Results 71 to 80 of about 1,360 (188)
First Draft Genome Sequence of Balamuthia mandrillaris, the Causative Agent of Amoebic Encephalitis [PDF]
, 2015 The free-living amoeba Balamuthia mandrillaris is a rare but highly lethal agent of amoebic encephalitis in humans and many other mammalian species. Here, we announce the first draft genome sequence of the original 1990 isolate cultured from the brain of
Detering, H. +6 more
core +1 more source
, 2011 Mostra uma imagem de Balamuthia, uma ameba que foi primeiramente isolada como agente infeccioso de cérebros de primatas (não humanos).
Nerad, Tom +3 more
core +1 more source
Glucose metabolism in the pathogenic free‐living amoebae: Tempting targets for treatment development
Chemical Biology &Drug Design, Volume 103, Issue 1, January 2024.Enzymes involved in glucose metabolism may be promising therapeutic targets for drug development against the pathogenic free‐living amoebae. Details about the enzyme sequence and structural properties make a compelling case for designing small molecule inhibitors that are specific to the amoebae and would not affect the host enzyme.AbstractPathogenic ...
Jillian E. Milanes +8 more
wiley +1 more source
Sequences and draft annotations of computationally predicted proteins from Balamuthia mandrillaris
, 2021 This file contains the sequences and draft annotations of computationally predicted proteins from Balamuthia mandrillaris. The sequences are reconstructed from RNA sequencing of logarithmic phase trophozoites, the infective form of the amoeba. Reads were
Phan, Isabelle Q. +12 more
core +1 more source
Transmission ofBalamuthia mandrillarisby Organ Transplantation [PDF]
Clinical Infectious Diseases, 2016 During 2009 and 2010, 2 clusters of organ transplant-transmitted Balamuthia mandrillaris, a free-living ameba, were detected by recognition of severe unexpected illness in multiple recipients from the same donor.We investigated all recipients and the 2 donors through interview, medical record review, and testing of available specimens retrospectively ...
Eileen C, Farnon +43 more
openaire +2 more sources
Balamuthia mandrillarisexhibits metalloprotease activities [PDF]
FEMS Immunology & Medical Microbiology, 2006 Balamuthia mandrillaris is a recently identified protozoan pathogen that can cause fatal granulomatous encephalitis. However, the pathogenesis and pathophysiology of B. mandrillaris encephalitis remain unclear. Because proteases may play a role in the central nervous system (CNS) pathology, we used spectrophotometric, cytopathic and zymographic assays ...
Abdul, Matin +3 more
openaire +2 more sources
Isolation of Acanthamoeba sp. y Balamuthia mandrillaris from commercial soil from a supermarket in Lima [PDF]
, 2021 Antecedentes: Los altos índices de letalidad en casos de infecciones humanas causadas por amebas de vida libre y su papel como reservorio de microorganismos patógenos ha impulsado su identificación en ambientes como la tierra.
Fernández Costilla, Fernando de Jesús +1 more
core
Parasites & Vectors, 2022 Background Environmental protozoa need an adaptation mechanism to survive drastic changes in niches in the human body. In the brain parenchyma, Balamuthia mandrillaris trophozoites, which are causative agents of fatal brain damage, must acquire nutrients
Worakamol Pengsart +4 more
doaj +1 more source
, 2013 Balamuthia mandrillaris causes granulomatous amoebic encephalitis, which is frequently fatal. There are few reports of survival in children. A 4-year-old child developed severe meningoencephalitis with multiple intracranial ring-enhancing lesions ...
Campbell, Robert +7 more
core +1 more source
The prevalence of free-living amoebae in a South African hospital water distribution system
South African Journal of Science, 2015 The purpose of this study was to investigate the occurrence of free-living amoebae in the water system of a teaching hospital in Johannesburg (South Africa).
Petros Muchesa +2 more
doaj +1 more source