Results 61 to 70 of about 891 (153)

Xenic Cultivation and Genotyping of Pathogenic Free‐Living Amoeba from Public Water Supply Sources in Uganda

New Journal of Science, Volume 2016, Issue 1, 2016., 2016
Studies on waterborne parasites from natural environment and domestic water sources in Uganda are very scarce and unpublished. Water dwelling free‐living amoebae (FLA) of the genus Acanthamoeba, Hartmannella, and Naegleria are often responsible for causing morbidities and mortalities in individuals with recent contact with contaminated water, but their
Celsus Sente, Joseph Erume, Irene Naigaga, Benigna Gabriela Namara, Julius Mulindwa, Sylvester Ochwo, Phillip Kimuda Magambo, Charles Drago Kato, Andrew Tamale, Michael Ocaido, Xinhua Shu   +10 more
wiley   +1 more source

Discovery of repurposing drug candidates for the treatment of diseases caused by pathogenic free-living amoebae.

PLoS Neglected Tropical Diseases, 2020
Diseases caused by pathogenic free-living amoebae include primary amoebic meningoencephalitis (Naegleria fowleri), granulomatous amoebic encephalitis (Acanthamoeba spp.), Acanthamoeba keratitis, and Balamuthia amoebic encephalitis (Balamuthia ...
Christopher A Rice, Beatrice L Colon, Emily Chen, Mitchell V Hull, Dennis E Kyle   +4 more
doaj   +1 more source

Bulk and single-cell transcriptome profiling reveals the dynamic immune response in granulomatous amebic encephalitis caused by Balamuthia mandrillaris: a cohort study

Frontiers in Immunology
Introduction Balamuthia mandrillaris infection in humans is rare and usually fatal. It is well established that B. mandrillaris can cause granulomatous amebic encephalitis (GAE). However, little is known about the factors that determine B.
Jingjia Zhang, Xinmiao Jia, Bin Yang, Ying Ge, Wei Jiang, Y. Cong, Huanwen Wu, Huifang Liu, Jingjing Tian, YingChun Xu, Qiwen Yang   +10 more
semanticscholar   +1 more source

Diagnosing Balamuthia mandrillaris amebic meningoencephalitis in a 64-year-old woman from the Southwest of China

Parasites, hosts and diseases, 2023
Balamuthia mandrillaris amebic encephalitis (BAE) can cause a fatal condition if diagnosis is delayed or effective treatment is lacking. Patients with BAE have been previously reported in 12 provinces of China, with skin lesions being the primary symptom
Suhua Yao, Xiaoting Chen, Lian Qian, Shizheng Sun, Chunjing Zhao, Zongkai Bai, Zhaofang Chen, Youcong Wu   +7 more
semanticscholar   +1 more source

Stress Management in Cyst‐Forming Free‐Living Protists: Programmed Cell Death and/or Encystment

BioMed Research International, Volume 2015, Issue 1, 2015., 2015
In the face of harsh conditions and given a choice, a cell may (i) undergo programmed cell death, (ii) transform into a cancer cell, or (iii) enclose itself into a cyst form. In metazoans, the available evidence suggests that cellular machinery exists only to execute or avoid programmed cell death, while the ability to form a cyst was either lost or ...
Naveed Ahmed Khan, Junaid Iqbal, Ruqaiyyah Siddiqui, Philippe Holzmuller   +3 more
wiley   +1 more source

Application of ventriculoscopy in granulomatous amoebic encephalitis: a case report in China and literature review

Frontiers in Medicine
Balamuthia mandrillaris is a kind of brain-eating amoeba leading to granulomatous amoebic encephalitis (GAE) with a high mortality rate and limited effective treatment options. Its underlying pathological mechanisms are still poorly understood.
Zequan Zheng, Zequan Zheng, Fajun Chen, Lulu Qin, Aili Lu, Haoyou Xu, Min Zhao, Yuanqi Zhao   +7 more
doaj   +1 more source

Rare Infectious Diseases: Detection and Clinical Implications

iLABMED, Volume 3, Issue 2, Page 148-157, June 2025.
Rare infectious diseases are infections that are uncommon, have a low incidence, and are caused by newly emerging pathogens, cross‐species or ectopic infections, or host immunodeficiencies. The detection and diagnosis of rare infections is one of the main reasons for misdiagnosis and missed diagnosis.
Xin Qian, Yuxin Zhang, Yilin Ye, Qiange Lin, Junyou Lin, Xinrong Lu, Li Chen, Guiqin Sun   +7 more
wiley   +1 more source

Pulmonary infection due to Balamuthia mandrillaris in the southwestern United States: not all miliary disease is tuberculosis and coccidioidomycosis

ASM case reports
Background Balamuthia mandrillaris is a rare cause of skin and/or central nervous system (CNS) infection with a high mortality rate. Dissemination to other organs, including the lungs, is rare.
N. Price, H. Pariury, J. Papic, M. Anthony, W. Lainhart, K. Shehab   +5 more
semanticscholar   +1 more source

Clinical, Laboratory Characteristics, and Microorganism Infection Status in Neonates With Meningitis in Vietnam: A Cross‐Sectional Descriptive Study

International Journal of Pediatrics, Volume 2025, Issue 1, 2025.
Objective This study is aimed at describing the clinical and laboratory characteristics and determining the prevalence of microbial pathogens causing neonatal meningitis detected by cerebrospinal fluid (CSF) real‐time polymerase chain reaction (PCR). Materials and Methods A cross‐sectional descriptive study was conducted on 55 neonates diagnosed with ...
Tho Kieu Anh Pham, Binh Thien Nguyen, Phuong Minh Nguyen, Khai Quang Tran, Nikhat Kaura   +4 more
wiley   +1 more source

Novel Azoles as Antiparasitic Remedies against Brain-Eating Amoebae

Antibiotics, 2020
Balamuthia mandrillaris and Naegleria fowleri are opportunistic protozoan pathogens capable of producing infection of the central nervous system with more than 95% mortality rate.
Ayaz Anwar, Mohammad Ridwane Mungroo, Simal Khan, Itrat Fatima, Rafaila Rafique, Kanwal, Khalid Mohammed Khan, Ruqaiyyah Siddiqui, Naveed Ahmed Khan   +8 more
doaj   +1 more source