Results 51 to 60 of about 1,360 (188)

Balamuthia mandrillaris

Tropical Parasitology, 2021
Balamuthia mandrillaris is an opportunistic, free-living ameba that is pathogenic to humans. It has a worldwide distribution but is mainly detected in warmer regions. Balamuthia infections are rare but have been reported in both immunocompetent and immunocompromised individuals of all ages. B.
Bhosale, Namrata K., Parija, Subhash Chandra   +1 more
openaire   +2 more sources

Discovery of repurposing drug candidates for the treatment of diseases caused by pathogenic free-living amoebae.

PLoS Neglected Tropical Diseases, 2020
Diseases caused by pathogenic free-living amoebae include primary amoebic meningoencephalitis (Naegleria fowleri), granulomatous amoebic encephalitis (Acanthamoeba spp.), Acanthamoeba keratitis, and Balamuthia amoebic encephalitis (Balamuthia ...
Christopher A Rice, Beatrice L Colon, Emily Chen, Mitchell V Hull, Dennis E Kyle   +4 more
doaj   +1 more source

Post-mortem culture of Balamuthia mandrillaris from the brain and cerebrospinal fluid of a case of granulomatous amoebic meningoencephalitis, using human brain microvascular endothelial cells

, 2004
The first isolation in the UK of Balamuthia mandrillaris amoebae from a fatal case of granulomatous amoebic meningoencephalitis is reported. Using primary cultures of human brain microvascular endothelial cells (HBMECs), amoebae were isolated from the ...
Rogers, Claire, Alsam, S., Nolder, Debbie, Rogers, C., Sissons, J., Nolder, D., Jayasekera, S., Alsam, Selwa, Tucker, J., Warhurst, D., White, J.M.L., Jayasekera, Samantha, Higgins, E.M., Sissons, James, Higgins, EM, Khan, Naveed Ahmed, Warhurst, David, White, Jonathan ML, Tucker, Julie   +18 more
core   +1 more source

Phenotypic assays for Balamuthia mandrillaris.

, 2020
(A)Assays performed: Schematic representing the workflow for each of the assays performed for Balamuthia. Red arrows represent addition of drug and outline arrows represent drug removal.
Gretchen Ehrenkaufer (8605254), Joseph DeRisi (30467), Jolyn Gisselberg (8605266), Pengyang Li (4449448), Conor R. Caffrey (113916), Anjan Debnath (352163), Upinder Singh (29923), Christopher D. Huston (8605275), Erin E. Stebbins (8605257), Ellen Yeh (207853), Steven C. Wang (8605269), Bo Wang (86769), Matthew S. Moser (8605263), Monica M. Kangussu-Marcolino (8605260), Ludovica Monti (1484272), Corin V. White (5644118), Ana Hervella Company (8605272)   +16 more
core   +1 more source

Molecular analysis unmasking a Balamuthia mandrillaris: Skin lesion and granulomatous amebic encephalitis by Acanthamoeba sp close to genotype T4 with fatal outcome

Clinical Infection in Practice
Background: Acanthamoeba sp, Balamuthia mandrillaris, are a free-living soil amoeba, has emerged as a causative agent of chronic GAE. Methods: The nasal biopsy was sent to our Laboratory of Pathogenic Protozoa and Endosymbionts (LPEP).
Alfonso Martín Cabello-Vílchez, M. Isabel Ruiz-Ruiz   +1 more
doaj   +1 more source

Identification of plicamycin, TG02, panobinostat, lestaurtinib, and GDC-0084 as promising compounds for the treatment of central nervous system infections caused by the free-living amebae Naegleria, Acanthamoeba and Balamuthia

International Journal for Parasitology: Drugs and Drug Resistance, 2019
The free-living amebae Naegleria, Acanthamoeba, and Balamuthia cause rare but life-threatening infections. All three parasites can cause meningoencephalitis.
Monica M. Kangussu-Marcolino, Gretchen M. Ehrenkaufer, Emily Chen, Anjan Debnath, Upinder Singh   +4 more
doaj   +1 more source

A Novel Protistan Trait Database Reveals Functional Redundancy and Complementarity in Terrestrial Protists (Amoebozoa and Rhizaria)

Molecular Ecology Resources, Volume 26, Issue 1, January 2026.
ABSTRACT The inclusion of functional traits of protists in environmental sequencing surveys, in addition to the traditional taxonomic framework, is essential for a better understanding of their roles and impacts on ecosystem processes. We provide a database of functional traits for a widespread and important clade of protists—the Amoebozoa—based on ...
Jule Freudenthal, Martin Schlegel, Michael Bonkowski, Kenneth Dumack   +3 more
wiley   +1 more source

ISEV2023 Abstract Book

, 2023
Journal of Extracellular Vesicles, Volume 12, Issue S1, May 2023.
wiley   +1 more source

Emergence of Balamuthia mandrillaris meningoencephalitis in India

Indian Journal of Medical Microbiology, 2015
We report two cases of fatal chronic meningoencephalitis caused by Balamuthia mandrillaris in immunocompetent men. Diagnosis of amoebic meningoencephalitis was made ante-mortem in one case and postmortem in another by histopathological examination and confirmed by demonstration of B. mandrillaris deoxyribonucleic acid (DNA) by polymerase chain reaction
S, Khurana, V, Hallur, M K, Goyal, R, Sehgal, B D, Radotra   +4 more
openaire   +2 more sources

Under the Radar: Balamuthia Amebic Encephalitis [PDF]

Clinical Infectious Diseases, 2009
We present data from 9 years (1999-2008) of tests for Balamuthia mandrillaris, an agent of amebic encephalitis that were conducted as part of the California Encephalitis Project.Specimens obtained from patients with encephalitis were sent to the California Encephalitis Project for diagnostic testing; a subset of these specimens were tested for ...
Frederick L, Schuster, Shigeo, Yagi, Shilpa, Gavali, David, Michelson, Ravi, Raghavan, Ingrid, Blomquist, Christine, Glastonbury, Andrew W, Bollen, David, Scharnhorst, Sharon L, Reed, Steve, Kuriyama, Govinda S, Visvesvara, Carol A, Glaser   +12 more
openaire   +2 more sources