Results 51 to 60 of about 974 (159)

Disseminated Infection with Balamuthia mandrillaris in a Dog [PDF]

Veterinary Pathology, 2004
Bilateral chronic granulomatous nephritis and meningoencephalitis were diagnosed on necropsy of a 2-year-old male Great Dane dog. The causative agent was identified as Balamuthia mandrillaris, based on morphologic features, immunohistochemical staining, and deoxyribonucleic acid detection using the polymerase chain reaction with newly designed primer ...
O, Foreman, J, Sykes, L, Ball, N, Yang, H, De Cock   +4 more
openaire   +2 more sources

A Novel Balamuthia Lineage Causing Fatal Granulomatous Amoebic Encephalitis in an Immunocompetent Infant

International Journal of Infectious Diseases
Objectives: To characterize a genetically distinct Balamuthia lineage causing fatal granulomatous amoebic encephalitis (GAE) in a 10-month-old infant and highlight diagnostic challenges compounded by SARS-COV-2 infection comorbidity. Methods: Case report
Zhongqiu Teng, Linlin Liu, Tianming Chen, Junrong Liang, Xingfeng Yao, Na Zhao, Fengmao Zhao, Hailang Sun, Lijuan Wang, Quan Wang, Gang Liu, Tian Qin   +11 more
doaj   +1 more source

Rare Infectious Diseases: Detection and Clinical Implications

iLABMED, Volume 3, Issue 2, Page 148-157, June 2025.
Rare infectious diseases are infections that are uncommon, have a low incidence, and are caused by newly emerging pathogens, cross‐species or ectopic infections, or host immunodeficiencies. The detection and diagnosis of rare infections is one of the main reasons for misdiagnosis and missed diagnosis.
Xin Qian, Yuxin Zhang, Yilin Ye, Qiange Lin, Junyou Lin, Xinrong Lu, Li Chen, Guiqin Sun   +7 more
wiley   +1 more source

Clinical, Laboratory Characteristics, and Microorganism Infection Status in Neonates With Meningitis in Vietnam: A Cross‐Sectional Descriptive Study

International Journal of Pediatrics, Volume 2025, Issue 1, 2025.
Objective This study is aimed at describing the clinical and laboratory characteristics and determining the prevalence of microbial pathogens causing neonatal meningitis detected by cerebrospinal fluid (CSF) real‐time polymerase chain reaction (PCR). Materials and Methods A cross‐sectional descriptive study was conducted on 55 neonates diagnosed with ...
Tho Kieu Anh Pham, Binh Thien Nguyen, Phuong Minh Nguyen, Khai Quang Tran, Nikhat Kaura   +4 more
wiley   +1 more source

Emergence of Balamuthia mandrillaris meningoencephalitis in India

Indian Journal of Medical Microbiology, 2015
We report two cases of fatal chronic meningoencephalitis caused by Balamuthia mandrillaris in immunocompetent men. Diagnosis of amoebic meningoencephalitis was made ante-mortem in one case and postmortem in another by histopathological examination and confirmed by demonstration of B. mandrillaris deoxyribonucleic acid (DNA) by polymerase chain reaction
S, Khurana, V, Hallur, M K, Goyal, R, Sehgal, B D, Radotra   +4 more
openaire   +2 more sources

Modelling dynamics between free‐living amoebae and bacteria

Environmental Microbiology, Volume 26, Issue 5, May 2024.
This review scrutinizes mathematical models designed to simulate the interactions between free‐living amoebae and bacteria. Identified gaps encompass (1) the necessity to tackle complexities such as spatial heterogeneity and population diversity; and (2) the essential understanding of the system.
Marwa Ali, Christopher A. Rice, Andrew W. Byrne, Philip E. Paré, Wendy Beauvais   +4 more
wiley   +1 more source

Successful treatment of balamuthia mandrillaris amebic encephalitis diagnosed by MetaCAP in China: A case report and review of 25 survival cases

International Journal of Infectious Diseases
Balamuthia mandrillaris, a free-living amoeba, can cause Balamuthia amebic encephalitis (BAE), a rare and often fatal cerebral infection. The reported mortality rate is >90%, largely attributable to the absence of specific clinical manifestations ...
Yuanwen Zhang, Ji Xia, Zengyun Qiu, Songqin Tian, Jialin Wang, Xiaotong Ren, Mengjia Chen   +6 more
doaj   +1 more source

Glucose metabolism in the pathogenic free‐living amoebae: Tempting targets for treatment development

Chemical Biology &Drug Design, Volume 103, Issue 1, January 2024.
Enzymes involved in glucose metabolism may be promising therapeutic targets for drug development against the pathogenic free‐living amoebae. Details about the enzyme sequence and structural properties make a compelling case for designing small molecule inhibitors that are specific to the amoebae and would not affect the host enzyme.AbstractPathogenic ...
Jillian E. Milanes, Samuel Kwain, Allyson Drawdy, Laura Dodson, Matthew T. Monaghan, Christopher A. Rice, Brian N. Dominy, Daniel C. Whitehead, James C. Morris   +8 more
wiley   +1 more source

Under the Radar: Balamuthia Amebic Encephalitis [PDF]

Clinical Infectious Diseases, 2009
We present data from 9 years (1999-2008) of tests for Balamuthia mandrillaris, an agent of amebic encephalitis that were conducted as part of the California Encephalitis Project.Specimens obtained from patients with encephalitis were sent to the California Encephalitis Project for diagnostic testing; a subset of these specimens were tested for ...
Frederick L, Schuster, Shigeo, Yagi, Shilpa, Gavali, David, Michelson, Ravi, Raghavan, Ingrid, Blomquist, Christine, Glastonbury, Andrew W, Bollen, David, Scharnhorst, Sharon L, Reed, Steve, Kuriyama, Govinda S, Visvesvara, Carol A, Glaser   +12 more
openaire   +2 more sources

Prognostic Factors and Treatment Outcomes in Pediatric Balamuthia Amoebic Encephalitis: A Case Report and Literature Review

Infectious Microbes & Diseases
Balamuthia amoebic encephalitis (BAE) is a rare and often fatal central nervous system infection caused by the free-living protozoon Balamuthia mandrillaris. Identifying the prognostic factors that affect the survival of pediatric patients is crucial for
Juan-Juan Liu, Yong-Ping Xie, Lei Wang, Lv-Chang Zhu, Yi Shi, Wu-Jie Shi, Ao-Le Li, Wang Hua, Zhi-Peng Shen, Da-Qing Ma, Li-Su Huang   +10 more
doaj   +1 more source