Results 41 to 50 of about 1,383 (171)

A Case of Balamuthia mandrillaris Meningoencephalitis [PDF]

Archives of Neurology, 2000
Balamuthia mandrillaris is a newly described pathogen that causes granulomatous amebic encephalitis, an extremely rare clinical entity that usually occurs in immunosuppressed individuals. We report a case of pathologically proven Balamuthia encephalitis with unusual laboratory and radiologic findings.
J D, Katz, A H, Ropper, L, Adelman, M, Worthington, P, Wade   +4 more
openaire   +2 more sources

Guidelines for the purification and characterization of extracellular vesicles of parasites

Journal of Extracellular Biology, Volume 2, Issue 10, October 2023., 2023
Abstract Parasites are responsible for the most neglected tropical diseases, affecting over a billion people worldwide (WHO, 2015) and accounting for billions of cases a year and responsible for several millions of deaths. Research on extracellular vesicles (EVs) has increased in recent years and demonstrated that EVs shed by pathogenic parasites ...
Carmen Fernandez‐Becerra, Patrícia Xander, Daniel Alfandari, George Dong, Iris Aparici‐Herraiz, Irit Rosenhek‐Goldian, Mehrdad Shokouhy, Melisa Gualdron‐Lopez, Nicholy Lozano, Nuria Cortes‐Serra, Paula Abou Karam, Paula Meneghetti, Rafael Pedro Madeira, Ziv Porat, Rodrigo Pedro Soares, Adriana Oliveira Costa, Sima Rafati, Anabela‐Cordeiro da Silva, Nuno Santarém, Christopher Fernandez‐Prada, Marcel I. Ramirez, Dolores Bernal, Antonio Marcilla, Vera Lucia Pereira‐Chioccola, Lysangela Ronalte Alves, Hernando Del Portillo, Neta Regev‐Rudzki, Igor Correia de Almeida, Sergio Schenkman, Martin Olivier, Ana Claudia Torrecilhas   +30 more
wiley   +1 more source

Amoebic Encephalitis Caused by Balamuthia mandrillaris [PDF]

Journal of Pathology and Translational Medicine, 2019
We present the case of a 71-year-old man who was diagnosed with amoebic encephalitis caused by Balamuthia mandrillaris. He had rheumatic arthritis for 30 years and had undergone continuous treatment with immunosuppressants.
Su Jung Kum, Hye Won Lee, Hye Ra Jung, Misun Choe, Sang Pyo Kim   +4 more
doaj   +1 more source

Environmentally derived Balamuthia mandrillaris contains endosymbiotic bacteria. [PDF]

Parasitol Res
Balamuthia mandrillaris is an environmentally derived, free-living amoeba that causes fatal meningoencephalitis. We previously isolated B. mandrillaris from soil in the Aomori Prefecture and attempted to culture the cell-free amoeba using liquid medium; however, this was difficult to achieve because of contamination of the medium with endogenous ...
Yamanouchi K, Nagai T, Tsujiguchi T, Chiba M, Fujioka M, Ahsan CR, Matsumiya T.   +6 more
europepmc   +3 more sources

Free‐Living Amoebas in Extreme Environments: The True Survival in our Planet

BioMed Research International, Volume 2022, Issue 1, 2022., 2022
Free‐living amoebas (FLAs) are microorganisms, unicellular protozoa widely distributed in nature and present in different environments, such as water or soil; they are maintained in ecosystems and play a fundamental role in the biological control of bacteria, other protozoa, and mushrooms.
Camila Salazar-Ardiles, Leyla Asserella-Rebollo, David C. Andrade, Syed Hassan   +3 more
wiley   +1 more source

Drugs used for the treatment of cerebral and disseminated infections caused by free‐living amoebae

Clinical and Translational Science, Volume 14, Issue 3, Page 791-805, May 2021., 2021
Abstract Free‐living amoebae (FLAs) are protozoa developing autonomously in diverse natural or artificial environments. The FLAs Acanthamoeba spp., Balamuthia mandrillaris, and Naegleria fowleri represent a risk for human health as they can become pathogenic and cause severe cerebral infections, named granulomatous amoebic encephalitis (GAE ...
Alexandre Taravaud, Zineb Fechtali‐Moute, Philippe M. Loiseau, Sébastien Pomel   +3 more
wiley   +1 more source

Post-mortem culture of Balamuthia mandrillaris from the brain and cerebrospinal fluid of a case of granulomatous amoebic meningoencephalitis, using human brain microvascular endothelial cells [PDF]

, 2004
The first isolation in the UK of Balamuthia mandrillaris amoebae from a fatal case of granulomatous amoebic meningoencephalitis is reported. Using primary cultures of human brain microvascular endothelial cells (HBMECs), amoebae were isolated from the ...
Rogers, Claire, Alsam, S., Nolder, Debbie, Rogers, C., Sissons, J., Nolder, D., Jayasekera, S., Alsam, Selwa, Tucker, J., Warhurst, D., White, J.M.L., Jayasekera, Samantha, Higgins, E.M., Sissons, James, Higgins, EM, Khan, Naveed Ahmed, Warhurst, David, White, Jonathan ML, Tucker, Julie   +18 more
core   +1 more source

Diagnosis of Balamuthia mandrillaris Encephalitis by Thymine-Adenine Cloning Using Universal Eukaryotic Primers. [PDF]

Ann Lab Med, 2022
Background: Identifying the causal pathogen of encephalitis remains a clinical challenge. A 50-year-old man without a history of neurological disease was referred to our department for the evaluation of an intracranial lesion observed on brain magnetic ...
Kim JY, Yi MH, Kim M, Yeom JS, Yoo HD, Kim SM, Yong TS.   +6 more
europepmc   +2 more sources

A 76‐year‐old male with multiple enhancing brain lesions

, 2022
Brain Pathology, Volume 32, Issue 3, May 2022.
Kathryn L. Eschbacher, Derek R. Johnson, Sylvia L. Orozco‐Do, Tabinda Jawaid, Audrey N. Schuetz, Aivi T. Nguyen   +5 more
wiley   +1 more source

A Japanese case of amoebic meningoencephalitis initially diagnosed by cerebrospinal fluid cytology

Clinical Case Reports, Volume 8, Issue 9, Page 1728-1734, September 2020., 2020
Microscopy can detect the presence of amoebic trophozoites in cerebrospinal fluid and tissue. The infection was confirmed in the present case by polymerase chain reaction and immunohistochemistry, but we were unable to achieve a cure. Our case rapidly progressed without any skin lesions.
Ryogo Aoki, Toshimasa Sakakima, Asuka Ohashi, Riyoko Niwa, Masashi Matsuyama, Fumimasa Etori, Naoki Watanabe, Kenji Yagita, Takuji Tanaka   +8 more
wiley   +1 more source