) and accounting for billions of cases a year and responsible for several millions of deaths. Research on extracellular vesicles (EVs) has increased in recent years and demonstrated that EVs shed by pathogenic parasites ...
Carmen Fernandez‐Becerra +30 more
wiley +1 more source
Neuropathology, Volume 42, Issue 3, Page 190-196, June 2022., 2022 An 82‐year‐old man, who was healthy and had worked as a farmer, experienced worsening neurological symptoms over a seven‐month period, which eventually caused his death. Multiple fluctuating brain lesions were detected radiographically. Clinically, sarcoidosis was ranked high among the differential diagnoses because of the presence of skin lesions ...
Tatsuro Maehara +10 more
wiley +1 more source
Disseminated Balamuthia mandrillaris Infection [PDF]
Journal of Clinical Microbiology, 2015 ABSTRACTBalamuthia mandrillarisis a rare cause of human infection, but when infections do occur, they result in high rates of morbidity and mortality. A case of disseminatedBalamuthiainfection is presented. Early diagnosis and initiation of recommended therapy are essential for increased chances of successful outcomes.
Katherine R, Schafer +7 more
openaire +2 more sources