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Balamuthia mandrillaris is a pathogenic free-living amoeba that causes a rare but almost always fatal infection of the central nervous system called granulomatous amoebic encephalitis (GAE). Two distinct forms of B.
Matthew T. Laurie +9 more
doaj +1 more source
Balamuthia mandrillaris infection in China: a retrospective report of 28 cases
Balamuthia mandrillaris infection is a rare and fatal disease. We have recorded 28 cases of Balamuthia mandrillaris infection during the past 20 years. Eighteen patients (64%) were male and 10 (36%) were female. Patient age ranged from 3 to 74 (mean, 27)
Lei Wang +14 more
doaj +1 more source
Diagnosing Balamuthia mandrillaris encephalitis via next-generation sequencing in a 13-year-old girl
Balamuthia amoebic encephalitis has a subacute-to-chronic course and is almost invariably fatal owing to delayed diagnosis and a lack of effective therapy.
Xia Wu +6 more
doaj +1 more source
A 76‐year‐old male with multiple enhancing brain lesions
Brain Pathology, Volume 32, Issue 3, May 2022.
Kathryn L. Eschbacher +5 more
wiley +1 more source
Increasing Importance of Balamuthia mandrillaris [PDF]
SUMMARY Balamuthia mandrillaris is an emerging protozoan parasite, an agent of granulomatous amoebic encephalitis involving the central nervous system, with a case fatality rate of >98%. This review presents our current understanding of Balamuthia infections, their ...
Abdul, Matin +3 more
openaire +2 more sources
Fatal Balamuthia mandrillaris brain infection associated with improper nasal lavage
We report the case of a 69-year-old female who presented with a chronic nasal skin rash, new onset focal seizure, and a cerebral ring-enhancing lesion after a year of improper nasal irrigation.
Keenan J. Piper +5 more
doaj +1 more source
Balamuthia mandrillaris resistance to hostile conditions [PDF]
The resistance of Balamuthia mandrillaris to physical, chemical and radiological conditions was tested. Following treatments, viability was determined by culturing amoebae on human brain microvascular endothelial cells for up to 12 days. B. mandrillaris cysts were resistant to repeated freeze–thawing (five times), temperatures of up to 70 °C, 0.5 % SDS,
Ortega Rivas, Antonio +2 more
openaire +3 more sources
Balamuthia mandrillaris is an opportunistic, free-living ameba that is pathogenic to humans. It has a worldwide distribution but is mainly detected in warmer regions. Balamuthia infections are rare but have been reported in both immunocompetent and immunocompromised individuals of all ages. B.
Bhosale, Namrata K. +1 more
openaire +2 more sources
A Japanese case of amoebic meningoencephalitis initially diagnosed by cerebrospinal fluid cytology
Microscopy can detect the presence of amoebic trophozoites in cerebrospinal fluid and tissue. The infection was confirmed in the present case by polymerase chain reaction and immunohistochemistry, but we were unable to achieve a cure. Our case rapidly progressed without any skin lesions.
Ryogo Aoki +8 more
wiley +1 more source
Lethal encounters: The evolving spectrum of amoebic meningoencephalitis
The free-living amoebae are thermophilic organisms that may play an increasing role among diseases of a warming world. They are uncommon, accidental, yet high consequence pathogens, with differing pathologic syndromes.
Sandra G. Gompf, Cristina Garcia
doaj +1 more source

