Results 81 to 90 of about 1,383 (171)

Balamuthia amoebic encephalitis directly causing intracranial infection: A case report

Radiology Case Reports
Balamuthia amoebic encephalitis (BAE) is a rare and often fatal central nervous system (CNS) infection caused by Balamuthia mandrillaris, a free-living amoeba typically found in soil and water. This organism can invade the brain directly, bypassing other
Yuhan Liang, Yanhong Liu, Zelong Chen, Jiayi Sun, Xuemeng Zhang, Yulin Wang   +5 more
doaj   +1 more source

Identification of Antigenic Targets for Immunodetection of Balamuthia mandrillaris Infection [PDF]

Clinical and Vaccine Immunology, 2011
ABSTRACTThe free-living amoebaBalamuthia mandrillariscauses granulomatous amoebic encephalitis (GAE) in humans. Rapid identification of balamuthiasis is critical for effective therapeutic intervention and case management. In the present study we identified target antigens for the development of a serological assay forB. mandrillarisinfection.
Zuzana, Kucerova, Rama, Sriram, Patricia P, Wilkins, Govinda S, Visvesvara   +3 more
openaire   +2 more sources

Isolation of balamuthia mandrillaris-specific antibody fragments from a bacteriophage antibody display library

, 2016
Balamuthia mandrillaris is a protist pathogen that can cause encephalitis with a mortality rate of more than 95%. Early diagnosis followed by aggressive treatment is a pre-requisite for successful prognosis.
Siddiqui, Ruqaiyyah, Lalani, Salima, Khan, Naveed Ahmed, Kulsoom, Huma   +3 more
core   +1 more source

Granulomatous amebic encephalitis in a patient treated with chemotherapy: a case report and literature review [PDF]

Journal of Neurocritical Care
Background Granulomatous amebic encephalitis (GAE) is caused by Acanthamoeba species or Balamuthia mandrillaris, which are microscopic, free-living amoebas found worldwide. People with compromised immune systems are at an increased risk of fatal cerebral
Marcos R. Flores, Miranda G. Montion, Aneesha N. Usman, Munachiso A. Ngene, Samir Ruxmohan   +4 more
doaj   +1 more source

Image_1_Phenotypic assay for cytotoxicity assessment of Balamuthia mandrillaris against human neurospheroids.TIF

, 2023
IntroductionThe phenotypic screening of drugs against Balamuthia mandrillaris, a neuropathogenic amoeba, involves two simultaneous phases: an initial step to test amoebicidal activity followed by an assay for cytotoxicity to host cells.
Narisara Whangviboonkij (12967853), Zhenzhong Chen (9385775), Seokgyu Han (11929869), Kasem Kulkeaw (798157), Sungsu Park (122089), Worakamol Pengsart (12967850)   +5 more
core   +1 more source

Influence of the Age of Free-Living Amoeba Cysts on Their Vertical Distribution in a Water Column

Microorganisms
Free-living amoebae (FLA) are widely distributed protozoa in both natural and artificial environments such as drinking water. In addition to the ability of all FLA to transport various pathogenic microorganisms, certain species, such as Acanthamoeba spp.
Zineb Fechtali-Moute, Sébastien Pomel
doaj   +1 more source

Balamuthia mandrillaris therapeutic mud bath in Jamaica

Epidemiology and Infection, 2014
SUMMARYBalamuthia mandrillaris is an emerging cause of encephalitis in humans. The transmission dynamics are poorly understood due to the high fatality rate and the sporadic nature of cases. Seventy-two soil samples were collected from beaches and the banks of lagoons, rivers, ponds, mineral springs and streams from across Jamaica and assayed for the ...
C D, Todd, M, Reyes-Batlle, J E, Piñero, E, Martínez-Carretero, B, Valladares, J F, Lindo, J, Lorenzo-Morales   +6 more
openaire   +2 more sources

Balamuthia Mandrillaris Encephalitis: Slow but Lethal March Towards the Brain

Balamuthia mandrillaris causes granulomatous amebic encephalitis. It is puzzling that unlike many blood-borne pathogens that can invade the central nervous system within hours, B.
Siddiqui, Ruqaiyyah; id_orcid, Khan, Naveed Ahmed, Maciver, Sutherland Kester, Siddiqui, Ruqaiyyah   +3 more
core   +1 more source

Image_2_Phenotypic assay for cytotoxicity assessment of Balamuthia mandrillaris against human neurospheroids.TIF

, 2023
IntroductionThe phenotypic screening of drugs against Balamuthia mandrillaris, a neuropathogenic amoeba, involves two simultaneous phases: an initial step to test amoebicidal activity followed by an assay for cytotoxicity to host cells.
Narisara Whangviboonkij (12967853), Narisara Whangviboonkij, Zhenzhong Chen (9385775), Seokgyu Han (11929869), Kasem Kulkeaw (798157), Kasem Kulkeaw, Zhenzhong Chen, Seokgyu Han, Sungsu Park (122089), Worakamol Pengsart, Sungsu Park, Worakamol Pengsart (12967850)   +11 more
core   +1 more source

Discovery of Anti-Amoebic Inhibitors from Screening the MMV Pandemic Response Box on Balamuthia mandrillaris, Naegleria fowleri, and Acanthamoeba castellanii

Pathogens, 2020
Pathogenic free-living amoebae, Balamuthia mandrillaris, Naegleria fowleri, and several Acanthamoeba species are the etiological agents of severe brain diseases, with case mortality rates > 90%.
Christopher A. Rice, Emma V. Troth, A. Cassiopeia Russell, Dennis E. Kyle   +3 more
doaj   +1 more source